头孢他啶联合左氧氟沙星治疗心力衰竭患者肺部感染效果分析(1)
[摘要] 目的 分析头孢他啶联合左氧氟沙星在治疗心力衰竭患者肺部感染的疗效。 方法 方便选取该院2014年6月—2015年11月期间收治的符合心力衰竭肺部感染诊断患者60例,根据随机数表法将患者随机分为两组,每组30例,对照组采用左氧氟沙星治疗,观察组在对照组基础上加用头孢他啶治疗,比较两组治疗效果及治疗后细菌清除率。结果观察组有效率为90.0%明显高于对照组63.3%,差异有统计学意义(P<0.05);观察组细菌清除率74.1%显著高于对照组46.0%,差异有统计学意义(P<0.05)。结论 头孢他啶联合左氧氟沙星治疗心力衰竭患者肺部感染效果显著,在临床应用中值得推广。
[关键词] 头孢他啶;左氧氟沙星;心力衰竭;肺部感染
[中图分类号] R541 [文献标识码] A [文章编号] 1674-0742(2016)07(c)-0152-03
[Abstract] Objective To analyze effect observation of pulmonary infection of the patients with cardiac failure treated by ceftazidime united levofloxacin. Methods To selected 60 cases of patients conformed the cardiac failure received and cured at our hospital from the May 2014 to January 2015. According to a random number table method were randomly divided into two groups of 30 patients in the control group received levofloxacin treatment, observation group was treated with ceftazidime treatment in the control group, based on the two groups were compared after treatment and the treatment of bacterial clearance. Results Observation group was 90.0%, significantly higher than 63.3%, the difference was significant (P <0.05); observation group was 74.1% bacterial clearance rate was significantly higher than 46.0%, the difference was significant (P <0.05). Conclusion That has significant effect of pulmonary infection of the patients with cardiac failure treated by ceftazidime united levofloxacin, and that is worth for promotion in the clinical application.
[Key words] Ceftazidime; Levofloxacin; Cardiac failure; Pulmonary infection
心力衰竭指心脏收缩功能和舒张功能发生障碍,不能够很好的将静脉血排除心脏外,造成静脉血液淤积,引起心脏循环障碍,临床表现为肺部淤血、呼吸困难等症状[1]。研究表明[2-3],所有的心血管疾病最终会导致心力衰竭、心肌梗死、心肌病等心脏疾病的发生,且均以左心室衰竭开始,主要表现为肺循环淤血,容易导致肺部感染,加重心力衰竭,威胁患者的生命。该研究方便选取2014年6月—2015年11月该院收治的60例心力衰竭患者采用头孢他啶联合左氧氟沙星治疗,分析其治疗疗效,现报道如下。
1 资料与方法
1.1 一般资料
方便选取该院收治的符合心力衰竭肺部感染诊断患者60例,将所有患者随机分为两组,观察组30例,男14例,女16例,年龄30-68岁,平均年龄(58.2±2.7)岁。对照组30例,男16例,女14例,年龄35~75岁,平均年龄(62.3±2.2)岁。两组患者的年龄、性别等一般资料比较,差异无统计学意义(P>0.05),具有可比性,且所有患者通过伦理委员会的批准。
1.2 方法
患者入院时均要求卧床休息,严密监测患者的生命体征,并严格控制患者食用钠盐。给予对照组患者静脉注射左氧氟沙星(扬子江药业集团有限公司,国药准字H20143200,生产批号20140304),将0.4 g左氧氟沙星混合250 mL葡萄糖注射液中,1次/d,7~14 d为1个疗程;观察组在对照组基础上加用头孢他啶(国药准字H20033816)治疗,将2.0 g头孢他啶混合150 mL生理盐水中静脉滴注,2次/d,7~14 d为1个疗程。
1.3 观察指标
对比分析两组患者治疗疗效及治疗后细菌清除率。
1.4 判定标准
