瑞舒伐他汀与阿托伐他汀的降脂效果对比观察(2)
综上所述,对比两种他汀类药物,同为较低剂量组,瑞舒伐他汀在降低低密度脂蛋白胆固醇效果上幅度及速度更胜一筹,安全性方面也优于阿托伐他汀,是值得推广的新型他汀类降血脂药物。
[参考文献]
[1] Okazaki S,Yokoyama T,Miyauchi K, et al. Early statin treatment in patients with acute coronary syndrome:demonstration of the beneficial effect on atherosclerotic lesions by serial volumetric intravascular ultrasound analysis during half a year after coronary event:the establish Study[J].Circulation,2004,110:1061-1068.
[2] Tall L,Berk L,TAN S,et al.Combined effects of rosuvastatin and pilglitazone in attenuating interferon gamma,tumor necrosis factoralpha,interleukin·6,Creactive protein,and increasing interleukin-4 may provide cardioprotection for patients with diabetes[J].Chest Supplement,2006, 130(4):191.
[3] 范书英,王勇.强化他汀与联合降脂:降脂幅度相同,获益却不同[J].中国全科医学,2012,15(5B):1554-1555.
[4] Ridker PM, Rifai N, Pfeffer MA, et al.Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events(CARE) Investigators[J].Circulation,1998,98:839-844.
[5] 王素云,王海芸,黄晓燕,等.阿托伐他汀对大鼠缺血心肌TRAIL表达及细胞凋亡的影响[J].温州医学院院报,2012,42(4):317-321.
(收稿日期:2013-03-23), 百拇医药(郑铎 郭文娟)
[参考文献]
[1] Okazaki S,Yokoyama T,Miyauchi K, et al. Early statin treatment in patients with acute coronary syndrome:demonstration of the beneficial effect on atherosclerotic lesions by serial volumetric intravascular ultrasound analysis during half a year after coronary event:the establish Study[J].Circulation,2004,110:1061-1068.
[2] Tall L,Berk L,TAN S,et al.Combined effects of rosuvastatin and pilglitazone in attenuating interferon gamma,tumor necrosis factoralpha,interleukin·6,Creactive protein,and increasing interleukin-4 may provide cardioprotection for patients with diabetes[J].Chest Supplement,2006, 130(4):191.
[3] 范书英,王勇.强化他汀与联合降脂:降脂幅度相同,获益却不同[J].中国全科医学,2012,15(5B):1554-1555.
[4] Ridker PM, Rifai N, Pfeffer MA, et al.Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events(CARE) Investigators[J].Circulation,1998,98:839-844.
[5] 王素云,王海芸,黄晓燕,等.阿托伐他汀对大鼠缺血心肌TRAIL表达及细胞凋亡的影响[J].温州医学院院报,2012,42(4):317-321.
(收稿日期:2013-03-23), 百拇医药(郑铎 郭文娟)