血栓前体蛋白及D—二聚体检测在脑梗塞诊断及治疗中的临床意义(1)
[摘要] 目的 探析血栓前体蛋白护D-二聚体检测在脑梗塞诊断及治疗中的临床意义。方法 方便选取2015年1月—2016年1月期间在该院就诊的54例急性脑梗死患者(观察组)，对所有患者资料进行回顾性分析，治疗后，对血浆D-二聚体和血栓前提蛋白的含量予以测定，同期再选取36例为对照组，两组进行比较。 结果 该研究结果显示该组患者发病后6 h内D-Dimer为(0.52±0.21)mg/L，TpP为(23.23±9.96)mg/L；6～12 h分别为(0.60±0.35)mg/L，TpP为(21.52±9.83)mg/L；12～24 h分别为(1.45±0.89)mg/L，TpP为(15.41±8.28)mg/L；；对照组患者D-Dimer为(0.24±0.18)mg/L，TpP为(2.16±1.26)mg/L；在发病后12 h内，D-二聚体存在明显升高现象，其浓度会随着病情时间的延长呈上升趋势，并且高浓度状况的维持时间也相对较长。在发病后6 h内，虽然TpP水平会发生明显上升状态，但经临床治疗后会急剧降低。 结论 D-二聚体和血栓前体蛋白不但是早期诊断急性脑梗死病症的可靠指标，同时还能对疾病的发展予以检测，有效评价其治疗效果。
[关键词] 血栓前体蛋白；D-二聚体；脑梗塞
[中图分类号] R446.6 [文献标识码] A [文章编号] 1674-0742(2016)10(a)-0037-03
Clinical Significance of the Detection of Thrombus Precursor Protein and D- Two in the Diagnosis and Treatment of Cerebral Infarction
QIN Xiu-jie， JIANG Li-hua
Jinan Second People's Hospital Clinical Laboratory， Jinan， Shandong Province，250001 China
[Abstract] Objective To study the clinical significance of the detection of D- two in the diagnosis and treatment of cerebral infarction with thrombus precursor protein. Methods Convenient selection please add exact packet basis， group name， cases of each group number， and in the English abstract to be revised： select January 2015 to January 2016 period in our hospital for treatment of 54 cases of acute cerebral infarction patients(observation group). Of all the patients were retrospectively analyzed， after the treatment， the plasma D-dimer and thrombus precursor protein content to be determined. At the same time， and then select the 36 cases as the control group. The two groups were compared. Results The results show that the group of patients (0.52 ±0.21) mg/L， and the TPP (23.23 ± 996) mg/L in the 6～12 hours respectively (0.60 ± 0.35) mg/L， and the TPP (21.52± 983) mg/L respectively (1.45 ± 0.89) mg/L， and the TPP (15.41± 8.28) mg/L， and the control group patients(0.24 ± 0.18) mg/L， and the TPP (2.16 ± 1.26) mg/L in the pathogenesis after 12 hours， D - dimer has significantly increased， the concentration with time to disease to extend a rising trend， and high concentrations of maintenance time is relatively long. Within 6 hours after the onset of the disease， although the level of TpP will be significantly increased， but the clinical treatment will be significantly reduced. Conclusion D- dimer and thrombus precursor protein in the early diagnosis of acute cerebral infarction is not only a reliable indicator of illness， while the development of the disease to be detected， effective evaluation of its therapeutic effect. (秦秀杰 姜莉华)
[关键词] 血栓前体蛋白；D-二聚体；脑梗塞
[中图分类号] R446.6 [文献标识码] A [文章编号] 1674-0742(2016)10(a)-0037-03
Clinical Significance of the Detection of Thrombus Precursor Protein and D- Two in the Diagnosis and Treatment of Cerebral Infarction
QIN Xiu-jie， JIANG Li-hua
Jinan Second People's Hospital Clinical Laboratory， Jinan， Shandong Province，250001 China
[Abstract] Objective To study the clinical significance of the detection of D- two in the diagnosis and treatment of cerebral infarction with thrombus precursor protein. Methods Convenient selection please add exact packet basis， group name， cases of each group number， and in the English abstract to be revised： select January 2015 to January 2016 period in our hospital for treatment of 54 cases of acute cerebral infarction patients(observation group). Of all the patients were retrospectively analyzed， after the treatment， the plasma D-dimer and thrombus precursor protein content to be determined. At the same time， and then select the 36 cases as the control group. The two groups were compared. Results The results show that the group of patients (0.52 ±0.21) mg/L， and the TPP (23.23 ± 996) mg/L in the 6～12 hours respectively (0.60 ± 0.35) mg/L， and the TPP (21.52± 983) mg/L respectively (1.45 ± 0.89) mg/L， and the TPP (15.41± 8.28) mg/L， and the control group patients(0.24 ± 0.18) mg/L， and the TPP (2.16 ± 1.26) mg/L in the pathogenesis after 12 hours， D - dimer has significantly increased， the concentration with time to disease to extend a rising trend， and high concentrations of maintenance time is relatively long. Within 6 hours after the onset of the disease， although the level of TpP will be significantly increased， but the clinical treatment will be significantly reduced. Conclusion D- dimer and thrombus precursor protein in the early diagnosis of acute cerebral infarction is not only a reliable indicator of illness， while the development of the disease to be detected， effective evaluation of its therapeutic effect. (秦秀杰 姜莉华)