支气管镜下冷冻联合氩等离子电凝治疗中央气道肺癌(1)
[摘要] 目的 分析在中央气道肺癌患者的临床治疗当中，患者接受支气管镜下冷冻治疗与氩等离子电凝治疗的具体效果。方法 方便选择该院在2017年1—12月收治的28例中央气道肺癌患者为主要对象，根据其治疗方案差异均分成化疗组与联合组，每组14例患者。化疗组患者接受临床常规化疗治疗，联合组患者则同时接受支气管镜下冷冻与氩等离子电凝治疗，对比两组患者的临床治疗效果、不良反应发生情况以及患者治疗前后的呼吸困难情况。结果 联合组患者的临床治疗有效率达到92.9%，高于化疗组患者50.0%有效率，联合组不良反应仅有1例，明显少于化疗组，且联合组患者治疗之后的呼吸困难症状得到更好缓解，相关数据比较差异有统计学意义(P<0.05)。结论 在中央气道肺癌的治疗中，患者同时接受支气管镜下冷冻与氩等离子电凝治疗的效果较好，两种方案联用值得在临床当中推广。
[关键词] 中央气道肺癌；支气管镜；氩等离子；电凝；冷冻；联合
[中图分类号] R730 [文献标识码] A [文章编号] 1674-0742(2018)05(c)-0047-03
[Abstract] Objective This paper tries to analyze the effect of bronchoscopic cryotherapy and argon plasma coagulation therapy in the clinical treatment of patients with central airway lung cancer. Methods 28 central airway cancer patients treated in this hospital from January to December 2017 were convenient selected as the main subjects. According to the differences in treatment options， they were divided into chemotherapy and combination groups， with 14 patients in each group. Patients in the chemotherapy group received conventional chemotherapy. Patients in the combined group underwent simultaneous bronchoscopic cryosurgery and argon plasma coagulation. The clinical efficacy， adverse reactions， and dyspnea before and after treatment were compared between the two groups. Results The effective rate of clinical treatment in the combined group was 92.9%， higher than that in the chemotherapy group of 50.0%， and only one adverse event in the combination group was significantly lower than that in the chemotherapy group， and the dyspnea symptoms of the combined group were better after treatment. Remission， relevant data were significantly different after comparison(P<0.05). Conclusion In the treatment of central airway lung cancer， patients have good results of simultaneous bronchoscopic cryosurgery and argon plasma coagulation. The combination of the two regimens is worthy of promotion in clinical practice.
[Key words] Central airway lung cancer； Bronchoscopy； Argon plasma； Electrocoagulation； Cryotherapy； Union
肺癌在臨床当中也被称作为肺部恶性肿瘤，是目前我国癌症患者当中最为常见的病变类型，在肺癌患者当中，中央气道肺癌患者并不鲜见[1]。中央气道肺癌患者在发病之后，会出现明显的中央气道阻塞情况，患者的主要症状表现为咳血、咳嗽、呼吸困难等[2]。中央气道肺癌主要是指患者段支气管以上至主气管部位的肺癌，这类患者可以占到肺癌患者总数的3/4左右[3]。根据世界卫生组织的相关数据统计，世界范围内每年约有超过130万人死于肺癌，而其中超过八成的患者在被确诊的时候就失去了手术治疗的机会[4]。中央气道肺癌患者的肿瘤会造成其气道严重阻塞，患者呼吸会十分困难，很多患者会因此而出现呼吸衰竭直至死亡[5]。中央气道肺癌患者的病理类型绝大多数为鳞癌，腺癌患者相对较少，还有很多患者为小细胞癌[6]。中央气道肺癌患者的肺部功能会出现严重受限的情况，患者气短情况十分严重，无论是健康还是生活质量都会受到严重影响[7]。该院在2017年1—12月28例患者的治疗中将两种治疗方案相结合，现报道如下。
1 资料与方法
1.1 一般资料, 百拇医药(时海洋 亓志华)
[关键词] 中央气道肺癌；支气管镜；氩等离子；电凝；冷冻；联合
[中图分类号] R730 [文献标识码] A [文章编号] 1674-0742(2018)05(c)-0047-03
[Abstract] Objective This paper tries to analyze the effect of bronchoscopic cryotherapy and argon plasma coagulation therapy in the clinical treatment of patients with central airway lung cancer. Methods 28 central airway cancer patients treated in this hospital from January to December 2017 were convenient selected as the main subjects. According to the differences in treatment options， they were divided into chemotherapy and combination groups， with 14 patients in each group. Patients in the chemotherapy group received conventional chemotherapy. Patients in the combined group underwent simultaneous bronchoscopic cryosurgery and argon plasma coagulation. The clinical efficacy， adverse reactions， and dyspnea before and after treatment were compared between the two groups. Results The effective rate of clinical treatment in the combined group was 92.9%， higher than that in the chemotherapy group of 50.0%， and only one adverse event in the combination group was significantly lower than that in the chemotherapy group， and the dyspnea symptoms of the combined group were better after treatment. Remission， relevant data were significantly different after comparison(P<0.05). Conclusion In the treatment of central airway lung cancer， patients have good results of simultaneous bronchoscopic cryosurgery and argon plasma coagulation. The combination of the two regimens is worthy of promotion in clinical practice.
[Key words] Central airway lung cancer； Bronchoscopy； Argon plasma； Electrocoagulation； Cryotherapy； Union
肺癌在臨床当中也被称作为肺部恶性肿瘤，是目前我国癌症患者当中最为常见的病变类型，在肺癌患者当中，中央气道肺癌患者并不鲜见[1]。中央气道肺癌患者在发病之后，会出现明显的中央气道阻塞情况，患者的主要症状表现为咳血、咳嗽、呼吸困难等[2]。中央气道肺癌主要是指患者段支气管以上至主气管部位的肺癌，这类患者可以占到肺癌患者总数的3/4左右[3]。根据世界卫生组织的相关数据统计，世界范围内每年约有超过130万人死于肺癌，而其中超过八成的患者在被确诊的时候就失去了手术治疗的机会[4]。中央气道肺癌患者的肿瘤会造成其气道严重阻塞，患者呼吸会十分困难，很多患者会因此而出现呼吸衰竭直至死亡[5]。中央气道肺癌患者的病理类型绝大多数为鳞癌，腺癌患者相对较少，还有很多患者为小细胞癌[6]。中央气道肺癌患者的肺部功能会出现严重受限的情况，患者气短情况十分严重，无论是健康还是生活质量都会受到严重影响[7]。该院在2017年1—12月28例患者的治疗中将两种治疗方案相结合，现报道如下。
1 资料与方法
1.1 一般资料, 百拇医药(时海洋 亓志华)