右美托咪定在全身麻醉鼻内镜手术控制性降压中的应用效果(1)
[摘要] 目的 探讨右美托咪定在全身麻醉鼻内镜手术控制性降压中的应用效果。 方法 随机选取该院2015年1月—2017年2月收治的择期行鼻内镜手术患者共62例，对这些患者进行随机分组处理，将这些患者随机分为研究组和对比组两组，每组患者31例。研究组患者在麻醉前20 min，进行右美托咪定静脉泵入的方式对患者进行必要的降压处理，对比组患者在对进行生理盐水输注的方式对患者血压加以有效降低，对两组患者在实施手术之前以及手术过程中患者的血压和心率变化情况进行必要观察，并且加以有效对比分析。 结果 研究组患者在进行右美托咪定药物控制性降压处理之后，患者在鼻内镜手术过程中收缩压和舒张压及心率的最大值分别为(112.4±9.6)mmHg、(70.4±10.3)mmHg、(79.1±12.1)次/min与最小值的数值分別为(92.4±7.4)mmHg、(60.6±5.5)mmHg、(62.6±8.1)次/min，和对比组比较，差异有统计学意义(t=5.714、6.012、5.932，P<0.05；t=7.012、6.354、7.125，P<0.05)。 结论 右美托咪定在全身麻醉鼻内镜手术控制性降压的应用过程中，其降压效果是相对显著的，并且能够有效对患者手术过程中多形成为的血流动力学加以稳定，这一方式具有安全可靠的特点，并且值得临床推广。
[关键词] 右美托咪定；全身麻醉；鼻内镜手术；控制性降压；应用效果
[中图分类号] R765.9 [文献标识码] A [文章编号] 1674-0742(2018)06(c)-0107-03
[Abstract] Objective This paper tries to investigate the effect of dexmedetomidine on controlled hypotension in nasal endoscopic surgery for general anesthesia. Methods A total of 62 patients undergoing elective endoscopic surgery who were admitted to the hospital from January 2015 to February 2017 were randomly selected and randomized into groups. These patients were randomly divided into two groups， the study group and the comparison group. 31 cases in each group. Patients in the study group were treated with dexmedetomidine intravenously for 20 minutes before anesthesia to perform necessary blood pressure decompression. Patients in the comparison group were given effective pressure reduction for the patients who received saline infusion. The patient's blood pressure and heart rate changes were observed before and during the surgery， and the patients were observed and compared effectively. Results After dexmedetomidine drug-controlled antihypertensive treatment was performed in patients in the study group， the maximum values of systolic blood pressure， diastolic blood pressure， and heart rate during endoscopic surgery were (112.4±9.6)mmHg and (70.4±10.3)mmHg， respectively(79.1±12.1) times/min， and minimum were (92.4±7.4)mmHg， (60.6±5.5)mmHg， (62.6±8.1)times/min， and the difference between the control group was statistically significant(t=5.714， 6.012， 5.932， P<0.05； t=7.012， 6.354， 7.125， P<0.05). Conclusion Dexmedetomidine has a significant antihypertensive effect during general anesthesia for controlled decompression of endoscopic surgery， and it can effectively stabilize the hemodynamics formed during surgery， which is safe and reliable， and worthy of clinical promotion.
[Key words] Dexmedetomidine； General anesthesia； Endoscopic surgery； Controlled decompression； Applied effect, 百拇医药(单立刚 彭建良 张成深)
[关键词] 右美托咪定；全身麻醉；鼻内镜手术；控制性降压；应用效果
[中图分类号] R765.9 [文献标识码] A [文章编号] 1674-0742(2018)06(c)-0107-03
[Abstract] Objective This paper tries to investigate the effect of dexmedetomidine on controlled hypotension in nasal endoscopic surgery for general anesthesia. Methods A total of 62 patients undergoing elective endoscopic surgery who were admitted to the hospital from January 2015 to February 2017 were randomly selected and randomized into groups. These patients were randomly divided into two groups， the study group and the comparison group. 31 cases in each group. Patients in the study group were treated with dexmedetomidine intravenously for 20 minutes before anesthesia to perform necessary blood pressure decompression. Patients in the comparison group were given effective pressure reduction for the patients who received saline infusion. The patient's blood pressure and heart rate changes were observed before and during the surgery， and the patients were observed and compared effectively. Results After dexmedetomidine drug-controlled antihypertensive treatment was performed in patients in the study group， the maximum values of systolic blood pressure， diastolic blood pressure， and heart rate during endoscopic surgery were (112.4±9.6)mmHg and (70.4±10.3)mmHg， respectively(79.1±12.1) times/min， and minimum were (92.4±7.4)mmHg， (60.6±5.5)mmHg， (62.6±8.1)times/min， and the difference between the control group was statistically significant(t=5.714， 6.012， 5.932， P<0.05； t=7.012， 6.354， 7.125， P<0.05). Conclusion Dexmedetomidine has a significant antihypertensive effect during general anesthesia for controlled decompression of endoscopic surgery， and it can effectively stabilize the hemodynamics formed during surgery， which is safe and reliable， and worthy of clinical promotion.
[Key words] Dexmedetomidine； General anesthesia； Endoscopic surgery； Controlled decompression； Applied effect, 百拇医药(单立刚 彭建良 张成深)