精液常规检验在男性不育诊疗中的应用评价(1)
[摘要] 目的 探讨在男性不育诊疗中进行精液常规检验的临床价值。方法 方便选取1 593例该所接收的男性不育患者,时间为2013年8月—2018年8月期间,患者禁欲2~7 d,手淫法取精,收集完整精液于清洁盖的小杯内,采用北京伟力WLJY-9000彩色精子质量检测系统,检测精子活力、精子密度等。 结果 1 593份不育患者精液检查所有参数均正常的占29.8%(475/1 593),有一项或多项参数异常的占70.2%(1 118/1 593)。异常组与正常组PH值和精液量比较,差异无统计学意义(t=0.742、-1.171,P>0.05);异常组与正常组精液液化时间、精子数、精子总活力、前向运动力比较,差异有统计学意义(t=-34.527、38.432、28.699、17.234,P<0.05);1 118例异常精液标本中,异常率最高的指标为精子总活力,占22.9%;除去无精子患者,共1 098例患者分为4個年龄段,在这4组间,其中>40岁年龄组前向运动百分率、精液浓度及精子总活力均较其他3个年龄组要低,且呈相对下降趋势(F=10.471、24.547、11.895,P<0.05);经单因素方差分析显示,PH值和精液量、精子正常形态率比较,差异无统计学意义(F=1.341、1.524、2.956,P>0.05);>40岁年龄组患者精液异常率最高,明显高于其他年龄组(χ2=11.391、19.321、16.781,P<0.05)。结论 男性不育患者中精子活力异常比例较高,此外年龄与男性精液质量有一定影响。
[关键词] 男性不育;精液常规检验;精子活力
[中图分类号] R271.14 [文献标识码] A [文章编号] 1674-0742(2020)03(a)-0192-03
Evaluation of Routine Semen Testing in Diagnosis and Treatment of Male Infertility
LAI Zhi-run
Fujian Institute of Family Planning Science and Technology, Fuzhou, Fujian Province, 350011 China
[Abstract] Objective To investigate the clinical value of routine semen testing in the diagnosis and treatment of male infertility. Methods A total of 1 593 male infertile patients received were conrenient selected from August 2013 to August 2018. The patients were abstained for 2~7 d, masturbation was used to extract sperm, and the complete semen was collected in a small cup with a clean lid. Beijing Weili WLJY-9000 color sperm quality detection system was used to detect sperm motility and sperm density. Results The parameters of semen examination of 1 593 infertile patients were normal (29.8% (475/1593)), and one or more parameters were abnormal 70.2% (1 118/1 593). There was no statistically significant difference in PH value and semen volume between the abnormal group and the normal group (t=0.742,-1.171 P>0.05); the semen liquefaction time, sperm count, total sperm motility, and forward motility were compared between the abnormal group and the normal group. The differences were statistically significant (t=-34.527, 38.432, 28.699, 17.234, P<0.05); among the 1 118 abnormal semen specimens, the highest abnormality index was the total sperm motility, which accounted for 22.9%; except for patients with sperm, a total of 1 098 patients were divided into 4 age groups. Among these 4 groups, the percentage of forward exercise, semen concentration, and total sperm motility of the> 40-year-old group were lower than those of the other three age groups, and they showed a relative downward trend(F=10.471, 24.547, 11.895, P<0.05); analysis of univariate analysis of variance showed that there was no statistically significant difference between PH value and semen volume and normal sperm morphology rate (F=1.341, 1.524, 2.956, P>0.05 ); the semen abnormality rate was highest in the> 40-year-old group, which was significantly higher than in other age groups(χ2=11.391, 19.321, 16.781, P<0.05). Conclusion The abnormal proportion of sperm motility is higher in male infertile patients, and age and male semen quality have a certain effect., http://www.100md.com(赖智润)
[关键词] 男性不育;精液常规检验;精子活力
[中图分类号] R271.14 [文献标识码] A [文章编号] 1674-0742(2020)03(a)-0192-03
Evaluation of Routine Semen Testing in Diagnosis and Treatment of Male Infertility
LAI Zhi-run
Fujian Institute of Family Planning Science and Technology, Fuzhou, Fujian Province, 350011 China
[Abstract] Objective To investigate the clinical value of routine semen testing in the diagnosis and treatment of male infertility. Methods A total of 1 593 male infertile patients received were conrenient selected from August 2013 to August 2018. The patients were abstained for 2~7 d, masturbation was used to extract sperm, and the complete semen was collected in a small cup with a clean lid. Beijing Weili WLJY-9000 color sperm quality detection system was used to detect sperm motility and sperm density. Results The parameters of semen examination of 1 593 infertile patients were normal (29.8% (475/1593)), and one or more parameters were abnormal 70.2% (1 118/1 593). There was no statistically significant difference in PH value and semen volume between the abnormal group and the normal group (t=0.742,-1.171 P>0.05); the semen liquefaction time, sperm count, total sperm motility, and forward motility were compared between the abnormal group and the normal group. The differences were statistically significant (t=-34.527, 38.432, 28.699, 17.234, P<0.05); among the 1 118 abnormal semen specimens, the highest abnormality index was the total sperm motility, which accounted for 22.9%; except for patients with sperm, a total of 1 098 patients were divided into 4 age groups. Among these 4 groups, the percentage of forward exercise, semen concentration, and total sperm motility of the> 40-year-old group were lower than those of the other three age groups, and they showed a relative downward trend(F=10.471, 24.547, 11.895, P<0.05); analysis of univariate analysis of variance showed that there was no statistically significant difference between PH value and semen volume and normal sperm morphology rate (F=1.341, 1.524, 2.956, P>0.05 ); the semen abnormality rate was highest in the> 40-year-old group, which was significantly higher than in other age groups(χ2=11.391, 19.321, 16.781, P<0.05). Conclusion The abnormal proportion of sperm motility is higher in male infertile patients, and age and male semen quality have a certain effect., http://www.100md.com(赖智润)
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