胸穿置管间断与持续引流联合尿激酶治疗结核性渗出性胸膜炎的对比分析(1)
[摘要] 目的 探讨一次性引流导管胸膜腔穿刺置管间断与持续引流联合尿激酶治疗结核性渗出性胸膜炎的疗效。方法 方便选择在2013年2月—2015年12月期间就诊于该院的符合标准的中-大量结核性渗出性胸膜炎患者共60例，随机分成治疗组(间断引流组)及对照组(持续引流组)，每组30例，在全身抗结核药物化疗的基础上，采用胸膜腔穿刺置管的方法引流胸水，并定期经胸膜腔穿刺置管的引流管胸腔内注入尿激酶，分别进行间断引流与持续引流治疗结核性渗出性胸膜炎，观察两种方法的治疗效果、并发症。结果 治疗组和对照组住院时间分别为(8.77±1.25)、(10.77±1.19) d，引流天数分别为(5.17±0.913)、(5.97±0.765) d，胸水完全消失时间(35.83±2.52)、(44.8±3.178) d，两组在状消失时间差异无统计学意义，两组均无明显并发症，微创的一次性引流管胸膜腔穿刺置管间断引流联合胸腔内注入尿激酶治疗结核性渗出性胸膜炎的疗效方面优于持续引流。 结论 在全身抗结核化疗的基础上，微创的一次性引流管胸膜腔穿刺置管引流联合尿激酶胸腔内注入治疗结核性渗出性胸膜炎操作简单、安全、可行，一次性引流管胸膜腔穿刺置管间断引流联合胸腔内注入尿激酶治疗结核性渗出性胸膜炎疗效优于持续引流。
[关键词] 胸穿置管；持续引流；间断引流；结核性胸膜炎；尿激酶
[中图分类号] R561 [文献标识码] A [文章编号] 1674-0742(2016)07(b)-0092-03
Thoracic Puncture Catheter Intermittent or Continuous Comparative Analysis Combined with Urokinase in Treatment of Tuberculous Pleural Effusion Drainage
XU Guang-yan， BAO Yi-bo
Two Department of respiratory of Affiliated Hospital of Zunyi Medical College， Zunyi， Guizhou Province，563003 China
[Abstract] Objective To observe the disposable catheter pleural cavity puncture drainage catheter intermittent or continuous drainage combined with urokinase in the treatment of tuberculous exadative pleurisy efficacy. Methods Convenient selection sixty patients with pleural effusion were enrolled at Zunyi Medical College affiliated hospital from February 2013 to December 2016. with the standard - a lot of tuberculous exudative pleurisy in patients ， were randomly divided into treatment group (Intermittent drainage group )and control group(continuous drainage group)， 30 cases in each group， on the basis of systemic anti tuberculosis chemotherapy by pleural cavity puncture and set tube drainage of pleural effusion， and regularly by pleural cavity puncture device tube drainage tube of intrapleural injection of urokinase， were interrupted drainage and continuous drainage in the treatment of tuberculous exudative pleurisy were observed the therapeutic effect of two methods， complications. Results The time were (8.77±1.25)d and (10.77±1.19)d at hospital in Intermittent drainage group and continuous drainage group，drainage days were (5.17±0.913)d and (5.97±0.765)d，pleural effusion disappeared completely were(35.83±2.52)d and (44.8±3.178)d. Symptom disappeared had no differently in the two groups and both have no significant complications.The minimally invasive disposable drainage tube pleural cavity puncture catheter drainage combined with intrathoracic injection of urokinase in the treatment of tuberculosis exudative pleurisy efficacy is superior to continuous drainage. Conclusion Based on systemic antituberculosis chemotherapy， minimally invasive disposable drainage tube pleural cavity puncture catheter drainage combined with urokinase intrapleural injection treatment of tuberculous exudative pleurisy operation is simple， safe， feasible.Disposable drainage tube pleural cavity puncture catheter interrupted drainage combined with intrapleural injection of urokinase in the treatment of tuberculosis exudative pleurisy efficacy is better than continuous drainage. (徐光艳 包义波)
[关键词] 胸穿置管；持续引流；间断引流；结核性胸膜炎；尿激酶
[中图分类号] R561 [文献标识码] A [文章编号] 1674-0742(2016)07(b)-0092-03
Thoracic Puncture Catheter Intermittent or Continuous Comparative Analysis Combined with Urokinase in Treatment of Tuberculous Pleural Effusion Drainage
XU Guang-yan， BAO Yi-bo
Two Department of respiratory of Affiliated Hospital of Zunyi Medical College， Zunyi， Guizhou Province，563003 China
[Abstract] Objective To observe the disposable catheter pleural cavity puncture drainage catheter intermittent or continuous drainage combined with urokinase in the treatment of tuberculous exadative pleurisy efficacy. Methods Convenient selection sixty patients with pleural effusion were enrolled at Zunyi Medical College affiliated hospital from February 2013 to December 2016. with the standard - a lot of tuberculous exudative pleurisy in patients ， were randomly divided into treatment group (Intermittent drainage group )and control group(continuous drainage group)， 30 cases in each group， on the basis of systemic anti tuberculosis chemotherapy by pleural cavity puncture and set tube drainage of pleural effusion， and regularly by pleural cavity puncture device tube drainage tube of intrapleural injection of urokinase， were interrupted drainage and continuous drainage in the treatment of tuberculous exudative pleurisy were observed the therapeutic effect of two methods， complications. Results The time were (8.77±1.25)d and (10.77±1.19)d at hospital in Intermittent drainage group and continuous drainage group，drainage days were (5.17±0.913)d and (5.97±0.765)d，pleural effusion disappeared completely were(35.83±2.52)d and (44.8±3.178)d. Symptom disappeared had no differently in the two groups and both have no significant complications.The minimally invasive disposable drainage tube pleural cavity puncture catheter drainage combined with intrathoracic injection of urokinase in the treatment of tuberculosis exudative pleurisy efficacy is superior to continuous drainage. Conclusion Based on systemic antituberculosis chemotherapy， minimally invasive disposable drainage tube pleural cavity puncture catheter drainage combined with urokinase intrapleural injection treatment of tuberculous exudative pleurisy operation is simple， safe， feasible.Disposable drainage tube pleural cavity puncture catheter interrupted drainage combined with intrapleural injection of urokinase in the treatment of tuberculosis exudative pleurisy efficacy is better than continuous drainage. (徐光艳 包义波)