参黄洗液坐浴联合神灯照射治疗肛门湿疹的临床观察(1)
[摘要] 目的 探讨参黄洗液坐浴联合神灯照射治疗肛门湿疹的临床疗效。 方法 方便选取并按照国际字母排列将60例肛门湿疹患者随机分为两组，每组各30例，治疗组予参黄洗液联合神灯照射治疗。对照组予以派瑞松外涂治疗。通过观察两组的皮损面积、瘙痒程度及疗效。结果 两组在皮损消退，瘙痒程度均有效，两组治疗后，皮损评分： 治疗组为(0.73±0.58)分，对照组为(1.07±0.58)分，治疗组优于对照组(P=0.032)；两组均能明显减轻患者的瘙痒程度，治疗后两组无差异(P=0.46)；治疗组总有效率为96.67%，对照组总有效率为86.67%，两组之间差异有统计学意义。 结论 参黄洗液联合神灯照射治疗治疗肛门湿疹疗效确切、副作用小 。
[关键词] 肛门湿疹；参黄洗液；神灯照射治疗
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2016)04(a)-0151-03
[Abstract] Objective To observe the clinical curative effect of huangshen lotion hip bath combined with infrared radiation in treatment of eczema ani. Methods 60 cases of patients with eczema ani were randomly divided into two groups with 30 cases in each according to the international alphabetic order， the treatment group were treated with huangshen lotion and infrared radiation， the control group were treated with exterior coating of pevisone， and the psoriasis areas， degrees of pruritus and curative effects of the two groups were observed. Results As far as the extinction of skin lesion and degree of pruritus were concerned， both groups were effective， after treatment， the skin lesion score in the treatment group was better than that in the control group， [(0.73±0.58) vs (1.07±0.58)]， P=0.032， both groups can obviously relieve the degree of pruritus， there was no difference between the two groups after treatment， the total effective rate was 96.67% in the treatment group and 86.67% in the control group， and there was an obvious difference between the two groups. Conclusion Huangshen lotion hip bath combined with infrared radiation in treatment of eczema ani has a definite curative effect and small side effect.
[Key words] Eczema ani； Huangshen lotion； Infrared radiation treatment
肛门湿疹是一种由多种因素引起的局限于肛门及其周围的皮肤性疾病，是一种常见多发的变态反应性炎症性皮肤病。目前，西医主要以止痒等对症处理为主，临床疗效有限。近年来，随着中医药的发展，中医外治法因其不良反应少、效果确切的优势逐渐引起临床医师重视。为此，该研究方便收集2015年1—7月湖南中医药大学第一附属医院肛肠科门诊60例患者作为研究对象，积极探索肛门湿疹的中医外治方法，采用参黄洗液结合神灯照射治疗，取得了较好的疗效，现报道如下。
1 资料与方法
1.1 一般资料
方便选取2015年1—7月湖南中医药大学第一附属医院肛肠科门诊患者60例，按照国际字母排列法随机分为治疗组和对照组。每组各30例。两组男25例，女35例；年龄18～78岁，平均( 48.83±16.23) 岁；病程最长5年，最短1月，平均(30.12±4.19 )月；急性肛门湿疹34例，慢性肛门湿疹26例。2组患者性别、年龄、病程及疾病分型等一般资料比较差异无统计学意义(P>0.05)。该研究经我院伦理委员会批准通过，两组患者均了解此次研究内容且签署了知情同意书。
1.2 诊断标准
参照国家中医药管理局颁布的《中医病证诊断疗效标准》评定[1]。排除标准：①患内分泌疾病、肝肾功能不全及肿瘤患者；②月经期、妊娠或哺乳期妇女；③对本药成分过敏者；④观察期中断治疗者。
1.3 治疗方法
