健脾通络汤治疗气虚痰瘀型眩晕症的疗效分析(1)
[摘要] 目的 探究健脾通络汤治疗椎-基底动脉供血不足性眩晕的气虚痰瘀型眩晕症的疗效。方法 方便选取该院2016年1月—2017年12月收治的椎-基底动脉供血不足性眩晕中气虚痰瘀型92例患者作为研究对象，根据数字随机法分为西药组和中药组，每组46例。中药组给予健脾通络汤，西药组给予阿司匹林肠溶片和尼莫地平治疗，观察两组患者治疗前后中医症候评分及临床疗效。结果 治疗后，中药组中医症候评分(1.36±0.98)分优于西药组，比较显示差异有统计学意义(t=2.030，P<0.05)；中药组总有效率为91.30%优于西药组78.26%，对比差异有统计学意义(χ2=6.589，P<0.05)。结论 健脾通络汤可有效缓解气虚痰瘀型眩晕患者中医症候，提高临床疗效。
[关键词] 椎-基底动脉供血不足性眩晕；气虚痰瘀型；眩晕症；健脾通络汤
[中图分类号] R255 [文献标识码] A [文章编号] 1674-0742(2018)06(b)-0145-03
Analysis of Curative Effect of Jianpi Tongluo Tang in Treatment of Qi Deficiency and Sputum Stasis Vertigo
LIAN Jun-jian
Department of TCM， Pengpai Memorial Hospital of Haifeng， Shanwei， Guangdong Province， 516400 China
[Abstract] Objective To study the curative effect of jianpi tongluo tang in treatment of Qi deficiency and sputum stasis vertigo due to Vertebrobasilar insufficiency. Methods 92 cases of patients with qi deficiency and sputum stasis vertigo due to vertebrobasilar insufficiency admitted and treated in our hospital from January 2016 to December 2017 were convenient selected and randomly divided into two groups with 46 cases in each， the TCM group were treated with jianpi tongluo tang， while the western medicine group were treated with aspirin enteric-coated tablets and nimodipine， and the TCM syndrome score of the two groups before and after treatment and clinical curative effect were observed. Results After treatment， the TCM syndrome score in the TCM group was (1.36±0.98)points， which were better than those in the western medicine group， and the differences were not statistically significant (t=2.030， P<0.05)， and the total effective rate in the TCM group was better than that in the western medicine group (91.30% vs 78.26%)， and the difference was statistically significant (χ2=6.589， P<0.05). Conclusion Jianpi tongluo tang can effectively relieve the TCM syndrome of patients with qi deficiency and sputum stasis vertigo and improve the clinical curative effect.
[Key words]Vertigo due to vertebrobasilar insufficiency； Qi deficiency and sputum stasis； Vertigo； Jianpi tongluo tang
隨着人口老龄化以及社会、生活环境变化，椎-基底动脉供血不足性眩晕发病率呈逐渐上升趋势。西医对椎-基底动脉供血不足性眩晕的药物治疗虽具有一定疗效，但治疗方案上缺乏个体性和针对性。中医将椎-基底动脉供血不足性眩晕归纳为“眩晕”范畴，可根据患者不同临床表现辨证论治，减少眩晕发生。笔者查阅大量文献资料，结合临床实践，认为痰湿是眩晕的主要病因，认为健脾通络汤是中医治疗椎-基底动脉供血不足性眩晕中气虚痰瘀型的基本方剂[1-2]。现拟定对2016年1月—2017年12月该院收治的椎-基底动脉供血不足性眩晕中气虚痰瘀型患者给予健脾通络汤治疗，现报道如下。
1 资料与方法
1.1 一般资料
方便选取该院收治的椎-基底动脉供血不足性眩晕中气虚痰瘀型92例患者作为研究对象，根据数字随机法分为西药组和中药组，每组46例。中药组男性28例、女性18例，年龄在58～76岁，平均年龄为(68.35±12.06)岁，合并症：高血压16例、高血脂24例、糖尿病16例、冠心病10例；西药组男性29例、女性17例，年龄在55～74岁，平均年龄为(64.92±10.58)岁，合并症：高血压20例、高血脂26例、糖尿病24例、冠心病16例。两组患者从年龄、性别、合并症等临床基础资料对比显示差异无统计学意义(P>0.05)，组间对比存在可比性。92例均符合《中药新药临床研究指导原则》中对眩晕的中医诊断指标，患者自身有旋转或晃动感，或视物有旋转感，或自觉头晕，晕沉或晕胀不适，且所选病例均通过伦理委员会的批准，患者及家属均知情同意。纳入标准：①患者均符合中医“眩晕”诊断指标，经辩证属于“气虚痰瘀”型；②年龄在50～80岁；③患者无意识障碍；④所有患者均签署研究知情同意书。排除标准：①患者伴有严重的心脏疾病和肝肾功能障碍；②患者影像学显示颅脑内出现占位性病变；③患者依从性差。, http://www.100md.com(连俊健)
