[摘要]重症急性胰腺炎病情进展迅速、病死率高。能否通过早期预防性使用抗生素来减少患者病死率仍争议不断。随着医疗技术的发展，预防性使用抗生素的途径增多，通过不同途径预防性使用抗生素的疗效不同。本文从静脉滴注、持续动脉灌注、腹腔灌洗途径阐述了目前重症急性胰腺炎中预防性使用抗生素的现状。

    [关键词]重症急性胰腺炎；预防性抗生素；持续区域动脉灌注；腹腔灌洗

    [中图分类号]R473.6 [文献标识码]A [文章编号]1674-0742(2015)04(b)-0093-03

    Severe Acute Pancreatitis of Different Ways of Using Antibiotic Prophylaxis

    LIU Shunhai LIU Zuojin

    (The second affiliated hospital of Chongqing medical university，Chongqing 400010 China

    [Abstract]Sever acute pancreatitis (SAP) progresses quickly and has a high mortality. It is still controversial to decrease the death rate through prophylactic antibiotics. With the development of the medical technique ......