血脂与高血压脑卒中患者颈动脉狭窄的相关性研究(1)
[摘要] 目的 探究高血壓脑卒中患者血脂水平与颈动脉狭窄程度的相关性。 方法 方便选取2016年1月—2017年12月98例行高血压合并脑卒中患者为研究对象，所有患者行颈部超声检测，根据患者的颈部动脉狭窄程度分为重度狭窄组(n=41)和轻、中度狭窄组(n=57)，比较两组患者血脂水平，采用Spearman 相关性分析法分析高血压脑卒中患者血脂与颈动脉狭窄的相关性。 结果 共98例(58.33%)患者发生颈部动脉狭窄，发生颈动脉狭窄的患者IMT(1.21±0.34)mm和僵硬度(221.39±86.21)]高于未发生颈动脉狭窄患者[(0.53±0.12)mm，(698.15±98.59)]，扩张性(0.93±0.16)低于未发生颈动脉狭窄患者(0.27±0.07)，差异有统计学意义(P<0.05)。相较于轻度狭窄组与中度狭窄组，重度狭窄组的TC(7.10±1.11)、TG(3.79±0.61)mmol/L和HDL-C(0.97±0.21)mmol/L均处于较高水平，数据比较差异有统计学意义(P<0.05)。相关分析显示，患者颈动脉狭窄程度与患者的血脂水平呈正相关(r=0.669，P=0.027)。 结论 高血压脑卒中患者血脂水平与颈动脉狭窄程度呈正相关，血脂水平偏高时患者经动脉狭窄的发生风险将升高。
, 百拇医药
[关键词] 高血压;脑卒中;血脂;颈动脉狭窄程度;相关性
[中图分类号] R743 [文献标识码] A [文章编号] 1674-0742(2019)06(b)-0040-04
[Abstract] Objective To investigate the relationship between serum lipid levels and carotid stenosis in patients with hypertensive stroke. Methods From January 2016 to December 2017， 98 patients with hypertension and stroke were convenient enrolled. All patients underwent cervical ultrasonography and according to the degree of cervical artery stenosis were divided into severe stenosis (n=41) and the mild and moderate stenosis group (n=57). The blood lipid levels of the two groups were compared. Spearman correlation analysis was used to analyze the correlation between serum lipids and carotid stenosis in patients with hypertensive stroke. Results A total of 98 cases(58.33%) patients had cervical stenosis. IMT (1.21±0.34)mm and stiffness (221.39±86.21) were higher in patients with carotid stenosis than in patients without carotid stenosis [(0.53±0.12)mm， 698.15±98.59)]. The dilatation (0.93±0.16) was lower than that of patients without carotid stenosis (0.27±0.07)， and the difference was statistically significant (P<0.05). Compared with the mild stenosis group and the moderate stenosis group， the TC (7.10±1.11)， TG (3.79±0.61)mmol/L and HDL-C (0.97±0.21)mmol/L in the severe stenosis group were at a high level， and the data were statistically different. Academic significance (P<0.05). Correlation analysis showed that the degree of carotid stenosis was positively correlated with the patient's blood lipid level (r=0.669， P=0.027). Conclusion The blood lipid level of patients with hypertensive stroke is positively correlated with the degree of carotid stenosis. When the blood lipid level is high， the risk of arterial stenosis will increase.
[Key words] Hypertension; Stroke; Blood lipids; Carotid stenosis; Correlation, http://www.100md.com(王艳芬 付金涛 戴红波)
, 百拇医药
[关键词] 高血压;脑卒中;血脂;颈动脉狭窄程度;相关性
[中图分类号] R743 [文献标识码] A [文章编号] 1674-0742(2019)06(b)-0040-04
[Abstract] Objective To investigate the relationship between serum lipid levels and carotid stenosis in patients with hypertensive stroke. Methods From January 2016 to December 2017， 98 patients with hypertension and stroke were convenient enrolled. All patients underwent cervical ultrasonography and according to the degree of cervical artery stenosis were divided into severe stenosis (n=41) and the mild and moderate stenosis group (n=57). The blood lipid levels of the two groups were compared. Spearman correlation analysis was used to analyze the correlation between serum lipids and carotid stenosis in patients with hypertensive stroke. Results A total of 98 cases(58.33%) patients had cervical stenosis. IMT (1.21±0.34)mm and stiffness (221.39±86.21) were higher in patients with carotid stenosis than in patients without carotid stenosis [(0.53±0.12)mm， 698.15±98.59)]. The dilatation (0.93±0.16) was lower than that of patients without carotid stenosis (0.27±0.07)， and the difference was statistically significant (P<0.05). Compared with the mild stenosis group and the moderate stenosis group， the TC (7.10±1.11)， TG (3.79±0.61)mmol/L and HDL-C (0.97±0.21)mmol/L in the severe stenosis group were at a high level， and the data were statistically different. Academic significance (P<0.05). Correlation analysis showed that the degree of carotid stenosis was positively correlated with the patient's blood lipid level (r=0.669， P=0.027). Conclusion The blood lipid level of patients with hypertensive stroke is positively correlated with the degree of carotid stenosis. When the blood lipid level is high， the risk of arterial stenosis will increase.
[Key words] Hypertension; Stroke; Blood lipids; Carotid stenosis; Correlation, http://www.100md.com(王艳芬 付金涛 戴红波)