1.3.1 治疗组 参黄洗液由该院制剂科提供(批号：0905 04)，药物组成：苦参30 g 黄柏20 g 地榆20 g黄芩20 g 白芍15 g 山栀子15 g 槟榔10 g大黄10 g等。将上药加水800 mL，用文火煎煮至250 mL， 冷却，置于贮槽内行高温灭菌。125 mL/次兑温开水至1 000 mL坐浴15 min，继之以神灯照射20～30 min。照射方式：仰卧位，双侧大腿分开，神灯置于双侧大腿之间，正对患处，照射灯距约20 cm，皮肤温度保持在40℃为宜。照射期间经常询问患者温度感觉，根据患者的感觉及时调节灯距。2 次/d。治疗2周为1疗程，1个疗程后判定疗效，治疗期间禁忌辛辣刺激及海鲜等发物。 (郑凤萍)
[关键词] 肛门湿疹；参黄洗液；神灯照射治疗
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2016)04(a)-0151-03
[Abstract] Objective To observe the clinical curative effect of huangshen lotion hip bath combined with infrared radiation in treatment of eczema ani. Methods 60 cases of patients with eczema ani were randomly divided into two groups with 30 cases in each according to the international alphabetic order， the treatment group were treated with huangshen lotion and infrared radiation， the control group were treated with exterior coating of pevisone， and the psoriasis areas， degrees of pruritus and curative effects of the two groups were observed. Results As far as the extinction of skin lesion and degree of pruritus were concerned， both groups were effective， after treatment， the skin lesion score in the treatment group was better than that in the control group， [(0.73±0.58) vs (1.07±0.58)]， P=0.032， both groups can obviously relieve the degree of pruritus， there was no difference between the two groups after treatment， the total effective rate was 96.67% in the treatment group and 86.67% in the control group， and there was an obvious difference between the two groups. Conclusion Huangshen lotion hip bath combined with infrared radiation in treatment of eczema ani has a definite curative effect and small side effect.
[Key words] Eczema ani； Huangshen lotion； Infrared radiation treatment
肛门湿疹是一种由多种因素引起的局限于肛门及其周围的皮肤性疾病，是一种常见多发的变态反应性炎症性皮肤病。目前，西医主要以止痒等对症处理为主，临床疗效有限。近年来，随着中医药的发展，中医外治法因其不良反应少、效果确切的优势逐渐引起临床医师重视。为此，该研究方便收集2015年1—7月湖南中医药大学第一附属医院肛肠科门诊60例患者作为研究对象，积极探索肛门湿疹的中医外治方法，采用参黄洗液结合神灯照射治疗，取得了较好的疗效，现报道如下。
1 资料与方法
1.1 一般资料
方便选取2015年1—7月湖南中医药大学第一附属医院肛肠科门诊患者60例，按照国际字母排列法随机分为治疗组和对照组。每组各30例。两组男25例，女35例；年龄18～78岁，平均( 48.83±16.23) 岁；病程最长5年，最短1月，平均(30.12±4.19 )月；急性肛门湿疹34例，慢性肛门湿疹26例。2组患者性别、年龄、病程及疾病分型等一般资料比较差异无统计学意义(P>0.05)。该研究经我院伦理委员会批准通过，两组患者均了解此次研究内容且签署了知情同意书。
1.2 诊断标准
参照国家中医药管理局颁布的《中医病证诊断疗效标准》评定[1]。排除标准：①患内分泌疾病、肝肾功能不全及肿瘤患者；②月经期、妊娠或哺乳期妇女；③对本药成分过敏者；④观察期中断治疗者。
1.3 治疗方法
1.3.1 治疗组 参黄洗液由该院制剂科提供(批号：0905 04)，药物组成：苦参30 g 黄柏20 g 地榆20 g黄芩20 g 白芍15 g 山栀子15 g 槟榔10 g大黄10 g等。将上药加水800 mL，用文火煎煮至250 mL， 冷却，置于贮槽内行高温灭菌。125 mL/次兑温开水至1 000 mL坐浴15 min，继之以神灯照射20～30 min。照射方式：仰卧位，双侧大腿分开，神灯置于双侧大腿之间，正对患处，照射灯距约20 cm，皮肤温度保持在40℃为宜。照射期间经常询问患者温度感觉，根据患者的感觉及时调节灯距。2 次/d。治疗2周为1疗程，1个疗程后判定疗效，治疗期间禁忌辛辣刺激及海鲜等发物。 (郑凤萍)