肾脏疾病患者的骨密度变化(1)
[摘要]目的 探讨肾脏疾病患者的骨密度变化情况。方法 应用具有丰富经验和专业知识的临床检验人员进行研究组肾脏疾病患者和对照组健康人群骨密度检测工作，记录两组骨密度检测结果，分析不同肾小球滤过率对骨密度影响效果，通过统计分析获得结论。结果 通过研究组肾脏疾病病人与对照组健康人群临床资料分析可知，研究组骨密度显著低于对照组；对比五组肾脏疾病患者骨密度可知，A组骨密度最高而E组骨密度最低，即肾功能越差则骨密度越低，对比结果差异有统计学意义(P<0.05)。结论 肾脏疾病患者骨质疏松发生率将显著增加，临床医生应准确掌握肾脏疾病与骨密度相关性特征，对骨质疏松高危人群提供针对性的干预措施，有效缓解肾脏疾病患者骨密度下降速度，减少其骨质疏松发生率，保障患者生活质量及生命安全。
[关键词]肾脏疾病；骨密度；变化
[中图分类号]R692.3 [文献标识码]A [文章编号]1674-0742(2015)04(b)-0033-02
Changes in Bone Mineral Density in Patients with Kidney Disease
ZHU Qiaohong
Renal Department of Internal Medicine， The First People’s Hospital of Yangzhou City， Yangzhou，Jiangshu Province，225001 China
[Abstract]Objective To investigate the changes of bone mineral density in patients with kidney disease.Methods Clinical Laboratory de signated personnel with expertise and experience in the completion of the study group and the control group in patients with healthy people working kidney disease， bone density testing， recording two bone density test results， analysis of different glomerular filtration rate effect on bone mineral density after giving statistical analysis concluded.Results The patients in the control group of healthy people with clinical data analysis shows that kidney disease study group， bone density study group was significantly lower than the control group； comparing five groups of bone mineral density in patients with known kidney disease， A group of the highest bone mineral density lowest group E，suggesting that bone mineral density was positively correlated with the glomerular filtration rate， renal function， the worse is that the lower bone density， comparing the results were statistically significant (P<0.05).Conclusion The incidence of osteoporosis in patients with kidney disease will increase significantly， clinicians should accurately grasp kidney disease associated with bone mineral density characteristics， providing targeted interventions for osteoporosis risk populations， effectively alleviate the rate of decline in bone mineral density in patients with kidney disease reduce their incidence of osteoporosis， quality of life and protect the lives and safety of patients.
[Key words]Kidney disease； Bone density；Changes
肾脏疾病是临床常见病及多发病，患者大多伴有机体骨代谢及矿物质紊乱等异常情况，严重影响病人的生活质量和生命安全 [1]。选取2010年5月1日—2013年12月31日期间前来该院就诊的100例肾脏疾病患者进行临床研究，探究肾脏疾病患者的骨密度变化情况，为保障患者的生活质量及生命安全提供有力保障，现报道如下。
1 资料与方法
1.1 一般资料
所有研究对象中有47例男性、53例女性，年龄19～87岁，平均年龄(42.92±2.87)岁，疾病类型：慢性肾小球肾炎53例、梗阻性肾病2例、糖尿病肾病14例、高血压肾动脉硬化20例、多囊肾病11例。同时选取100例前来该院实施体检的健康人群为对照组，其中包括48例男性和52例女性，年龄18～85岁，平均年龄(44.08±2.79)岁。研究组肾脏疾病患者与对照组健康人群性别、年龄、例数等一般资料相比，差异无统计学意义(P>0.05)，具有可比性。, 百拇医药(朱巧红)
[关键词]肾脏疾病；骨密度；变化
[中图分类号]R692.3 [文献标识码]A [文章编号]1674-0742(2015)04(b)-0033-02
Changes in Bone Mineral Density in Patients with Kidney Disease
ZHU Qiaohong
Renal Department of Internal Medicine， The First People’s Hospital of Yangzhou City， Yangzhou，Jiangshu Province，225001 China
[Abstract]Objective To investigate the changes of bone mineral density in patients with kidney disease.Methods Clinical Laboratory de signated personnel with expertise and experience in the completion of the study group and the control group in patients with healthy people working kidney disease， bone density testing， recording two bone density test results， analysis of different glomerular filtration rate effect on bone mineral density after giving statistical analysis concluded.Results The patients in the control group of healthy people with clinical data analysis shows that kidney disease study group， bone density study group was significantly lower than the control group； comparing five groups of bone mineral density in patients with known kidney disease， A group of the highest bone mineral density lowest group E，suggesting that bone mineral density was positively correlated with the glomerular filtration rate， renal function， the worse is that the lower bone density， comparing the results were statistically significant (P<0.05).Conclusion The incidence of osteoporosis in patients with kidney disease will increase significantly， clinicians should accurately grasp kidney disease associated with bone mineral density characteristics， providing targeted interventions for osteoporosis risk populations， effectively alleviate the rate of decline in bone mineral density in patients with kidney disease reduce their incidence of osteoporosis， quality of life and protect the lives and safety of patients.
[Key words]Kidney disease； Bone density；Changes
肾脏疾病是临床常见病及多发病，患者大多伴有机体骨代谢及矿物质紊乱等异常情况，严重影响病人的生活质量和生命安全 [1]。选取2010年5月1日—2013年12月31日期间前来该院就诊的100例肾脏疾病患者进行临床研究，探究肾脏疾病患者的骨密度变化情况，为保障患者的生活质量及生命安全提供有力保障，现报道如下。
1 资料与方法
1.1 一般资料
所有研究对象中有47例男性、53例女性，年龄19～87岁，平均年龄(42.92±2.87)岁，疾病类型：慢性肾小球肾炎53例、梗阻性肾病2例、糖尿病肾病14例、高血压肾动脉硬化20例、多囊肾病11例。同时选取100例前来该院实施体检的健康人群为对照组，其中包括48例男性和52例女性，年龄18～85岁，平均年龄(44.08±2.79)岁。研究组肾脏疾病患者与对照组健康人群性别、年龄、例数等一般资料相比，差异无统计学意义(P>0.05)，具有可比性。, 百拇医药(朱巧红)