生理性盐水喷雾洗鼻液治疗轻度间歇性变态反应性鼻炎患儿临床效果分析(1)
[摘要] 目的 探討生理性盐水喷雾洗鼻液治疗轻度间歇性变态反应性鼻炎患儿在临床中的应用效果。方法 对从2015年4月—2016年4月在该院就诊的74例轻度间歇性AR小儿患者根据随机数字表法随机的分为对照组和实验组，每组有37例患儿，对照组患儿给予药物氯雷他定治疗，实验组在对照组氯雷他定治疗的基础上，联合使用药物生理性盐水喷雾洗鼻液；对比分析两组患儿AR症状、AR体征评分、纤毛传输速率和临床效果。结果 ①在治疗后，两组患儿在AR症状和体征评分上均有所改善，但是实验组患儿的AR症状和体征评分减少率显著优于对照组患儿(P<0.05)。②治疗后，对照组纤毛传输速率为(5.66±1.09)mm/min，实验组为(6.51±1.07)mm/min，与治疗前相比差异有统计学意义(P<0.05)；但实验组患儿纤毛传输速率显著的高于对照组患儿(P<0.05)。③在对照组中，有7例患儿无效，有30例患儿有效和显效，总有效率为81.08%；实验组中，有1例患儿无效，36例患儿有效和显效，总有效率为97.30%；差异有统计学意义(P<0.05)。结论 生理性盐水喷雾洗鼻液联合氯雷他定治疗轻度间歇性AR患儿，患儿AR症状、体征评分改善状况较优，能够显著的增强纤毛传输速率和临床有效率，在临床中具有推广和应用的价值。
[关键词] 轻度间歇性变态反应性鼻炎；生理性盐水喷雾洗鼻液；氯雷他定
[中图分类号] R765.21 [文献标识码] A [文章编号] 1674-0742(2017)02(a)-0125-03
[Abstract] Objective To discuss the clinical application effect of physiological saline spray nasal wash in treatment of children with mild intermittent anaphylactic rhinitis. Methods 74 cases of children with mild intermittent anaphylactic rhinitis treated in our hospital from April 2015 to April 2016 were selected and randomly divided into two groups with 37 cases in each， the control group were treated with clarityne， while the experimental group were treated with physiological saline spray Nasal Wash on the basis of the control group， and the AR symptom， AR body sign score， cilia transmission speed and clinical effect of the two groups were compared and analyzed. Results After treatment， the AR symptoms and body sign score in the two groups were improved but the AR symptom and body sign score decrease rate in the experimental group was obviously better than that in the control group(P<0.05). After treatment， the difference in the cilia transmission speed in the control group before and after treatment had statistical significance[5.66±1.09)mm/min vs(6.51±1.07)mm/min]， and the cilia transmission speed in the experimental group was obviously higher than that in the control group(P<0.05). In the control group， 7 cases were ineffective， 30 cases were effective and markedly effective， and the effective rate was 81.08%； in the experimental group， 1 case was ineffective， 36 cases were effective and markedly effective， and the effective rate was 97.30%， and the difference had statistical significance(P<0.05). Conclusion The AR symptom and body sign score improvement condition of physiological saline spray nasal wash in treatment of children with mild intermittent anaphylactic rhinitis is better， which can obviously improve the cilia transmission rate and clinical effective rate， and it is worth promotion and application in clinic., 百拇医药(姜涛)
[关键词] 轻度间歇性变态反应性鼻炎；生理性盐水喷雾洗鼻液；氯雷他定
[中图分类号] R765.21 [文献标识码] A [文章编号] 1674-0742(2017)02(a)-0125-03
[Abstract] Objective To discuss the clinical application effect of physiological saline spray nasal wash in treatment of children with mild intermittent anaphylactic rhinitis. Methods 74 cases of children with mild intermittent anaphylactic rhinitis treated in our hospital from April 2015 to April 2016 were selected and randomly divided into two groups with 37 cases in each， the control group were treated with clarityne， while the experimental group were treated with physiological saline spray Nasal Wash on the basis of the control group， and the AR symptom， AR body sign score， cilia transmission speed and clinical effect of the two groups were compared and analyzed. Results After treatment， the AR symptoms and body sign score in the two groups were improved but the AR symptom and body sign score decrease rate in the experimental group was obviously better than that in the control group(P<0.05). After treatment， the difference in the cilia transmission speed in the control group before and after treatment had statistical significance[5.66±1.09)mm/min vs(6.51±1.07)mm/min]， and the cilia transmission speed in the experimental group was obviously higher than that in the control group(P<0.05). In the control group， 7 cases were ineffective， 30 cases were effective and markedly effective， and the effective rate was 81.08%； in the experimental group， 1 case was ineffective， 36 cases were effective and markedly effective， and the effective rate was 97.30%， and the difference had statistical significance(P<0.05). Conclusion The AR symptom and body sign score improvement condition of physiological saline spray nasal wash in treatment of children with mild intermittent anaphylactic rhinitis is better， which can obviously improve the cilia transmission rate and clinical effective rate， and it is worth promotion and application in clinic., 百拇医药(姜涛)