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编号:13419088
子宫动脉介入化疗栓塞术在宫颈癌治疗中临床疗效(1)
http://www.100md.com 2019年7月15日 《中外医疗》 2019年第20期
     [摘要] 目的 觀察并探讨子宫动脉介入化疗栓塞术在宫颈癌治疗中临床疗效。 方法 方便选取2016年11月—2018年11月期间来该院就诊的126例宫颈癌患者,随机按患者就诊顺序分为对照组与实验组,人数相同各63例,对照组与实验组患者分别给予常规静脉化疗、子宫动脉介入化疗栓塞术治疗,对两组患者治疗后不良反应发生情况、淋巴结转移率、肿瘤大小变化情况、临床治疗有效率进行评价与对比。 结果 实验组患者淋巴结转移率、临床治疗有效率与对照组结果比较均显著较优,实验组患者肿瘤缩小>50%的发生率显著高于对照组,差异有统计学意义(P<0.05)。实验组患者治疗后肝肾功能损伤、血细胞异常、恶心呕吐、感染以及出血等不良反应发生率(7.93%)与对照组(34.92%)结果比较均显著较低,差异有统计学意义(P<0.05)。 结论 子宫动脉介入化疗栓塞术在宫颈癌临床治疗中应用具有确切疗效,值得推广应用。

    [关键词] 子宫动脉介入化疗栓塞术;宫颈癌;临床疗效

    [中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2019)07(b)-0013-04
, 百拇医药
    Clinical Efficacy of Uterine Artery Interventional Chemoembolization in the Treatment of Cervical Cancer

    HUANG Cui-ping

    Department of Obstetrics and Gynecology, Laiwu Iron and Steel Hospital, Laiwu, Shandong Province, 271100 China

    [Abstract] Objective To observe and explore the clinical efficacy of uterine artery interventional chemoembolization in the treatment of cervical cancer. Methods A total of conveniently selected 126 patients with cervical cancer who came to our hospital from November 2016 to November 2018 were randomly divided into the control group and the experimental group according to the order of the patients. The number of patients was the same in 63 cases. The control group and the experimental group respectively adopted routine intravenous chemotherapy and uterine artery interventional chemoembolization. The incidence of adverse reactions, lymph node metastasis rate, tumor size change and clinical treatment efficiency were evaluated and compared. Results The lymph node metastasis rate and clinical treatment efficiency of the experimental group were significantly better than those of the control group. The incidence of tumor shrinkage >50% in the experimental group was significantly higher than that of the control group. The difference was statistically significant(P<0.05). The incidence of adverse reactions such as liver and kidney function damage, blood cell abnormalities, nausea and vomiting, infection and hemorrhage in the experimental group (7.93%) was significantly lower than that in the control group (34.92%). The difference was statistically significant(P<0.05). Conclusion Uterine artery interventional chemoembolization has a definite therapeutic effect in the clinical treatment of cervical cancer, and it is worthy of popularization and application.

    [Key words] Uterine artery interventional chemoembolization; Cervical cancer; Clinical efficacy, 百拇医药(黄翠萍)
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