RVVC患者与VVC患者的流行病学研究(1)
[摘要] 目的 探讨VVC(外阴阴道念珠菌病)患者同RVVC(复发性VVC)患者的流行病学特点。 方法 整群选择该院2014年5月—2015年5月就诊患者12 365例，针对所有患者实施阴道分泌物真菌学镜检。在该研究的12 365例患者中。患有VVC疾病的患者例数为500例(4.04%)；表现出RVVC患者例数为30例(0.24%)。针对VVC患者以及RVVC患者认真实施调查登记以及相关分析。 结果 针对RVVC患者同VVC患者二者之间进行比较发现，在选择激素、选择抗生素、选择避孕药、实施替代治疗以及个人卫生习惯方面，差异无统计学意义(P>0.05)，分析出现RVVC的情况同患者表现出局部免疫异常具有密切的关系。针对以往用药进行分析发现，RVVC患者同VVC患者之间，差异无统计学意义(P>0.05)。 结论 患者患有VVC疾病或者表现出RVVC的情况后，针对患者的身心健康会造成严重的威胁。患者出现RVVC同患者出现局部免疫异常表现出一定的关联，对此针对RVVC患者，需要合理选择敏感抗真菌药物进行治疗，并且需要实施疗程巩固。
[关键词] RVVC；VVC；流行病学研究
[中图分类号] R711.3 [文献标识码] A [文章编号] 1674-0742(2016)02(b)-0055-03
[Abstract] Objective To discuss the characteristics of epidemiology of RVVC (recurrent vulvar vaginal candidiasis) patients and VVC (vulvar vaginal candidiasis) patients. Methods 12365 cases of patients treated in our hospital from May 2014 to May 2015 were selected and all patients were given vaginal discharge mycology microscopy， 500 cases of patients were with VVC in this study (4.04%)， among them， 30 cases were with RVVC(0.24%)， the VVC patients and RVVC patients were carefully investigated and registered and given related analysis. Results The differences in the hormone choice， antibiotic choice， acyeterion choice， implementation of replacement therapy and personal hygiene custom between RVVC patients and VVC patients were not obvious(P>0.05)， the occurrence of RVVC had a close relationship with the local immune abnormalities that patients showed， the difference in the previous drug-taking between the RVVC patients and VVC patients was not obvious(P>0.05). Conclusion The VVC disease or RVVC situation can pose a serious threat to the patient’s physical and mental health， the occurrence of RVVC in patients has a certain relationship with the local immune abnormalities that patients show， therefore， we need rationally choose sensitive antifungal agents to treat RVVC patients and also need implement the consolidation of the course of treatment.
[Key words] RVVC； VVC； Epidemiology Research
VVC属于较为普遍的一种妇女外阴阴道炎症，疾病复发主要指的是针对此类患者实施临床治疗后，患者的临床症状以及临床体征表现全部消失，对患者实施真菌学检查最终表现出阴性，之后患者又表现出相关症状，对患者实施真菌检查最终表现为阳性[1]。患者在1年内疾病发作的次数不小于4次，则证明患者出现了RVVC的情况。针对RVVC疾病虽然出现的概率较低，但是因为表现出经常发作的特点，针对妇女的身心健康会造成严重的影响[2]。为了对VVC以及RVVC二者的流行病学特点进行分析，分析该院2014年5月—2015年5月就诊患者12365例的临床资料，现报道如下。
1 资料与方法
1.1 一般资料
整群选择该院就诊患者12 365例为研究对象。年龄范围为23～45岁，平均年龄为(32.5±1.6)岁；经过临床研究发现，患有VVC疾病的患者例数为500例(4.04%)；表现出RVVC患者例数为30例(0.24%)。VVC组：患者共计500例，患者年龄范围为21～47岁，患者平均年龄为(36.3±1.3)岁。其中，严重患者共计102例，中度患者共计106例，轻度患者共计292例。RVVC组：患者共计30例，患者年龄范围为22～48岁，患者平均年龄为(36.4±1.7)岁。其中，严重患者共计2例，中度患者共计10例，轻度患者共计18例。 (柯珣瑜 曾晓惠)
[关键词] RVVC；VVC；流行病学研究
[中图分类号] R711.3 [文献标识码] A [文章编号] 1674-0742(2016)02(b)-0055-03
[Abstract] Objective To discuss the characteristics of epidemiology of RVVC (recurrent vulvar vaginal candidiasis) patients and VVC (vulvar vaginal candidiasis) patients. Methods 12365 cases of patients treated in our hospital from May 2014 to May 2015 were selected and all patients were given vaginal discharge mycology microscopy， 500 cases of patients were with VVC in this study (4.04%)， among them， 30 cases were with RVVC(0.24%)， the VVC patients and RVVC patients were carefully investigated and registered and given related analysis. Results The differences in the hormone choice， antibiotic choice， acyeterion choice， implementation of replacement therapy and personal hygiene custom between RVVC patients and VVC patients were not obvious(P>0.05)， the occurrence of RVVC had a close relationship with the local immune abnormalities that patients showed， the difference in the previous drug-taking between the RVVC patients and VVC patients was not obvious(P>0.05). Conclusion The VVC disease or RVVC situation can pose a serious threat to the patient’s physical and mental health， the occurrence of RVVC in patients has a certain relationship with the local immune abnormalities that patients show， therefore， we need rationally choose sensitive antifungal agents to treat RVVC patients and also need implement the consolidation of the course of treatment.
[Key words] RVVC； VVC； Epidemiology Research
VVC属于较为普遍的一种妇女外阴阴道炎症，疾病复发主要指的是针对此类患者实施临床治疗后，患者的临床症状以及临床体征表现全部消失，对患者实施真菌学检查最终表现出阴性，之后患者又表现出相关症状，对患者实施真菌检查最终表现为阳性[1]。患者在1年内疾病发作的次数不小于4次，则证明患者出现了RVVC的情况。针对RVVC疾病虽然出现的概率较低，但是因为表现出经常发作的特点，针对妇女的身心健康会造成严重的影响[2]。为了对VVC以及RVVC二者的流行病学特点进行分析，分析该院2014年5月—2015年5月就诊患者12365例的临床资料，现报道如下。
1 资料与方法
1.1 一般资料
整群选择该院就诊患者12 365例为研究对象。年龄范围为23～45岁，平均年龄为(32.5±1.6)岁；经过临床研究发现，患有VVC疾病的患者例数为500例(4.04%)；表现出RVVC患者例数为30例(0.24%)。VVC组：患者共计500例，患者年龄范围为21～47岁，患者平均年龄为(36.3±1.3)岁。其中，严重患者共计102例，中度患者共计106例，轻度患者共计292例。RVVC组：患者共计30例，患者年龄范围为22～48岁，患者平均年龄为(36.4±1.7)岁。其中，严重患者共计2例，中度患者共计10例，轻度患者共计18例。 (柯珣瑜 曾晓惠)