静脉注射山莨菪碱缩短产程的临床分析(1)
[摘要] 目的 观察探究静脉注射山莨菪碱用于缩短产程的临床效果。方法 方便选取该院产科2015年1—12月收治的100名初产妇作为研究对象，按照随机抽签法分为观察組(50名，待宫口扩张3 cm以后给予盐酸消旋山莨当碱10 mg静脉滴注)和对照组(50名，给予缩宫素)，对比两组产妇产程时间、分娩方式以及母婴并发症等情况。结果 观察组产妇第一产程(74.1±24.2)min、第二产程(55.2±28.1)min以及总产程时间(664.1±268.2)min均明显短于对照组(P<0.05)。观察组产妇自然分娩率(86.0%)显著高于对照组(60.0%)，且观察组新生儿窒息率(0.0%)、产后大出血率(2.0%)显著低于对照组，组间对比差异有统计学意义(P<0.05)。结论 产科分娩中合理应用山莨菪碱可有效缩短产程，降低剖宫产率，减少母婴并发症的发生，可在临床上广泛推广应用。
[关键词] 山莨菪碱；产程；临床分析
[中图分类号] R453 [文献标识码] A [文章编号] 1674-0742(2017)08(a)-0121-03
[Abstracts] Objective This paper tries to observe the clinical effect of intravenous injection of anisodamine to shorten the labor course. Methods 100 cases of early pregnant women from January 2015 to December 2015 in this hospital were convenient selected and randomly divided into the observation group and the control group with 50 cases in each group. The observation group received racemic anisodamine alkali 10mg intravenous infusion when the cervical dilatation was of 3cm) and the control group was given oxytocin， the labor course， mode of delivery and maternal complications of the two groups were compared. Results The first stage of labor was (74.1±24.2)min， the second stage of labor was (55.2±28.1)min and the total labor time was(664.1±268.2)min of the observation group， significantly shorter than those in the control group(P<0.05). The maternal natural childbirth rate in the observation group was 86.0%， significantly higher than the control group of 60.0%， the rate of neonatal asphyxia， postpartum hemorrhage rate was 0.0% and 2.0%， significantly lower than the control group， there was significant difference between the two groups (P<0.05). Conclusion Reasonable application of anisodamine in obstetric delivery can effectively shorten the labor， reduce cesarean section rate and the incidence of maternal and infant complications， and it is worth clinical application.
[Key words] Anisodamine； Labor； Clinical analysis
产程进展缓慢是目前临床分娩过程中较为常见的问题，这和宫颈质地硬、宫缩乏力、过于紧张害怕等多方面因素有关[1]。若产妇有效宫缩后，宫颈扩张效果并不是很理想的话，不仅会出现宫颈水肿、裂伤等现象，也会使产程延长，增加剖宫产风险。而且，可能由于阴道操作过多容易导致感染，如何有效控制产妇产程进展，对于母婴分娩结局有直接的联系[2]。山莨菪碱是一种M 型胆碱受体拮抗剂，在临床产科得到广泛应用，特别适用于产妇活跃期宫颈扩张、早孕流产术以及促进产程进展等[3]。为观察分析产科分娩应用山莨菪碱缩短产程的效果，该文回顾性分析了该院2015年1—12月收治的100名初产妇分娩中静脉注射山莨菪碱的效果，现报道如下。
1 资料与方法
1.1 一般资料
方便选取该院产科收治的100名初产妇作为研究对象，所有产妇均为单胎头位足月妊娠，并没有合并胎位异常、前置胎盘等症状。现将100名初产妇按照随机抽签法随机分为观察组(50名)和对照组(50名)，观察组年龄20～30岁，平均年龄(24.9±2.8)岁；孕周37～41周，平均孕周(39.8±1.5)周。对照组年龄20～30岁，平均年龄(25.2±2.6)岁；孕周37～42周，平均孕周(39.4±1.7)周。两组产妇上述基本资料经过分析表明差异无统计学意义(P>0.05)。, 百拇医药(牟俊华)
[关键词] 山莨菪碱；产程；临床分析
[中图分类号] R453 [文献标识码] A [文章编号] 1674-0742(2017)08(a)-0121-03
[Abstracts] Objective This paper tries to observe the clinical effect of intravenous injection of anisodamine to shorten the labor course. Methods 100 cases of early pregnant women from January 2015 to December 2015 in this hospital were convenient selected and randomly divided into the observation group and the control group with 50 cases in each group. The observation group received racemic anisodamine alkali 10mg intravenous infusion when the cervical dilatation was of 3cm) and the control group was given oxytocin， the labor course， mode of delivery and maternal complications of the two groups were compared. Results The first stage of labor was (74.1±24.2)min， the second stage of labor was (55.2±28.1)min and the total labor time was(664.1±268.2)min of the observation group， significantly shorter than those in the control group(P<0.05). The maternal natural childbirth rate in the observation group was 86.0%， significantly higher than the control group of 60.0%， the rate of neonatal asphyxia， postpartum hemorrhage rate was 0.0% and 2.0%， significantly lower than the control group， there was significant difference between the two groups (P<0.05). Conclusion Reasonable application of anisodamine in obstetric delivery can effectively shorten the labor， reduce cesarean section rate and the incidence of maternal and infant complications， and it is worth clinical application.
[Key words] Anisodamine； Labor； Clinical analysis
产程进展缓慢是目前临床分娩过程中较为常见的问题，这和宫颈质地硬、宫缩乏力、过于紧张害怕等多方面因素有关[1]。若产妇有效宫缩后，宫颈扩张效果并不是很理想的话，不仅会出现宫颈水肿、裂伤等现象，也会使产程延长，增加剖宫产风险。而且，可能由于阴道操作过多容易导致感染，如何有效控制产妇产程进展，对于母婴分娩结局有直接的联系[2]。山莨菪碱是一种M 型胆碱受体拮抗剂，在临床产科得到广泛应用，特别适用于产妇活跃期宫颈扩张、早孕流产术以及促进产程进展等[3]。为观察分析产科分娩应用山莨菪碱缩短产程的效果，该文回顾性分析了该院2015年1—12月收治的100名初产妇分娩中静脉注射山莨菪碱的效果，现报道如下。
1 资料与方法
1.1 一般资料
方便选取该院产科收治的100名初产妇作为研究对象，所有产妇均为单胎头位足月妊娠，并没有合并胎位异常、前置胎盘等症状。现将100名初产妇按照随机抽签法随机分为观察组(50名)和对照组(50名)，观察组年龄20～30岁，平均年龄(24.9±2.8)岁；孕周37～41周，平均孕周(39.8±1.5)周。对照组年龄20～30岁，平均年龄(25.2±2.6)岁；孕周37～42周，平均孕周(39.4±1.7)周。两组产妇上述基本资料经过分析表明差异无统计学意义(P>0.05)。, 百拇医药(牟俊华)