利尿剂与ACEI联合应用治疗轻中度原发性高血压的疗效评价
,缬沙坦依那普利氢氯噻嗪原发性高血压
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【摘要】 目的评估利尿剂(氢氯噻嗪)与ACEI(血管紧张素转化酶抑制剂)联合应用治疗轻中度原发性高血压的疗效。方法180例原发性高血压患者随机分为A、B2组,A组接受依那普利10mg+氢氯噻嗪10mg,1次/d,B组接受缬沙坦80mg+氢氯噻嗪10mg,1次/d,治疗8周复查疗效。结果动态血压监测结果显示,2组治疗后24h平均收缩压、舒张压均显著降低(P<0.001)。但A组血压降低效果较B组明显。结论依那普利+氢氯噻嗪的降压效果优于缬沙坦+氢氯噻嗪。
【关键词】 缬沙坦依那普利氢氯噻嗪原发性高血压
【中图分类号】 R544【文献标识码】 A【文章编号】 1674-0742(2011)07(b)-0008-02
To Assess the Efficacy of Combination with Diuretic and ACEI to Treatment Mild and Moderate Essential Hypertension
Zhou JianjunZHANG Jiuning
Maternal and Child Health Station Jingtai County Baiyin City,Gansu 730400,China
【Abstract】 ObjectiveTo assess the efficacy Of enalapril+hydrochlorothiazide and valsartan+hydrochlorothiazide in patients with mild and moderate primary hypertension.Methods180 patients with primary hypertension were randomly divided into A,B groups,A group received enalapril 10mg+Hydrochlorothiazide 10mg,1 times/day,B group received valsartan 80mg+Hydrochlorothiazide 10mg,1 times/day,Evaluation of efficacy of treatment for 8 weeks ......
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