青中年脑梗死TOAST分型及危险因素分析(1)
[摘要] 目的 探讨青中年脑梗死的相关危险因素及根据TOAST分型进行病因分析。方法 方便收集该院2016年8月—2017年8月的青中年脑梗死患者102例，并选取其他非脑梗死同年龄患者为对照组，发病危险因素采用Logistic回归分析，并进行TOAST分型，分析青中年脑梗死病因。结果 根据TOAST分型，40岁以下患者为其他疾病所致脑梗死，40岁以上患者动脉粥样硬化为主，大动脉粥样硬化患者多于小动脉闭塞患者。经危险因素分析，吸烟、糖尿病及高血压的B值均远远大于0，与对照组相比差异有统计学意义(P<0.05)。 结论 吸烟、糖尿病及高血压为青中年脑梗死的危险因素；根据TOAST分型，青中年脑梗死病因复杂、多样，需注意鉴别。
[关键词] 青中年脑梗死；TOAST分型；危险因素
[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742(2018)03(c)-0087-03
Analysis of TOAST Typing and Risk Factors of Cerebral Infarction of the Young and Middle-age People
ZHU Jie1， YANG Li-ying2
1.First Department of Neurology， Honghe First People’s Hospital， Mengzi， Yunnan Province， 661199 China；2.Department of Pathology， Honghe First People’s Hospital， Mengzi， Yunnan Province， 661199 China
[Abstract] Objective To study the analysis of TOAST typing and risk factors of cerebral infarction of the young and middle-age people. Methods 102 cases of young and middle-age people with cerebral infarction in our hospital from August 2016 to August 2017 were convenient selected， and the patients under the same age with non- cerebral infarction were selected as the control group， and the onset risk factors were for Logistic regression analysis， and TOAST typing， and the causes were analyzed. Results The patients under 40 were caused by other diseases according to the TOAST typing， and the patients aged more than 40 were mainly with atherosclerosis， and the patients with large atherosclerosis were less than the small atherosclerosis， and the risk factors analysis showed that the B values of smoking， diabetes and hypertension were much higher than 0， and the differences between the two groups were statistically significant(P<0.05). Conclusion The smoking， diabetes and hypertension are the risk factors of cerebral infarction of the young and middle-age people， and the causes are complex and multiple according to the TOAST typing， which needs the identification.
[Key words] Cerebral infarction of the young and middle-age people； TOAST typing； Risk factor
近幾年，脑梗死的发病呈现出年轻化特点，具有较高的致残率及致死率，了解脑梗死的发病原因及危险因素对于该病的防治至关重要。该文通过研究2016年8月—2017年8月收治的102例青中年脑梗死患者，经TOAST分型对其脑梗死病因及危险因素进行分析，以期对青中年高危人群做到早期危险因素干预，对预防或延迟该病的发生提供临床理论依据，现报道如下。
1 资料与方法
1.1 一般资料
方便收集该院收治的青中年患者102例，并选取其他非脑梗死同年龄患者为对照组，入组年龄<60岁，其中<45岁为青年人，45～60岁为中年人。患者组中男72例，女30例，平均年龄49.95岁，其中青年患者20例，男17例，女3例；中年患者82例，男55例，女27例。所有患者均符合中国急性缺血性脑卒中诊治指南2014诊断标准[1]，并经头颅CT、磁共振(平扫+DWI+MRA)检查证实。
1.2 检测指标
统计入组患者个人史、既往史及家族史，行血常规、尿常规及大便常规、凝血功能、肝、肾功、同型半胱氨酸、超敏C反应蛋白、传染性指标、甲功、抗核抗体谱等实验室检查，其他检查包括常规心电图、颈部血管超声、心脏超声、腹部超声、胸片，部分患者完善头颈部CTA检查及必要时动态心电图检查。, http://www.100md.com(朱杰 杨丽英)
[关键词] 青中年脑梗死；TOAST分型；危险因素
[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742(2018)03(c)-0087-03
Analysis of TOAST Typing and Risk Factors of Cerebral Infarction of the Young and Middle-age People
ZHU Jie1， YANG Li-ying2
1.First Department of Neurology， Honghe First People’s Hospital， Mengzi， Yunnan Province， 661199 China；2.Department of Pathology， Honghe First People’s Hospital， Mengzi， Yunnan Province， 661199 China
[Abstract] Objective To study the analysis of TOAST typing and risk factors of cerebral infarction of the young and middle-age people. Methods 102 cases of young and middle-age people with cerebral infarction in our hospital from August 2016 to August 2017 were convenient selected， and the patients under the same age with non- cerebral infarction were selected as the control group， and the onset risk factors were for Logistic regression analysis， and TOAST typing， and the causes were analyzed. Results The patients under 40 were caused by other diseases according to the TOAST typing， and the patients aged more than 40 were mainly with atherosclerosis， and the patients with large atherosclerosis were less than the small atherosclerosis， and the risk factors analysis showed that the B values of smoking， diabetes and hypertension were much higher than 0， and the differences between the two groups were statistically significant(P<0.05). Conclusion The smoking， diabetes and hypertension are the risk factors of cerebral infarction of the young and middle-age people， and the causes are complex and multiple according to the TOAST typing， which needs the identification.
[Key words] Cerebral infarction of the young and middle-age people； TOAST typing； Risk factor
近幾年，脑梗死的发病呈现出年轻化特点，具有较高的致残率及致死率，了解脑梗死的发病原因及危险因素对于该病的防治至关重要。该文通过研究2016年8月—2017年8月收治的102例青中年脑梗死患者，经TOAST分型对其脑梗死病因及危险因素进行分析，以期对青中年高危人群做到早期危险因素干预，对预防或延迟该病的发生提供临床理论依据，现报道如下。
1 资料与方法
1.1 一般资料
方便收集该院收治的青中年患者102例，并选取其他非脑梗死同年龄患者为对照组，入组年龄<60岁，其中<45岁为青年人，45～60岁为中年人。患者组中男72例，女30例，平均年龄49.95岁，其中青年患者20例，男17例，女3例；中年患者82例，男55例，女27例。所有患者均符合中国急性缺血性脑卒中诊治指南2014诊断标准[1]，并经头颅CT、磁共振(平扫+DWI+MRA)检查证实。
1.2 检测指标
统计入组患者个人史、既往史及家族史，行血常规、尿常规及大便常规、凝血功能、肝、肾功、同型半胱氨酸、超敏C反应蛋白、传染性指标、甲功、抗核抗体谱等实验室检查，其他检查包括常规心电图、颈部血管超声、心脏超声、腹部超声、胸片，部分患者完善头颈部CTA检查及必要时动态心电图检查。, http://www.100md.com(朱杰 杨丽英)
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