血脂和维生素E含量变化测定在诊断妊高征中的临床研究
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【摘要】 目的测定妊高征患者血和新生儿脐血血清中TC、TG、HDL-C、LDL-C和维生素E(VitE)的含量水平并探讨其在妊高征发病中的作用。方法分别用蛋白酶法和比色法测定74例正常孕妇和脐血及69例妊高征(分为妊娠高血压组和轻重度先兆子痫组)孕妇和脐血血清中TC、TG、HDL-C、LDL-C和维生素E(VitE)的含量水平。结果妊娠高血压组、轻重度先兆子痫组较正常孕妇TC、TG和LDL-C含量明显升高(P<0.05,P<0.05),HDL-C和维生素E(VitE)含量则较正常孕妇明显降低(P<0.05,P<0.05),轻重度先兆子痫组与妊娠高血压组间各指标有显著差异(P<0.05)。结论结果提示血脂和维生素E含量的改变对妊高征发生发展起重要作用。
【关键词】 妊高征维生素E脂类代谢
【中图分类号】 R714【文献标识码】 A【文章编号】 1674-0742(2011)06(a)-0017-02
The clinical study of determining content changes of lipid and vitamin E in diagnosis of PIH
【Abstract】 ObjectiveTo determine the levels of serum TC、TG、HDL-C、LDL-C and vitamin E(VitE) in the pregnancy-induced hypertension and neonatal cord bloodand their roles in the pathogenesis of preeclampsia.MethodsThe levels of TC、TG、HDL-C、LDL-C were determined by protease method in 74 normal pregnant women and cord blood and 69 cases(including pregnancy-induced hypertension mild and severe pre-eclampsia group) of pregnancy induced hypertension and umbilical cord blood,vitamin E (VitE)was determined by Colorimetric method ......
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