血必净注射液治疗创伤后急性肺损伤的疗效分析(1)
[摘要] 目的 对血必净注射液治疗创伤后急性肺损伤的疗效进行研究分析。 方法 从该院2011年3月—2014年10月创伤后急性肺损伤患者中整群选取68例，分为治疗组和对照组，均为34例，对采用不同治疗方法治疗患者的临床治疗效果进行对比。结果 治疗组患者临床治疗总有效率为91.18%、呼吸窘迫综合征发生率20.59%、死亡率为8.82%同对照组患者的58.82%、41.18%和26.47%相比，P<0.05；对比两组患者治疗前RR、PaO2和PaO2/FiO2，P>0.05；实施临床治疗后，两组患者同治疗前之间差异有统计学意义，且治疗组患者同对照组患者之间差异有统计学意义，P<0.05。结论 在治疗创伤后急性肺损伤疾病临床上血必净注射液临床效果较为理想，有效改善患者呼吸功能。
[关键词] 血必净注射液；创伤后急性肺损伤；临床效果
[中图分类号] R641 [文献标识码] A [文章编号] 1674-0742(2015)06(c)-0140-02
[Abstract] Objective To study the curative effect of xuebijing injection in the treatment of post-traumatic acute lung injury. Methods 68 patients with post-traumatic acute lung injury treated in our hospital between March 2011 and October 2014 were selected and divided into treatment group and control group， 34 in each group. Clinical therapeutic effects of the two groups by different treatment methods were compared. Results The clinical total effective rate， incidence of respiratory distress syndrome， mortality rate of the treatment group were 91.18%， 20.59% and 8.82%， and those of the control group were 58.82%， 41.18% and 58.82%， and the difference between the two groups were statistically significant， P < 0.05； there were not statistically significant differences between the RR， PaO2 and PaO2 / FiO2 of the two groups before treatment， P > 0.05， while after the treatment， there were statistically significant differences between RR， PaO2 and PaO2 / FiO2 of the two groups before treatment and those after treatment， as well as between those of the treatment group and the control group， P < 0.05. Conclusion In the treatment of post-traumatic acute lung injury， the clinical effect of xuebijing injection is ideal and it can effectively improve patients’ respiratory function.
[Key words] Xuebijing injection； Post-traumatic acute lung injury； Clinical effect
临床上，急性肺损伤疾病主要因患者机体遭受严重创伤、感染、酸中毒、休克和有害气体等因素打击后，导致患者弥漫性肺泡—毛细血管膜受损产生的微肺不张和肺水肿等病理特征，顽固性低氧血症和呼吸窘迫等为该疾病的主要临床症状。为进一步了解血必净注射液治疗创伤后急性肺损伤的疗效进行研究分析，现报道如下。
1 资料与方法
1.1 一般资料
整群选取该院在2011年3月—2014年10月收治的68例创伤后急性肺损伤患者，其中，治疗组34例，男22例，女12例；患者年龄为15～68岁，平均年龄(41.51±1.14)岁；对照组34例，男23例，女11例；患者年龄为16～69岁，平均年龄(42.11±1.32)岁。对该研究选取患者的年龄、性别等基本资料展开对比分析，P>0.05，可对比。
1.2 方法
1.2.1 对照组 患者通过常规临床治疗方法治疗，医护人员通过抗炎、氧疗、联合抗生素、激素等对症治疗方法治疗。对于部分每分钟呼吸频率>28次、每分钟氧流量>6 L、动脉血氧分压低于55 mmHg的患者应通过鼻罩无创机械通气进行治疗，对其进行为期7 d的观察。
1.2.2 治疗组 患者在对照组患者治疗基础上加以血必净注射液治疗，患者除通过抗炎、氧疗、联合抗生素、激素等对症治疗方法治疗之外，静脉滴注2次/d由天津红日药业股份有限公司生产的、批号为Z20040033的100 mL血必净注射液+100 mL5%葡萄糖液进行治疗。, http://www.100md.com(盛洁莹)
[关键词] 血必净注射液；创伤后急性肺损伤；临床效果
[中图分类号] R641 [文献标识码] A [文章编号] 1674-0742(2015)06(c)-0140-02
[Abstract] Objective To study the curative effect of xuebijing injection in the treatment of post-traumatic acute lung injury. Methods 68 patients with post-traumatic acute lung injury treated in our hospital between March 2011 and October 2014 were selected and divided into treatment group and control group， 34 in each group. Clinical therapeutic effects of the two groups by different treatment methods were compared. Results The clinical total effective rate， incidence of respiratory distress syndrome， mortality rate of the treatment group were 91.18%， 20.59% and 8.82%， and those of the control group were 58.82%， 41.18% and 58.82%， and the difference between the two groups were statistically significant， P < 0.05； there were not statistically significant differences between the RR， PaO2 and PaO2 / FiO2 of the two groups before treatment， P > 0.05， while after the treatment， there were statistically significant differences between RR， PaO2 and PaO2 / FiO2 of the two groups before treatment and those after treatment， as well as between those of the treatment group and the control group， P < 0.05. Conclusion In the treatment of post-traumatic acute lung injury， the clinical effect of xuebijing injection is ideal and it can effectively improve patients’ respiratory function.
[Key words] Xuebijing injection； Post-traumatic acute lung injury； Clinical effect
临床上，急性肺损伤疾病主要因患者机体遭受严重创伤、感染、酸中毒、休克和有害气体等因素打击后，导致患者弥漫性肺泡—毛细血管膜受损产生的微肺不张和肺水肿等病理特征，顽固性低氧血症和呼吸窘迫等为该疾病的主要临床症状。为进一步了解血必净注射液治疗创伤后急性肺损伤的疗效进行研究分析，现报道如下。
1 资料与方法
1.1 一般资料
整群选取该院在2011年3月—2014年10月收治的68例创伤后急性肺损伤患者，其中，治疗组34例，男22例，女12例；患者年龄为15～68岁，平均年龄(41.51±1.14)岁；对照组34例，男23例，女11例；患者年龄为16～69岁，平均年龄(42.11±1.32)岁。对该研究选取患者的年龄、性别等基本资料展开对比分析，P>0.05，可对比。
1.2 方法
1.2.1 对照组 患者通过常规临床治疗方法治疗，医护人员通过抗炎、氧疗、联合抗生素、激素等对症治疗方法治疗。对于部分每分钟呼吸频率>28次、每分钟氧流量>6 L、动脉血氧分压低于55 mmHg的患者应通过鼻罩无创机械通气进行治疗，对其进行为期7 d的观察。
1.2.2 治疗组 患者在对照组患者治疗基础上加以血必净注射液治疗，患者除通过抗炎、氧疗、联合抗生素、激素等对症治疗方法治疗之外，静脉滴注2次/d由天津红日药业股份有限公司生产的、批号为Z20040033的100 mL血必净注射液+100 mL5%葡萄糖液进行治疗。, http://www.100md.com(盛洁莹)
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