探讨牙周基础治疗对2型糖尿病伴牙周病患者的影响(1)
[摘要] 目的 探究牙周基础治疗对2型糖尿病伴牙周病患者的临床影响。方法 方便选取2018年11月—2019年12月期间该院收治的84例2型糖尿病伴牙周病患者参与该次研究，根据抽签法进行随机分组，包括对照组(n=42)和观察组(n=42)。对照组患者采用常规治疗，观察组患者采用牙周基础治疗，比较两组患者治疗后血糖水平、炎性因子水平和牙周健康指标。结果 观察组患者治疗后的PLI(2.75±0.11)分、PD(2.14±0.13)mm、AL(3.16±0.34)mm、BOPR(0.15±0.04)%、FBG(7.58±0.62)mmol/L、HbAlc(7.33±0.41)%、TNF-α(8.82±0.42)pg/mL、hs-CRP(2.47±1.13)mg/L均低于对照组(3.04±0.16)分、(2.68±0.21) mm、(3.55±0.35)mm、(0.27±0.12)%、(9.34±1.15)mmol/L、(8.47±0.68)%、(13.06±0.55)pg/mL、(3.84±1.25)mg/L，经比较差异有统计学意义(t=9.679、14.169、5.179、6.148、8.730、9.304、39.707、5.269，P<0.05)。 结论 牙周基础治疗能够有效维持2型糖尿病伴牙周病患者的血糖水平，促进炎性因子水平下降，维护其牙周健康。
[关键词] 牙周基础治疗;2型糖尿病;牙周病;糖脂代谢
[中图分类号] R781.4 [文献标识码] A [文章編号] 1674-0742(2020)09(c)-0065-03
[Abstract] Objective To explore the clinical effects of basic periodontal treatment on patients with type 2 diabetes and periodontal disease. Methods A total of 84 patients with type 2 diabetes and periodontal disease who were admitted to the hospital from November 2018 to December 2019 were conveniently selected to participate in this study， and randomized according to the lottery method， including the control group (n=42) and the observation group (n=42). Patients in the control group received conventional treatment， and patients in the observation group received basic periodontal treatment. The blood glucose levels， inflammatory factor levels and periodontal health indicators were compared between the two groups after treatment. Results PLI (2.75±0.11)points， PD (2.14±0.13)mm， AL (3.16±0.34)mm， BOPR (0.15±0.04)%， FBG (7.58±0.62)mmol/L， HbAlc (7.33±0.41)%， TNF-α (8.82±0.42)pg/mL， hs-CRP (2.47±1.13)mg/L， lower than the control group (3.04±0.16)points， (2.68±0.21)mm， (3.55±0.35)mm， (0.27±0.12)%， (9.34±1.15)mmol/L， (8.47±0.68)%， (13.06±0.55)pg/mL， (3.84±1.25)mg/L， the difference was statistically significant (t=9.679， 14.169， 5.179， 6.148， 8.730， 9.304， 39.707， 5.269， P<0.05). Conclusion basic periodontal treatment can effectively maintain the blood sugar level of patients with type 2 diabetes and periodontal disease， promote the decline of inflammatory factors， and maintain their periodontal health.
[Key words] Basic periodontal treatment; Type 2 diabetes; Periodontal disease; Glucose and lipid metabolism
牙周病是临床常见口腔科疾病，会导致患者牙齿松动和脱落，对其口腔健康造成很大影响，同时其对患者冠心病、糖尿病等慢性疾病也存在一定的不良影响，并且糖尿病、冠心病等慢性病患者并发牙周病风险相比健康人群显著更高[1-2]。由于糖尿病和牙周病之间相互影响的关系，导致 2型糖尿病伴发牙周病患者的治疗难度有所上升，该类疾病患者治疗耐受性较差，须多开展非手术牙周病治疗方案。有研究显示，糖尿病伴发牙周病患者的临床治疗中需要兼顾牙周病的治疗和血糖水平的控制，以提升患者的临床疗效和生活质量[3-4]。该次方便择取2018年11月—2019年12月期间该院收治的84例2型糖尿病伴牙周病患者开展不同疗法的疗效研究，现报道如下。, http://www.100md.com(刘瑞玲)
[关键词] 牙周基础治疗;2型糖尿病;牙周病;糖脂代谢
[中图分类号] R781.4 [文献标识码] A [文章編号] 1674-0742(2020)09(c)-0065-03
[Abstract] Objective To explore the clinical effects of basic periodontal treatment on patients with type 2 diabetes and periodontal disease. Methods A total of 84 patients with type 2 diabetes and periodontal disease who were admitted to the hospital from November 2018 to December 2019 were conveniently selected to participate in this study， and randomized according to the lottery method， including the control group (n=42) and the observation group (n=42). Patients in the control group received conventional treatment， and patients in the observation group received basic periodontal treatment. The blood glucose levels， inflammatory factor levels and periodontal health indicators were compared between the two groups after treatment. Results PLI (2.75±0.11)points， PD (2.14±0.13)mm， AL (3.16±0.34)mm， BOPR (0.15±0.04)%， FBG (7.58±0.62)mmol/L， HbAlc (7.33±0.41)%， TNF-α (8.82±0.42)pg/mL， hs-CRP (2.47±1.13)mg/L， lower than the control group (3.04±0.16)points， (2.68±0.21)mm， (3.55±0.35)mm， (0.27±0.12)%， (9.34±1.15)mmol/L， (8.47±0.68)%， (13.06±0.55)pg/mL， (3.84±1.25)mg/L， the difference was statistically significant (t=9.679， 14.169， 5.179， 6.148， 8.730， 9.304， 39.707， 5.269， P<0.05). Conclusion basic periodontal treatment can effectively maintain the blood sugar level of patients with type 2 diabetes and periodontal disease， promote the decline of inflammatory factors， and maintain their periodontal health.
[Key words] Basic periodontal treatment; Type 2 diabetes; Periodontal disease; Glucose and lipid metabolism
牙周病是临床常见口腔科疾病，会导致患者牙齿松动和脱落，对其口腔健康造成很大影响，同时其对患者冠心病、糖尿病等慢性疾病也存在一定的不良影响，并且糖尿病、冠心病等慢性病患者并发牙周病风险相比健康人群显著更高[1-2]。由于糖尿病和牙周病之间相互影响的关系，导致 2型糖尿病伴发牙周病患者的治疗难度有所上升，该类疾病患者治疗耐受性较差，须多开展非手术牙周病治疗方案。有研究显示，糖尿病伴发牙周病患者的临床治疗中需要兼顾牙周病的治疗和血糖水平的控制，以提升患者的临床疗效和生活质量[3-4]。该次方便择取2018年11月—2019年12月期间该院收治的84例2型糖尿病伴牙周病患者开展不同疗法的疗效研究，现报道如下。, http://www.100md.com(刘瑞玲)