宫腔镜联合雌孕激素治疗人工流产术后宫腔粘连的临床价值研究(1)
[摘要] 目的 研究宫腔镜联合雌孕激素治疗人工流产术后宫腔粘连的临床价值。方法 随机选取2017年9月—2019年9月期间在该院接受治疗的人工流产术后发生宫腔粘连患者86例，将所有患者采取电脑随机选取方式进行分组，共分成观察组和对照组，各 43例患者，对照组采用宫腔镜进行治疗;观察组采用宫腔镜联合雌孕激素进行治疗，将两种治疗方法的最终效果进行对比。结果 同治疗后的对照组治疗总有效率及再粘连发生率的86.0%和18.6%比较，观察组患者治疗总有效率明显提高，数据结果为97.7%，且再粘连发生率仅为4.7%，上述指标对比差异有统计学意义(χ2=3.888、4.074，P<0.05)。观察组与对照组生活质量评分各为(95.21±3.34)分、(86.84±3.71)分，两组评分对比差异有统计学意义(t=10.995，P<0.05)，觀察组性激素各指标水平分别为卵泡生成激(10.2±1.8)pmol/L、雌二醇(422.1±45.5)mIU/mL、孕酮(2.9±0.9)pmol/L、黄体生成激素(58.3±8.5)mIU/mL;对照组上述相应指标各为(9.3±1.0)pmol/L、(273.2±28.9)mIU/mL、(5.4±1.1)pmol/L、(33.4±6.7)mIU/mL，两组之间数据比较差异有统计学意义(t=2.866、18.114、11.534、15.086，P<0.05)。 结论 对人工流产术后宫腔粘连患者采取宫腔镜联合雌孕激素治疗，可有效提高临床治疗效果，减少患者宫腔再次粘连发生，从而帮助患者改善生活质量。
[关键词] 宫腔镜;雌孕激素;人工流产术;宫腔粘连
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2020)08(b)-0010-04
Clinical Value of Hysteroscopy Combined with Estrogen and Progesterone in the Treatment of Intrauterine Adhesions after Artificial Abortion
LU Yan-rong，SONG Zhen
Yanggu County People's Hospital，Liaocheng，Shandong Province，252300 China
[Abstract] Objective To study the clinical value of hysteroscopy combined with estrogen and progesterone in the treatment of intrauterine adhesions after artificial abortion. Methods Randomly select 86 patients with intrauterine adhesions after artificial abortion treated in our hospital from September 2017 to September 2019. All patients were randomly selected by computer and grouped into observation group and control group. There were 43 patients in each group，and the control group was treated with hysteroscopy; the observation group was treated with hysteroscopy combined with estrogen and progesterone，and the final effects of the two treatment methods were compared. Results Compared with 86.0% and 18.6% of the total effective rate of treatment and the incidence of re-adhesion in the control group after treatment，the total effective rate of treatment in the observation group was significantly improved，the data result reached 97.7%，and the incidence of re-adhesion was only 4.7%，the comparison of the above indicators were statistically significant(χ2=3.888，4.074，P<0.05). The quality of life scores of the observation and control groups were (95.21±3.34)points and (86.84±3.71) points respectively. The difference between the scores of the two groups was large(t=10.995，P<0.05). The levels of sex hormones in the observation group were follicular stimulation(10.2±1.8)pmol/L，estradiol (422.1±45.5)mIU/mL，progesterone (2.9±0.9) pmol/L，luteinizing hormone (58.3±8.5) mIU/mL; the control group corresponds to the above indicators were (9.3±1.0) pmol/L，(273.2±28.9) mIU/mL，(5.4±1.1) pmol/L，(33.4±6.7) mIU/mL，and the data difference between the two groups was statistically significant (t=2.866，18.114，11.534，15.086，P<0.05). Conclusion Hysteroscopy combined with estrogen and progesterone treatment for patients with intrauterine adhesions after artificial abortion can effectively improve the clinical treatment effect and reduce the occurrence of re-adhesion in the uterine cavity，thus helping patients improve their quality of life., http://www.100md.com(鲁延荣 宋珍)
[关键词] 宫腔镜;雌孕激素;人工流产术;宫腔粘连
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2020)08(b)-0010-04
Clinical Value of Hysteroscopy Combined with Estrogen and Progesterone in the Treatment of Intrauterine Adhesions after Artificial Abortion
LU Yan-rong，SONG Zhen
Yanggu County People's Hospital，Liaocheng，Shandong Province，252300 China
[Abstract] Objective To study the clinical value of hysteroscopy combined with estrogen and progesterone in the treatment of intrauterine adhesions after artificial abortion. Methods Randomly select 86 patients with intrauterine adhesions after artificial abortion treated in our hospital from September 2017 to September 2019. All patients were randomly selected by computer and grouped into observation group and control group. There were 43 patients in each group，and the control group was treated with hysteroscopy; the observation group was treated with hysteroscopy combined with estrogen and progesterone，and the final effects of the two treatment methods were compared. Results Compared with 86.0% and 18.6% of the total effective rate of treatment and the incidence of re-adhesion in the control group after treatment，the total effective rate of treatment in the observation group was significantly improved，the data result reached 97.7%，and the incidence of re-adhesion was only 4.7%，the comparison of the above indicators were statistically significant(χ2=3.888，4.074，P<0.05). The quality of life scores of the observation and control groups were (95.21±3.34)points and (86.84±3.71) points respectively. The difference between the scores of the two groups was large(t=10.995，P<0.05). The levels of sex hormones in the observation group were follicular stimulation(10.2±1.8)pmol/L，estradiol (422.1±45.5)mIU/mL，progesterone (2.9±0.9) pmol/L，luteinizing hormone (58.3±8.5) mIU/mL; the control group corresponds to the above indicators were (9.3±1.0) pmol/L，(273.2±28.9) mIU/mL，(5.4±1.1) pmol/L，(33.4±6.7) mIU/mL，and the data difference between the two groups was statistically significant (t=2.866，18.114，11.534，15.086，P<0.05). Conclusion Hysteroscopy combined with estrogen and progesterone treatment for patients with intrauterine adhesions after artificial abortion can effectively improve the clinical treatment effect and reduce the occurrence of re-adhesion in the uterine cavity，thus helping patients improve their quality of life., http://www.100md.com(鲁延荣 宋珍)