[摘要] 目的 探讨妊娠肝内胆汁淤积症的围生期结局。方法 该次观察性研究方便选取2015年10月—2016年12月该院收治的57例妊娠期肝内胆汁淤积症病例，观察分娩前后的各项指标，研究孕产妇和围产儿结局。结果 超过87%的患者在30周后出现泛发性瘙痒，手掌和脚掌是受影响最严重的部位。血清转氨酶水平往往较高。所有纳入病例应用熊去氧胆酸后，瘙痒症得到部分或完全的缓解，血清转氨酶和胆红素水平降低。其中42.11%进行了剖宫产手术。结论 围产期结局不良患者血清转氨酶水平较高，对妊娠肝内胆汁淤积症进行有效干预有助于改善围产儿预后。

    [关键词] 妊娠肝内胆汁淤积症；围产期结局；血清转氨酶

    [中图分类号] R71 [文献标识码] A [文章编号] 1674-0742(2017)09(b)-0065-03

    [Abstract] Objective This paper tries to investigate the perinatal outcome of intrahepatic cholestasis of pregnancy. Methods Convenient selection The observational study included 57 cases from October 2015 to December 2016 of intrahepatic cholestasis of pregnancy. The indexes before and after childbirth were observed. The outcomes of maternal and perinatal were studied. Results More than 87% of patients had generalized itching after 30 weeks ......