探讨多种血液净化方法联用并结合护理干预在 尿毒症CKD-MBD治疗中的临床效果(1)
[摘要] 目的 探讨多种血液净化方法联用并结合护理干预在尿毒症CKD-MBD治疗中的临床效果。 方法 方便选取2017年1月—2018年12月在该院接受治疗的52例尿毒症患者作为该次实验的研究对象，随机分为两组，每组26例。对照组采用血液透析方法(HD)治疗及干预手段，观察组采用多种血液净化结合护理干预，即血液透析与血液透析滤过(HD+HDF)联合治疗。对比分析两组患者的临床效果情况。结果 观察组(第2、4阶段)PTH[(338.54±148.21)、(289.02±147.23)pg/mL]及血磷[(1.92±0.51)、(1.52±0.42)mmol/L]指标改善方面，明显优于对照组[(469.85±150.47)、(425.25±149.52)pg/mL，(2.49±0.78)、(2.21±0.65)mmol/L](t=13.891、16.654、5.701、8.625，P<0.05);且该组患者的临床症状[血压：(14.52±2.11) kPa;骨痛：1例;营养不良：2例;胸闷心慌：1例;皮肤瘙痒：0例]也明显优于对照组[血压：(20.12±2.21) kPa;骨痛：4例;营养不良：7例;胸闷心慌：5例;皮肤瘙痒：3例](t=13.659， χ2=0.996、1.680、1.507、0.979，P<0.05)。结论 采用多种血液净化方法联用并结合护理干预对尿毒症CKD-MBD临床效果显著，且能有效改善患者治疗后的临床症状，值得进一步应用推广。
[关键词] 血液净化;尿毒症;血液透析;血液透析滤过;护理干预
[中图分类号] R473 [文献标识码] A [文章编号] 1674-0742(2019)11(b)-0157-03
[Abstract] Objective To explore the clinical effects of multiple blood purification methods combined with nursing intervention in the treatment of uremia CKD-MBD. Methods A total of 52 uremic patients who were treated in the hospital from January 2017 to December 2018 were convenient selected and enrolled in this study. They were randomly divided into two groups， 26 cases in each group. The control group was treated with hemodialysis (HD) and intervention. The observation group used a variety of blood purification combined with nursing intervention， namely hemodialysis combined with hemodiafiltration (HD+HDF). The clinical effects of the two groups of patients were compared and analyzed. Results In the observation group (stages 2 and 4)， the improvement of PTH [(338.54±148.21)，(289.02±147.23)pg/mL]and blood phosphorus [(1.92±0.51)，(1.52±0.42)mmol/L]was significantly better than that of the control group [(469.85±150.47)，(425.25±149.52)pg/mL，(2.49±0.78)，(2.21±0.65)mmol/L] (t=13.891，16.654，5.701，8.625，P<0.05); and the clinical symptoms of this group of patients [blood pressure：(14.52 ± 2.11) kPa; bone pain： 1 cases; malnutrition： 2 cases; chest tightness palpitation： 1 cases; skin itching： 0 cases]， also significantly better than the control group [blood pressure： (20.12 ± 2.21)kPa; bone pain： 4 cases; malnutrition： 7 cases; chest tightness palpitation： 5 cases; skin itching： 3 cases](t=13.659， χ2=0.996，1.680，1.507，0.979，P<0.05). Conclusion The combination of multiple blood purification methods combined with nursing interven
尿毒癥处于各种肾脏类疾病的终末期，极难治愈，只能通过长期的血液透析来维持生命[1]。血液透析虽然能延缓患者病情，但治疗过程中极易产生各种并发症，且极为痛苦[2]。临床应用血液透析治疗尿毒症时虽能起到一定程度疗效，但在毒性物质清除方面还存在极大缺陷[3]。为提高尿毒症患者血液透析治疗的临床效果，该文方便选取2017年1月—2018年12月在该院接受治疗的52例尿毒症患者为研究对象，就多种血液净化方法联用并结合护理干预对提高尿毒症临床疗效课题进行了专项研究，现报道如下。, http://www.100md.com(丁俊 王婧)
[关键词] 血液净化;尿毒症;血液透析;血液透析滤过;护理干预
[中图分类号] R473 [文献标识码] A [文章编号] 1674-0742(2019)11(b)-0157-03
[Abstract] Objective To explore the clinical effects of multiple blood purification methods combined with nursing intervention in the treatment of uremia CKD-MBD. Methods A total of 52 uremic patients who were treated in the hospital from January 2017 to December 2018 were convenient selected and enrolled in this study. They were randomly divided into two groups， 26 cases in each group. The control group was treated with hemodialysis (HD) and intervention. The observation group used a variety of blood purification combined with nursing intervention， namely hemodialysis combined with hemodiafiltration (HD+HDF). The clinical effects of the two groups of patients were compared and analyzed. Results In the observation group (stages 2 and 4)， the improvement of PTH [(338.54±148.21)，(289.02±147.23)pg/mL]and blood phosphorus [(1.92±0.51)，(1.52±0.42)mmol/L]was significantly better than that of the control group [(469.85±150.47)，(425.25±149.52)pg/mL，(2.49±0.78)，(2.21±0.65)mmol/L] (t=13.891，16.654，5.701，8.625，P<0.05); and the clinical symptoms of this group of patients [blood pressure：(14.52 ± 2.11) kPa; bone pain： 1 cases; malnutrition： 2 cases; chest tightness palpitation： 1 cases; skin itching： 0 cases]， also significantly better than the control group [blood pressure： (20.12 ± 2.21)kPa; bone pain： 4 cases; malnutrition： 7 cases; chest tightness palpitation： 5 cases; skin itching： 3 cases](t=13.659， χ2=0.996，1.680，1.507，0.979，P<0.05). Conclusion The combination of multiple blood purification methods combined with nursing interven
尿毒癥处于各种肾脏类疾病的终末期，极难治愈，只能通过长期的血液透析来维持生命[1]。血液透析虽然能延缓患者病情，但治疗过程中极易产生各种并发症，且极为痛苦[2]。临床应用血液透析治疗尿毒症时虽能起到一定程度疗效，但在毒性物质清除方面还存在极大缺陷[3]。为提高尿毒症患者血液透析治疗的临床效果，该文方便选取2017年1月—2018年12月在该院接受治疗的52例尿毒症患者为研究对象，就多种血液净化方法联用并结合护理干预对提高尿毒症临床疗效课题进行了专项研究，现报道如下。, http://www.100md.com(丁俊 王婧)