基于系统药理学分析三七总皂苷干预脑血管疾病的作用机制(5)
[6] QI B， ZHANG L， ZHANG Z， et al. Effects of ginsenosides-Rb1 on exercise-induced oxidative stress in forced swimming mice[J]. Pharmacogn Mag， 2014， 10(40)： 458-463.
[7] GONZ？譧LEZ-BURGOS E， FERN？譧NDEZ-MORIANO C， LOZANO R， et al. Ginsenosides Rd and Re co-treatments improve rotenone-induced oxidative stress and mitochondrial impairment in SH-SY5Y neuroblastoma cells[J]. Food ChemToxicol. 2017， 109(1)： 38-47.
[8] PARK S Y， PARK J H， KIM H S， et al. Systems-level mechanisms of action of Panax ginseng： a network pharmacological approach[J]. J Ginseng Res， 2018， 42(1)：98-106.
, http://www.100md.com
[9] CHOUDHARY N， SINGH V. A census of P. longum's phytochemicals and their network pharmacological evaluation for identifying novel drug-like molecules against various diseases， with a special focus on neurological disorders[J]. PLoS One. 2018， 13(1)：e0191006.
[10] LIU Y， LIANG Y， WISHART D. PolySearch2： a significantly improved text-mining system for discovering associations between human diseases， genes， drugs， metabolites， toxins and more[J]. Nucleic Acids Res， 2015， 43 (W1)： W535-W542.
, 百拇医药
[11] LUO H， CHEN J， SHI L， et al. DRAR-CPI： a server for identifying drug repositioning potential and adverse drug reactions via the chemical-protein interactome[J]. Nucleic Acids Res， 2011， 39 (WebServer issue)：W492-W498.
[12] KIM J， SO S， LEE H J， et al. DigSee： Disease gene search engine with evidence sentences (version cancer)[J]. Nucleic Acids Res， 2013， 41(Web Server issue)： W510-W517.
[13] SHANNON P， MARKIEL A， OZIER O， et al. Cytoscape： a software environment for integrated models of biomolecular interaction networks [J].Genome Res， 2003， 13 (11)： 2498-2504.
, 百拇医药
[14] MARTIN A， OCHAGAVIA M E， RABASA L C， et al. BisoGenet： a new tool for gene network building， visualization and analysis[J]. BMC Bioinformatics， 2010，17(2)， 11： 91.
[15] TANG Y， LI M， WANG J， et al. CytoNCA： a cytoscape plugin for centrality analysis and evaluation of protein interaction networks [J]. Biosystems， 2015， 127： 67-72.
[16] BINDEA G， MLECNIK B， HACKI H， et al. ClueGO： a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks[J]. Bioinformatics. 2009， 25(8)： 1091-1093.
, 百拇医药
[17] WANG S， WANG H， LU Y. Tianfoshen oral liquid： a CFDA approved clinical traditional Chinese medicine， normalizes major cellular pathways disordered during colorectal carcinogenesis[J]. Oncotarget， 2017， 8(9)：14549-14569.
[18] RODRIGO R， FERN？譧NDEZ-GAJARDO R， GUTI？魪RREZ R， et al. Oxidative stress and pathophysiology of ischemic stroke： novel therapeutic opportunities[J]. CNS NeurolDisord Drug Targets， 2013， 12(5)：698-714., http://www.100md.com(聂娟 唐标)
[7] GONZ？譧LEZ-BURGOS E， FERN？譧NDEZ-MORIANO C， LOZANO R， et al. Ginsenosides Rd and Re co-treatments improve rotenone-induced oxidative stress and mitochondrial impairment in SH-SY5Y neuroblastoma cells[J]. Food ChemToxicol. 2017， 109(1)： 38-47.
[8] PARK S Y， PARK J H， KIM H S， et al. Systems-level mechanisms of action of Panax ginseng： a network pharmacological approach[J]. J Ginseng Res， 2018， 42(1)：98-106.
, http://www.100md.com
[9] CHOUDHARY N， SINGH V. A census of P. longum's phytochemicals and their network pharmacological evaluation for identifying novel drug-like molecules against various diseases， with a special focus on neurological disorders[J]. PLoS One. 2018， 13(1)：e0191006.
[10] LIU Y， LIANG Y， WISHART D. PolySearch2： a significantly improved text-mining system for discovering associations between human diseases， genes， drugs， metabolites， toxins and more[J]. Nucleic Acids Res， 2015， 43 (W1)： W535-W542.
, 百拇医药
[11] LUO H， CHEN J， SHI L， et al. DRAR-CPI： a server for identifying drug repositioning potential and adverse drug reactions via the chemical-protein interactome[J]. Nucleic Acids Res， 2011， 39 (WebServer issue)：W492-W498.
[12] KIM J， SO S， LEE H J， et al. DigSee： Disease gene search engine with evidence sentences (version cancer)[J]. Nucleic Acids Res， 2013， 41(Web Server issue)： W510-W517.
[13] SHANNON P， MARKIEL A， OZIER O， et al. Cytoscape： a software environment for integrated models of biomolecular interaction networks [J].Genome Res， 2003， 13 (11)： 2498-2504.
, 百拇医药
[14] MARTIN A， OCHAGAVIA M E， RABASA L C， et al. BisoGenet： a new tool for gene network building， visualization and analysis[J]. BMC Bioinformatics， 2010，17(2)， 11： 91.
[15] TANG Y， LI M， WANG J， et al. CytoNCA： a cytoscape plugin for centrality analysis and evaluation of protein interaction networks [J]. Biosystems， 2015， 127： 67-72.
[16] BINDEA G， MLECNIK B， HACKI H， et al. ClueGO： a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks[J]. Bioinformatics. 2009， 25(8)： 1091-1093.
, 百拇医药
[17] WANG S， WANG H， LU Y. Tianfoshen oral liquid： a CFDA approved clinical traditional Chinese medicine， normalizes major cellular pathways disordered during colorectal carcinogenesis[J]. Oncotarget， 2017， 8(9)：14549-14569.
[18] RODRIGO R， FERN？譧NDEZ-GAJARDO R， GUTI？魪RREZ R， et al. Oxidative stress and pathophysiology of ischemic stroke： novel therapeutic opportunities[J]. CNS NeurolDisord Drug Targets， 2013， 12(5)：698-714., http://www.100md.com(聂娟 唐标)