经尿道膀胱肿瘤切除术用于治疗膀胱癌的效果分析(1)
[摘要] 目的 探讨经尿道膀胱肿瘤切除术治疗膀胱癌的临床疗效与安全性。方法 方便选取2012年1月—2018年6月该院泌尿外科42例膀胱癌患者为研究对象，依据治疗方法不同分为实验组(经尿道膀胱肿瘤切除术，21例)和对照组(膀胱部分切除术，21例)，对比观察两组治疗指标，术后随访，统计并发症及复发率。 结果 两组手术成功率均为100.00%；实验组手术时间(43.1±8.7)min、术中出血量(38.5±6.4)mL、术后住院时间(6.5±1.1)d、并发症发生率9.52%，各项指标均优于对照组，差异有统计学意义(t=5.746、9.857、3.277，χ2=4.732；P<0.05)；术后随访，实验组膀胱癌复发率(4.76%)与对照组(9.52%)，差异无统计学意义(χ2=2.417，P>0.05)。 结论 经尿道膀胱肿瘤切除术治疗膀胱癌效果确切，安全性高，利于患者术后早期恢复，值得临床推广使用。
[关键词] 膀胱癌；经尿道膀胱肿瘤切除术；膀胱部分切除术；疗效；安全性
[中图分类号] R737 [文献标识码] A [文章编号] 1674-0742(2019)03(a)-0099-03
[Abstract] Objective To investigate the clinical efficacy and safety of transurethral resection of bladder tumor in the treatment of bladder cancer. Methods From January 2012 to June 2018， 42 patients with bladder cancer in our hospital were convenient selected and enrolled in the study. According to the different treatment methods， they were divided into experimental group (transurethral resection of bladder tumor， 21 cases) and control group (partial resection of the bladder surgery， 21 cases)， comparative observation of two groups of treatment indicators， postoperative follow-up， statistical complications and recurrence rate. Results The success rate of the two groups was 100.00%. The operation time of the experimental group was (43.1±8.7) min， the intraoperative blood loss (38.5±6.4)mL， the postoperative hospital stay (6.5±1.1)d， and the complication rate was 9.52%. The indexes were superior to the control group， and the difference was statistically significant (t=5.746， 9.857， 3.277， χ2=4.732；P<0.05). The postoperative follow-up rate of bladder cancer in the experimental group (4.76%) and the control group (9.52%). There was no statistical difference between the two groups (χ2=2.417， P>0.05). Conclusion Transurethral resection of bladder tumor is effective and safe in the treatment of bladder cancer， which is beneficial to the early recovery of patients. It is worthy of clinical promotion.
[Key words] Bladder cancer； Transurethral resection of bladder tumor； Partial cystectomy； Efficacy； Safety
膀胱癌是臨床常见恶性肿瘤，数据统计世界范围内发病率在泌尿生殖系恶性肿瘤中第2位，在全身恶性肿瘤中居第9位[1]。我国非膀胱癌高发国家，流行病学显示男性发病率3.8/10万，居全身恶性肿瘤第8位，女性发病率1.4/10万，排在第12位以后[2]。但近年来受多种因素影响，我国膀胱癌发病率有增高趋势，特别是城市地区，应引起重视[3]。手术是现阶段临床治疗膀胱癌的首选方法，可有效提高患者5年生存率[4]，该院近年以经尿道膀胱肿瘤切除术治疗膀胱癌取得理想效果，文章现以2012年1月—2018年6月该院42例患者为例进行分析探讨，报道如下。
1 资料与方法
1.1 一般资料
方便选取该院泌尿外科收治的42例膀胱癌患者为研究对象，依据治疗方法不同分两组。实验组(21例)：男16例，女5例；年龄46～77岁，平均(62.8±9.3)岁；单发肿瘤13例，多发肿瘤8例；肿瘤最大径0.45～3.9 cm，平均(1.4±0.7)cm；临床分期T217例，T34例；病理分级G17例，G211例，G33例。对照组(21例)男17例，女4例；年龄48～76岁，平均(63.1±8.5)岁；单发肿瘤14例，多发肿瘤7例；肿瘤最大径0.50～4.1 cm，平均(1.6±0.9)cm；临床分期T218例，T33例；病理分级G16例，G212例，G33例。两组一般资料差异无统计学意义(P>0.05)，具有可比性。, http://www.100md.com(郝宝金 徐峰 黄以顺 覃建迪)
[关键词] 膀胱癌；经尿道膀胱肿瘤切除术；膀胱部分切除术；疗效；安全性
[中图分类号] R737 [文献标识码] A [文章编号] 1674-0742(2019)03(a)-0099-03
[Abstract] Objective To investigate the clinical efficacy and safety of transurethral resection of bladder tumor in the treatment of bladder cancer. Methods From January 2012 to June 2018， 42 patients with bladder cancer in our hospital were convenient selected and enrolled in the study. According to the different treatment methods， they were divided into experimental group (transurethral resection of bladder tumor， 21 cases) and control group (partial resection of the bladder surgery， 21 cases)， comparative observation of two groups of treatment indicators， postoperative follow-up， statistical complications and recurrence rate. Results The success rate of the two groups was 100.00%. The operation time of the experimental group was (43.1±8.7) min， the intraoperative blood loss (38.5±6.4)mL， the postoperative hospital stay (6.5±1.1)d， and the complication rate was 9.52%. The indexes were superior to the control group， and the difference was statistically significant (t=5.746， 9.857， 3.277， χ2=4.732；P<0.05). The postoperative follow-up rate of bladder cancer in the experimental group (4.76%) and the control group (9.52%). There was no statistical difference between the two groups (χ2=2.417， P>0.05). Conclusion Transurethral resection of bladder tumor is effective and safe in the treatment of bladder cancer， which is beneficial to the early recovery of patients. It is worthy of clinical promotion.
[Key words] Bladder cancer； Transurethral resection of bladder tumor； Partial cystectomy； Efficacy； Safety
膀胱癌是臨床常见恶性肿瘤，数据统计世界范围内发病率在泌尿生殖系恶性肿瘤中第2位，在全身恶性肿瘤中居第9位[1]。我国非膀胱癌高发国家，流行病学显示男性发病率3.8/10万，居全身恶性肿瘤第8位，女性发病率1.4/10万，排在第12位以后[2]。但近年来受多种因素影响，我国膀胱癌发病率有增高趋势，特别是城市地区，应引起重视[3]。手术是现阶段临床治疗膀胱癌的首选方法，可有效提高患者5年生存率[4]，该院近年以经尿道膀胱肿瘤切除术治疗膀胱癌取得理想效果，文章现以2012年1月—2018年6月该院42例患者为例进行分析探讨，报道如下。
1 资料与方法
1.1 一般资料
方便选取该院泌尿外科收治的42例膀胱癌患者为研究对象，依据治疗方法不同分两组。实验组(21例)：男16例，女5例；年龄46～77岁，平均(62.8±9.3)岁；单发肿瘤13例，多发肿瘤8例；肿瘤最大径0.45～3.9 cm，平均(1.4±0.7)cm；临床分期T217例，T34例；病理分级G17例，G211例，G33例。对照组(21例)男17例，女4例；年龄48～76岁，平均(63.1±8.5)岁；单发肿瘤14例，多发肿瘤7例；肿瘤最大径0.50～4.1 cm，平均(1.6±0.9)cm；临床分期T218例，T33例；病理分级G16例，G212例，G33例。两组一般资料差异无统计学意义(P>0.05)，具有可比性。, http://www.100md.com(郝宝金 徐峰 黄以顺 覃建迪)