[关键词] 椎-基底动脉供血不足性眩晕；气虚痰瘀型；眩晕症；健脾通络汤
[中图分类号] R255 [文献标识码] A [文章编号] 1674-0742(2018)06(b)-0145-03
Analysis of Curative Effect of Jianpi Tongluo Tang in Treatment of Qi Deficiency and Sputum Stasis Vertigo
LIAN Jun-jian
Department of TCM， Pengpai Memorial Hospital of Haifeng， Shanwei， Guangdong Province， 516400 China
[Abstract] Objective To study the curative effect of jianpi tongluo tang in treatment of Qi deficiency and sputum stasis vertigo due to Vertebrobasilar insufficiency. Methods 92 cases of patients with qi deficiency and sputum stasis vertigo due to vertebrobasilar insufficiency admitted and treated in our hospital from January 2016 to December 2017 were convenient selected and randomly divided into two groups with 46 cases in each， the TCM group were treated with jianpi tongluo tang， while the western medicine group were treated with aspirin enteric-coated tablets and nimodipine， and the TCM syndrome score of the two groups before and after treatment and clinical curative effect were observed. Results After treatment， the TCM syndrome score in the TCM group was (1.36±0.98)points， which were better than those in the western medicine group， and the differences were not statistically significant (t=2.030， P<0.05)， and the total effective rate in the TCM group was better than that in the western medicine group (91.30% vs 78.26%)， and the difference was statistically significant (χ2=6.589， P<0.05). Conclusion Jianpi tongluo tang can effectively relieve the TCM syndrome of patients with qi deficiency and sputum stasis vertigo and improve the clinical curative effect.
[Key words]Vertigo due to vertebrobasilar insufficiency； Qi deficiency and sputum stasis； Vertigo； Jianpi tongluo tang
隨着人口老龄化以及社会、生活环境变化，椎-基底动脉供血不足性眩晕发病率呈逐渐上升趋势。西医对椎-基底动脉供血不足性眩晕的药物治疗虽具有一定疗效，但治疗方案上缺乏个体性和针对性。中医将椎-基底动脉供血不足性眩晕归纳为“眩晕”范畴，可根据患者不同临床表现辨证论治，减少眩晕发生。笔者查阅大量文献资料，结合临床实践，认为痰湿是眩晕的主要病因，认为健脾通络汤是中医治疗椎-基底动脉供血不足性眩晕中气虚痰瘀型的基本方剂[1-2]。现拟定对2016年1月—2017年12月该院收治的椎-基底动脉供血不足性眩晕中气虚痰瘀型患者给予健脾通络汤治疗，现报道如下。
1 资料与方法
1.1 一般资料
方便选取该院收治的椎-基底动脉供血不足性眩晕中气虚痰瘀型92例患者作为研究对象，根据数字随机法分为西药组和中药组，每组46例。中药组男性28例、女性18例，年龄在58～76岁，平均年龄为(68.35±12.06)岁，合并症：高血压16例、高血脂24例、糖尿病16例、冠心病10例；西药组男性29例、女性17例，年龄在55～74岁，平均年龄为(64.92±10.58)岁，合并症：高血压20例、高血脂26例、糖尿病24例、冠心病16例。两组患者从年龄、性别、合并症等临床基础资料对比显示差异无统计学意义(P>0.05)，组间对比存在可比性。92例均符合《中药新药临床研究指导原则》中对眩晕的中医诊断指标，患者自身有旋转或晃动感，或视物有旋转感，或自觉头晕，晕沉或晕胀不适，且所选病例均通过伦理委员会的批准，患者及家属均知情同意。纳入标准：①患者均符合中医“眩晕”诊断指标，经辩证属于“气虚痰瘀”型；②年龄在50～80岁；③患者无意识障碍；④所有患者均签署研究知情同意书。排除标准：①患者伴有严重的心脏疾病和肝肾功能障碍；②患者影像学显示颅脑内出现占位性病变；③患者依从性差。, http://www.100md.com(连俊健)