[摘要] 重症急性胰腺炎属于临床上常见的急腹症，具有病情恶劣、并发症较多以及病死率高等特点，已成为威胁人们身心健康的主要疾病。临床症状主要表现为不同程度腹痛、黄疸、高热、消化道出血、呼吸异常、昏迷甚至休克等，严重威胁患者生命安全。若能够全面掌握患者的发病因素以及机制等，及时采取有效干预措施，可有效改善病情，提高患者生活质量，为预后提供保障。因此该文对重症急性胰腺炎进行综述，分析患者的病因以及发病机制。

    [关键词] 发病机制；重症急性胰腺炎；研究进展；病因

    [中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2018)10(c)-0196-03

    [Abstract] Severe acute pancreatitis is a common acute abdomen in clinical practice. It has the characteristics of poor condition， high complications and high mortality. It has become a major disease threatening people's physical and mental health. The clinical symptoms mainly include different degrees of abdominal pain ......