早产儿呼吸窘迫综合征125例临床分析(1)
[摘要] 目的 研究早產儿呼吸窘迫综合征的临床特征、高危因素及治疗情况，提高对早产儿呼吸窘迫综合征的认识。方法 回顾性分析2015年10月—2017年10月该院就诊的呼吸窘迫综合征早产儿患者125例的临床资料；对基础资料、临床特点、治疗方法及并发症情况进行统计学分析。 结果 125例NRDS中， 男性患者数量大于女性患者，且发病比例随胎龄减少、出生体重减轻均有增加趋势，差异有统计学意义(P<0.05)；胎龄<32周的早期早产儿是发生呼吸窘迫综合征的主要因素，占比43.2%；其次为宫内窘迫/窒息，占比28.0%；剖宫产，占比21.6%等。早期早产儿与晚期早产儿组治疗方法采用PS替代治疗、NCPAP治疗、机械通气治疗等方法的差异无统计学意义(P>0.05)。晚期早产儿组的平均住院(14.3±4.2)d，少于早期早产儿组的住院天数(28.8±5.1)d，两者差异有统计学意义(t=16.595，P<0.05)。早期早产儿组发生肺部感染、败血症、支气管肺发育不良和肺出血的比例高于晚期早产儿组，差异有统计学意义(χ2=4.373， 4.106，4.834，3.971，P<0.05)。 结论 早产儿呼吸窘迫综合征的并发症和住院时间与早产儿的胎龄有关，在诊断和治疗时需要综合考虑各方面因素。
[关键词] 早产儿；呼吸窘迫综合征；临床分析
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2019)02(c)-0076-03
[Abstract] Objective To study the clinical characteristics， high risk factors and treatment of respiratory distress syndrome in premature infants， and to improve the understanding of respiratory distress syndrome in premature infants. Methods The clinical data of 125 cases of premature infants with respiratory distress syndrome from October 2015 to October 2017 were retrospectively analyzed. The basic data， clinical features， treatment methods and complications were analyzed statistically. Results Among 125 patients with NRDS， the number of male patients was greater than that of female patients， and the incidence rate decreased with gestational age and birth weight loss. The difference was statistically significant (P<0.05)； the gestational age was less than 32 weeks of early premature infants were the main cause of respiratory distress syndrome， accounting for 43.2%； followed by intrauterine distress/asphyxia， accounting for 28.0%； cesarean section， accounting for 21.6%. There were no significant differences in the treatment of early preterm infants and late preterm infants with PS replacement therapy， NCPAP therapy， mechanical ventilation therapy (P>0.05). The average hospitalization in the late preterm infants group was (14.3±4.2) d， which was less than that in the early preterm infants group (28.8±5.1) d. The difference was statistically significant (t=16.595， P<0.05). The incidence of pulmonary infection， sepsis， bronchopulmonary dysplasia and pulmonary hemorrhage in the early preterm infants group was higher than that in the late preterm infants group (χ2=4.373， 4.106， 4.834， 3.971， P<0.05). Conclusion The complications and hospitalization time of premature infants with respiratory distress syndrome are related to the gestational age of premature infants. All factors need to be considered in diagnosis and treatment., 百拇医药(周建福)
[关键词] 早产儿；呼吸窘迫综合征；临床分析
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2019)02(c)-0076-03
[Abstract] Objective To study the clinical characteristics， high risk factors and treatment of respiratory distress syndrome in premature infants， and to improve the understanding of respiratory distress syndrome in premature infants. Methods The clinical data of 125 cases of premature infants with respiratory distress syndrome from October 2015 to October 2017 were retrospectively analyzed. The basic data， clinical features， treatment methods and complications were analyzed statistically. Results Among 125 patients with NRDS， the number of male patients was greater than that of female patients， and the incidence rate decreased with gestational age and birth weight loss. The difference was statistically significant (P<0.05)； the gestational age was less than 32 weeks of early premature infants were the main cause of respiratory distress syndrome， accounting for 43.2%； followed by intrauterine distress/asphyxia， accounting for 28.0%； cesarean section， accounting for 21.6%. There were no significant differences in the treatment of early preterm infants and late preterm infants with PS replacement therapy， NCPAP therapy， mechanical ventilation therapy (P>0.05). The average hospitalization in the late preterm infants group was (14.3±4.2) d， which was less than that in the early preterm infants group (28.8±5.1) d. The difference was statistically significant (t=16.595， P<0.05). The incidence of pulmonary infection， sepsis， bronchopulmonary dysplasia and pulmonary hemorrhage in the early preterm infants group was higher than that in the late preterm infants group (χ2=4.373， 4.106， 4.834， 3.971， P<0.05). Conclusion The complications and hospitalization time of premature infants with respiratory distress syndrome are related to the gestational age of premature infants. All factors need to be considered in diagnosis and treatment., 百拇医药(周建福)