排石汤对上尿路结石输尿管软镜碎石术后辅助排石的疗效观察(1)
〔摘要〕 目的 观察排石汤促进上尿路结石患者输尿管软镜碎石术后残余结石排出的临床疗效。方法 将102例输尿管上段结石、肾结石患者随机分为观察组和对照组各51例，两组患者均行输尿管软镜碎石术，观察组患者术后加用中药排石汤辅助治疗2周。于术后第4周、第8周观察两组患者肾绞痛发生率及净石率，同时监测观察组有无药物不良反应。结果 术后观察组肾绞痛发生率为9.8%，对照组为25.5%，两组比较差异具有统计学意义(P<0.05)。观察组术后4周及术后8周的净石率分别为96.1%和98.0%，对照组分别为82.4%和86.3%，两组间比较差异具有统计学意义(P<0.05)。观察组患者服用中药排石汤过程未发生药物相关不良反应。结论 中药排石汤能有效促进上尿路结石患者输尿管软镜碎石术后残余结石的排出，提高净石率，降低肾绞痛的发生率，且无明显不良反应，因而中药排石汤辅助输尿管软镜术后排石有临床推广价值。
〔关键词〕 上尿路结石;排石汤;输尿管软镜碎石术;临床疗效
〔中图分类号〕R256.52 〔文献标志码〕B 〔文章编号〕doi：10.3969/j.issn.1674-070X.2020.08.017
〔Abstract〕 Objective To observe the clinical efficacy of Paishi Decoction in the treatment of residual calculi removal for patients with upper urinary stone after flexible ureteroscopic lithotripsy. Methods A total of 102 patients with upper ureteral stones or kidney stones were randomly divided into 51 cases in the observation group and 51 cases in the control group， and the patients in both groups were treated with flexible ureteroscopic lithotripsy. Patients in the observation group were add Chinese medicine Paishi Decoction for 2 weeks after surgery. The incidence of renal colic and the rate of stone clearance were observed at the 4th week and the 8th week after operation. At the same time， the observation group was monitored for adverse drug reactions. Results The incidence of renal colic was 9.8% in the observation group， and 25.5% in the control group. The difference between the 2 groups was statistically significant (P<0.05). The stone removal rate in the observation group at 4 weeks and 8 weeks after operation were 96.1% and 98.0%， and that in the control group were 82.4% and 86.3%， respectively. The difference was statistically significant (P<0.05). There were no drug-related adverse reactions in the observation group after taking Chinese medicine Paishi Decoction. Conclusion Chinese medicine Paishi Decoction can effectively promote the removal of stone fragments for patients with upper urinary stone after flexible ureteroscopic lithotripsy， improve the stone-cleaning rate and reduce the incidence of renal colic. The treatment has no obvious adverse reactions， so the Chinese medicine Paishi Decoction assists calculi removal after flexible ureteroscopic lithotripsy has value for clinical promotion.
〔Keywords〕 upper urinary stone; Paishi Decoction; flexible ureteroscopic lithotripsy; clinical observation
泌尿系結石是我国泌尿外科最常见疾病之一，居泌尿外科住院病人首位。随着生活水平日益提高，上尿路结石的发病率近年来有增高趋势。输尿管软镜处理上尿路结石具有疗效确切、创伤小、恢复快等优点，应用越来越广[1]。但越来越多的研究发现输尿管软镜处理上尿路结石后，存在体内残留结石短期内无法排净的缺点，残余结石成为新的结石核心，引起结石复发，造成输尿管再次梗阻、疼痛等症状的发生[2]。为此，我们对行输尿管软镜治疗的上尿路结石患者加用中药排石汤辅助术后排石治疗，取得了较好的临床疗效，提高了术后净石率，现将研究结果报道如下。, http://www.100md.com(刘剑 王婷 邓光程)
〔关键词〕 上尿路结石;排石汤;输尿管软镜碎石术;临床疗效
〔中图分类号〕R256.52 〔文献标志码〕B 〔文章编号〕doi：10.3969/j.issn.1674-070X.2020.08.017
〔Abstract〕 Objective To observe the clinical efficacy of Paishi Decoction in the treatment of residual calculi removal for patients with upper urinary stone after flexible ureteroscopic lithotripsy. Methods A total of 102 patients with upper ureteral stones or kidney stones were randomly divided into 51 cases in the observation group and 51 cases in the control group， and the patients in both groups were treated with flexible ureteroscopic lithotripsy. Patients in the observation group were add Chinese medicine Paishi Decoction for 2 weeks after surgery. The incidence of renal colic and the rate of stone clearance were observed at the 4th week and the 8th week after operation. At the same time， the observation group was monitored for adverse drug reactions. Results The incidence of renal colic was 9.8% in the observation group， and 25.5% in the control group. The difference between the 2 groups was statistically significant (P<0.05). The stone removal rate in the observation group at 4 weeks and 8 weeks after operation were 96.1% and 98.0%， and that in the control group were 82.4% and 86.3%， respectively. The difference was statistically significant (P<0.05). There were no drug-related adverse reactions in the observation group after taking Chinese medicine Paishi Decoction. Conclusion Chinese medicine Paishi Decoction can effectively promote the removal of stone fragments for patients with upper urinary stone after flexible ureteroscopic lithotripsy， improve the stone-cleaning rate and reduce the incidence of renal colic. The treatment has no obvious adverse reactions， so the Chinese medicine Paishi Decoction assists calculi removal after flexible ureteroscopic lithotripsy has value for clinical promotion.
〔Keywords〕 upper urinary stone; Paishi Decoction; flexible ureteroscopic lithotripsy; clinical observation
泌尿系結石是我国泌尿外科最常见疾病之一，居泌尿外科住院病人首位。随着生活水平日益提高，上尿路结石的发病率近年来有增高趋势。输尿管软镜处理上尿路结石具有疗效确切、创伤小、恢复快等优点，应用越来越广[1]。但越来越多的研究发现输尿管软镜处理上尿路结石后，存在体内残留结石短期内无法排净的缺点，残余结石成为新的结石核心，引起结石复发，造成输尿管再次梗阻、疼痛等症状的发生[2]。为此，我们对行输尿管软镜治疗的上尿路结石患者加用中药排石汤辅助术后排石治疗，取得了较好的临床疗效，提高了术后净石率，现将研究结果报道如下。, http://www.100md.com(刘剑 王婷 邓光程)