中重度妊高症硫酸镁负荷治疗分析(1)
[摘要] 目的 探究中重度妊高症硫酸镁负荷治疗效果。方法 便利抽取2018年5月—2019年5月在该院接受治疗的中重度妊高症孕妇58例，按照其住院占后顺序将其按1～58的顺序编号，再按等差数列首项为1，公差为6的方式将58例孕妇平均分为两组，即对照组与实验组，每组均为29例。实验组孕妇给予负荷剂量硫酸镁，再静脉维持，必要时晚间肌注。對照组孕妇不给负荷剂量。对比两组孕妇的血压、并发症、分娩方式、羊水性质、Apgar评分等。结果 两组孕妇经过中重度妊高症治疗后，第1、2、3的收缩压和舒张压都有所下降，且实验组下降幅度比较大(t=2.891、4.341、1.967、3.398、2.698、4.266，P<0.05);实验组新生儿1 min阿氏评分0～3分、4～7分、8～10分别占0.00%、13.79%、86.20%，羊水性质为清、Ⅰ、Ⅱ、Ⅲ级孕妇均为3.44%、55.17%、37.93%、6.83%，对照组新生儿1 min阿氏评分0～3分、4～7分、8～10分别占6.89%、37.93%、55.47%，羊水性质为清、Ⅰ、Ⅱ、Ⅲ级孕妇均为0.00%、58.62%、27.58%、13.76%，差异有统计学意义(χ2=2.001、4.275、5.245、1.575、5.245、5.247、3.545，P<0.05)。结论 在中重度妊高症治疗过程中，硫酸镁有重要作用，能够有效降低孕妇的收缩压和舒张压，提高新生儿1 min阿氏评分，对孕妇羊水产生的影响也比较小，值得推广。
[关键词] 中重度妊高症;硫酸镁;负荷治疗
[Abstract] Objective Convenient select To investigate the effect of magnesium sulfate treatment on moderate to severe pregnancy-induced hypertension. Methods Fifty-eight pregnant women with moderate to severe pregnancy-induced hypertension who were treated in the hospital from May 2018 to May 2019 were numbered in the order of 1-58 according to their post-occupation order， and the first item in the equal difference series was 1. The method with a tolerance of 6 divides 58 pregnant women into two groups， namely the control group and the experimental group， each group having 29 cases. Pregnant women in the experimental group were given a loading dose of magnesium sulfate and then maintained intravenously， with intramuscular injection at night if necessary. Pregnant women in the control group were not given a loading dose. The blood pressure， complications， delivery methods， amniotic fluid properties， Apgar score of the two groups of pregnant women were compared. Results After treatment of moderate to severe pregnancy-induced hypertension in both groups， the systolic and diastolic blood pressures in the first， second， and third decreased， and the decline in the experimental group was relatively large(t= 2.891， 4.341， 1.967， 3.398， 2.698， 4.266， P<0.05); In the experimental group， the Amin scores of 0 to 3， 4 to 7， and 8 to 10 account for 0.00%， 13.79%， and 86.20%， respectively. The pregnant women were 3.44%，55.17%， 37.93%， and 6.83%. In the control group， the 1-minute A1 score of 0～3， 4～7， and 8～10 accounted for 6.89%， 37.93%， and 55.47%， respectively. The pregnant women of grades Ⅰ， Ⅱ， and Ⅲ were all 0.00%， 58.62%， 27.58%， and 13.76%，the difference was statistically significant(χ2=2.001， 4.275， 5.245， 1.575， 5.245， 5.247， 3.545， P<0.05).Conclusion Magnesium sulfate has an important role in the treatment of moderate to severe pregnancy-induced hypertension. It can effectively reduce the systolic and diastolic blood pressure of pregnant women and increase the 1-minute Aspergill score of the newborn., http://www.100md.com(宋媚淑)
[关键词] 中重度妊高症;硫酸镁;负荷治疗
[Abstract] Objective Convenient select To investigate the effect of magnesium sulfate treatment on moderate to severe pregnancy-induced hypertension. Methods Fifty-eight pregnant women with moderate to severe pregnancy-induced hypertension who were treated in the hospital from May 2018 to May 2019 were numbered in the order of 1-58 according to their post-occupation order， and the first item in the equal difference series was 1. The method with a tolerance of 6 divides 58 pregnant women into two groups， namely the control group and the experimental group， each group having 29 cases. Pregnant women in the experimental group were given a loading dose of magnesium sulfate and then maintained intravenously， with intramuscular injection at night if necessary. Pregnant women in the control group were not given a loading dose. The blood pressure， complications， delivery methods， amniotic fluid properties， Apgar score of the two groups of pregnant women were compared. Results After treatment of moderate to severe pregnancy-induced hypertension in both groups， the systolic and diastolic blood pressures in the first， second， and third decreased， and the decline in the experimental group was relatively large(t= 2.891， 4.341， 1.967， 3.398， 2.698， 4.266， P<0.05); In the experimental group， the Amin scores of 0 to 3， 4 to 7， and 8 to 10 account for 0.00%， 13.79%， and 86.20%， respectively. The pregnant women were 3.44%，55.17%， 37.93%， and 6.83%. In the control group， the 1-minute A1 score of 0～3， 4～7， and 8～10 accounted for 6.89%， 37.93%， and 55.47%， respectively. The pregnant women of grades Ⅰ， Ⅱ， and Ⅲ were all 0.00%， 58.62%， 27.58%， and 13.76%，the difference was statistically significant(χ2=2.001， 4.275， 5.245， 1.575， 5.245， 5.247， 3.545， P<0.05).Conclusion Magnesium sulfate has an important role in the treatment of moderate to severe pregnancy-induced hypertension. It can effectively reduce the systolic and diastolic blood pressure of pregnant women and increase the 1-minute Aspergill score of the newborn., http://www.100md.com(宋媚淑)