疗效判定[4]:①显效:肺部感染全部消失,心脏功能恢复正常;②有效:肺部感染基本消失,心脏功能得到缓解,患者临床症状较治疗前有所改善;③无效:肺部感染依旧存在,患者病情并未缓解。
1.5 统计方法
通过SPSS 20.0统计学软件对数据进行分析,用[n(%)]表示计数资料,使用χ2检验,P<0.05时差异有统计学意义。 (吐尔逊那依·斯马依)
[关键词] 头孢他啶;左氧氟沙星;心力衰竭;肺部感染
[中图分类号] R541 [文献标识码] A [文章编号] 1674-0742(2016)07(c)-0152-03
[Abstract] Objective To analyze effect observation of pulmonary infection of the patients with cardiac failure treated by ceftazidime united levofloxacin. Methods To selected 60 cases of patients conformed the cardiac failure received and cured at our hospital from the May 2014 to January 2015. According to a random number table method were randomly divided into two groups of 30 patients in the control group received levofloxacin treatment, observation group was treated with ceftazidime treatment in the control group, based on the two groups were compared after treatment and the treatment of bacterial clearance. Results Observation group was 90.0%, significantly higher than 63.3%, the difference was significant (P <0.05); observation group was 74.1% bacterial clearance rate was significantly higher than 46.0%, the difference was significant (P <0.05). Conclusion That has significant effect of pulmonary infection of the patients with cardiac failure treated by ceftazidime united levofloxacin, and that is worth for promotion in the clinical application.
[Key words] Ceftazidime; Levofloxacin; Cardiac failure; Pulmonary infection
心力衰竭指心脏收缩功能和舒张功能发生障碍,不能够很好的将静脉血排除心脏外,造成静脉血液淤积,引起心脏循环障碍,临床表现为肺部淤血、呼吸困难等症状[1]。研究表明[2-3],所有的心血管疾病最终会导致心力衰竭、心肌梗死、心肌病等心脏疾病的发生,且均以左心室衰竭开始,主要表现为肺循环淤血,容易导致肺部感染,加重心力衰竭,威胁患者的生命。该研究方便选取2014年6月—2015年11月该院收治的60例心力衰竭患者采用头孢他啶联合左氧氟沙星治疗,分析其治疗疗效,现报道如下。
1 资料与方法
1.1 一般资料
方便选取该院收治的符合心力衰竭肺部感染诊断患者60例,将所有患者随机分为两组,观察组30例,男14例,女16例,年龄30-68岁,平均年龄(58.2±2.7)岁。对照组30例,男16例,女14例,年龄35~75岁,平均年龄(62.3±2.2)岁。两组患者的年龄、性别等一般资料比较,差异无统计学意义(P>0.05),具有可比性,且所有患者通过伦理委员会的批准。
1.2 方法
患者入院时均要求卧床休息,严密监测患者的生命体征,并严格控制患者食用钠盐。给予对照组患者静脉注射左氧氟沙星(扬子江药业集团有限公司,国药准字H20143200,生产批号20140304),将0.4 g左氧氟沙星混合250 mL葡萄糖注射液中,1次/d,7~14 d为1个疗程;观察组在对照组基础上加用头孢他啶(国药准字H20033816)治疗,将2.0 g头孢他啶混合150 mL生理盐水中静脉滴注,2次/d,7~14 d为1个疗程。
1.3 观察指标
对比分析两组患者治疗疗效及治疗后细菌清除率。
1.4 判定标准
疗效判定[4]:①显效:肺部感染全部消失,心脏功能恢复正常;②有效:肺部感染基本消失,心脏功能得到缓解,患者临床症状较治疗前有所改善;③无效:肺部感染依旧存在,患者病情并未缓解。
1.5 统计方法
通过SPSS 20.0统计学软件对数据进行分析,用[n(%)]表示计数资料,使用χ2检验,P<0.05时差异有统计学意义。 (吐尔逊那依·斯马依)