黄政德教授治疗慢性胃炎的用药规律聚(1)
〔摘要〕 目的 采用聚類分析统计方法，分析第五批全国老中医药专家学术经验继承工作指导老师黄政德教授治疗慢性胃炎用药规律。方法 收集黄政德教授门诊治疗慢性胃炎显效病例，采用Excel统计软件对患者中药处方进行频数统计，并对高频中药功效进行拆分合并，采用SPSS 21.0分析软件，对高频中药基于功效进行聚类分析。结果 共收集了127例慢性胃炎患者，总计190次门诊病历，共运用中药95味，其中高频中药46味，使用频次排名前十的中药为甘草、白芍、木香、茯苓、法半夏、陈皮、柴胡、川芎、延胡索、白术。获得4个聚类方，C1方能理气活血、健脾祛湿、消痞止痛，由柴胡疏肝散与六君子汤加减化裁而来;C2方能通调三焦、健脾祛湿消痞、疏肝解郁，由三仁汤化裁而来;C3方能养阴清胃、健脾活血止痛、疏肝解郁，由一贯煎化裁而来;C4方能清肝泻火、降逆止呕、寒热平调，由左金丸化裁而来。结论 黄政德教授治疗慢性胃炎强调辨病辨证、重调气血、兼顾情志，治疗慢性胃炎善于理气活血、健脾祛湿、疏肝和胃、寒热平调。
〔关键词〕 慢性胃炎;聚类分析;理气活血;健脾祛湿;疏肝和胃;黄政德
〔中图分类号〕R256.3 〔文献标志码〕A 〔文章编号〕doi：10.3969/j.issn.1674-070X.2019.03.015
A Cluster Analysis of Professor Huang Zhengde's Medication Rule in the
Treatment of Chronic Gastritis
YANG Lishuang， HUANG Zhengde*， WU Ruoxia， REN Ting， ZHOU Leqing
(Hunan University of Chinese Medicine， Changsha， Hunan 410208， China)
〔Abstract〕 Objective To investigate the medication rule of Professor Huang Zhengde， an advisor for national traditional Chinese medicine (TCM) experience inheritance work (5th session)， in the treatment of chronic gastritis by a cluster analysis. Methods The clinical data of patients with chronic gastritis who were treated by Professor Huang Zhengde in the outpatient service and achieved marked response were collected， and EXCEL was used to analyze the frequency of TCM prescriptions. The function of highly frequently used TCM herbs was analyzed， and SPSS 21.0 was used to perform the cluster analysis. Results A total of 127 patients with chronic gastritis were enrolled， with 190 outpatient medical records in total. A total of 95 TCM herbs were used， among which 46 were highly frequently used herbs. The 10 most frequently used herbs were Radix Glycyrrhizae， Radix Paeoniae Alba， Saussurea costus， Poria cocos， Rhizoma Pinelliae Praeparatum， tangerine peel， Bupleurum chinense， Rhizoma Ligustici Chuanxiong， Rhizoma Corydalis， and Atractylodes macrocephala. Four clustering prescriptions were obtained. C1 prescription could regulate Qi and activate blood circulation， strengthen the spleen and eliminate dampness， and eliminate abdominal mass and alleviate pain and was formed by modifying Chaihu Shugan Powder and Liujunzi Decoction; C2 prescription could regulate triple energizers， strengthen the spleen， eliminate dampness and abdominal mass， and soothe the liver and resolve stagnation and was formed by modifying Sanren Decoction; C3 prescription could nourish Yin and clear the stomach， strengthen the spleen， activate blood circulation， and alleviate pain， and soothe the liver and resolve stagnation and was formed by modifying Yiguan Decoction; C4 prescription could clear liver-fire and purge fire， downbear counterflow and control vomiting， and regulate and balance coldness-warmness and was formed by modifying Zuojin Pill. Conclusion In the treatment of chronic gastritis， Professor Huang Zhengde emphasizes the importance of disease differentiation， syndrome differentiation， and Qi-blood and considers emotion at the same time. Professor Huang Zhengde is good at treating chronic gastritis by regulating Qi and activating blood circulation， strengthening the spleen and eliminating dampness， soothing the liver and harmonizing the stomach， and regulating and balancing coldness-warmness., http://www.100md.com(秧丽双 黄政德 吴若霞 任婷 周乐晴)
〔关键词〕 慢性胃炎;聚类分析;理气活血;健脾祛湿;疏肝和胃;黄政德
〔中图分类号〕R256.3 〔文献标志码〕A 〔文章编号〕doi：10.3969/j.issn.1674-070X.2019.03.015
A Cluster Analysis of Professor Huang Zhengde's Medication Rule in the
Treatment of Chronic Gastritis
YANG Lishuang， HUANG Zhengde*， WU Ruoxia， REN Ting， ZHOU Leqing
(Hunan University of Chinese Medicine， Changsha， Hunan 410208， China)
〔Abstract〕 Objective To investigate the medication rule of Professor Huang Zhengde， an advisor for national traditional Chinese medicine (TCM) experience inheritance work (5th session)， in the treatment of chronic gastritis by a cluster analysis. Methods The clinical data of patients with chronic gastritis who were treated by Professor Huang Zhengde in the outpatient service and achieved marked response were collected， and EXCEL was used to analyze the frequency of TCM prescriptions. The function of highly frequently used TCM herbs was analyzed， and SPSS 21.0 was used to perform the cluster analysis. Results A total of 127 patients with chronic gastritis were enrolled， with 190 outpatient medical records in total. A total of 95 TCM herbs were used， among which 46 were highly frequently used herbs. The 10 most frequently used herbs were Radix Glycyrrhizae， Radix Paeoniae Alba， Saussurea costus， Poria cocos， Rhizoma Pinelliae Praeparatum， tangerine peel， Bupleurum chinense， Rhizoma Ligustici Chuanxiong， Rhizoma Corydalis， and Atractylodes macrocephala. Four clustering prescriptions were obtained. C1 prescription could regulate Qi and activate blood circulation， strengthen the spleen and eliminate dampness， and eliminate abdominal mass and alleviate pain and was formed by modifying Chaihu Shugan Powder and Liujunzi Decoction; C2 prescription could regulate triple energizers， strengthen the spleen， eliminate dampness and abdominal mass， and soothe the liver and resolve stagnation and was formed by modifying Sanren Decoction; C3 prescription could nourish Yin and clear the stomach， strengthen the spleen， activate blood circulation， and alleviate pain， and soothe the liver and resolve stagnation and was formed by modifying Yiguan Decoction; C4 prescription could clear liver-fire and purge fire， downbear counterflow and control vomiting， and regulate and balance coldness-warmness and was formed by modifying Zuojin Pill. Conclusion In the treatment of chronic gastritis， Professor Huang Zhengde emphasizes the importance of disease differentiation， syndrome differentiation， and Qi-blood and considers emotion at the same time. Professor Huang Zhengde is good at treating chronic gastritis by regulating Qi and activating blood circulation， strengthening the spleen and eliminating dampness， soothing the liver and harmonizing the stomach， and regulating and balancing coldness-warmness., http://www.100md.com(秧丽双 黄政德 吴若霞 任婷 周乐晴)
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