[摘要] 目的 研究溶栓(尿激酶)联合抗凝(低分子肝素)治疗下肢深静脉血栓的临床效果。方法 将整群抽取的该院收治的84例下肢深静脉血栓患者抽签随机分为研究组(42例)与对照组(42例)，均采取低分子肝素抗凝治疗，研究组另给予尿激酶溶栓治疗，治疗14 d后比较两组临床疗效及患肢髌缘上下5 cm周径差变化。结果 研究组治疗总有效率97.62% VS 78.57%显著较高(P<0.05)；研究组髌缘上5 cm周径差及髌缘下5 cm周径差分别为(2.68±1.84)cm、(2.84±1.97)cm VS 对照组(4.12±2.81)cm、(4.35±3.03)cm显著较低，对比差异有统计学意义(P<0.05)。结论 尿激酶溶栓治疗联合低分子肝素抗凝治疗下肢深静脉效果显著，优于单一抗凝治疗，具有较高的临床应用价值。

    [关键词] 溶栓；抗凝；下肢深静脉血栓

    [中图分类号] R654.4 [文献标识码] A [文章编号] 1674-0742(2015)04(c)-0119-02

    [Abstract] Objective To study the clinical effect of thrombolytic (urokinase) combined with anticoagulation (low molecular weight heparin) in the treatment of lower extremity deep venous thrombosis. Methods 84 cases of lower extremity deep venous thrombosis patients were randomly divided into study group (42 cases) and control group (42 cases) ......