神经干细胞移植治疗血管性痴呆大鼠的实验研究(1)
[摘要] 目的 研究神经干细胞移植治疗血管性痴呆大鼠的临床效果。方法 选择年龄在12个月左右的60只健康成年Wistar大鼠作为该次实验对象，实验时间为2015年5—10月，大鼠的体重均在300～400 g左右，用于制备血管性痴呆2VO模型，将大鼠随机分成3组，分别为假手术组、对照组及NSCs组，在移植前后对3组大鼠实施Morris水迷测试。结果 移植后5周、10周时，NSCs组大鼠逃避潜伏期(36.85±7.14)、(40.26±8.11)相对于对照组(52.11±6.57)、(54.10±7.16)有了显著的减少，差异有统计学意义(P<0.05)。结论 针对VaD大鼠模型采用神经干细胞移植的效果显著，能有效改善大鼠学习记忆能力。
[关键词] 神经干细胞移植；血管性痴呆；实验研究
[中图分类号] R749.13 [文献标识码] A [文章编号] 1674-0742(2016)04(a)-0056-02
[Abstract] Objective To research the clinical effect of neural stem cells transplantation in treatment of rats with vascular dementia. Methods 60 healthy adult Wistar rats whose weight were between 300～400 g and whose ages were about 12 months were selected as the experimental object ......
您现在查看是摘要页，全文长 3895 字符。
[关键词] 神经干细胞移植；血管性痴呆；实验研究
[中图分类号] R749.13 [文献标识码] A [文章编号] 1674-0742(2016)04(a)-0056-02
[Abstract] Objective To research the clinical effect of neural stem cells transplantation in treatment of rats with vascular dementia. Methods 60 healthy adult Wistar rats whose weight were between 300～400 g and whose ages were about 12 months were selected as the experimental object ......
您现在查看是摘要页，全文长 3895 字符。