老年胃食管反流病的研究进展(2)
老年人多首选创伤小的治疗手段,如改变生活方式和药物治疗。但对于部分病例反复发作,长期依赖制酸药物或症状无法缓解的患者,则需要考虑外科或胃镜下治疗。
5 展望
胃食管反流性疾病有逐年增长的趋势,老年人由于各种原因引起胃肠动力及酸清除能力减退,发病率更高。同时,老年患者GERD的症状不典型,难以与其他疾病相鉴别,容易延误诊治。日后,需要更加完善其检查手段,以及更强有效的制酸剂的问世和其他治疗手段的改进,使GERD的老年患者得到更有效的治疗,以提高其生活质量。
[参考文献]
[1]Fass R,Ofmen JJ.Gastroesophageal reflux disease-should we adopt a new conceptual framework[J].Am J Gastroenterol,2002,97:1901-1909.
[2]Rhodes J,Bernardo DE,Philips SF,et al.Increased reflux of bile into the stomach in patients with gastric ulcer[J].Gastroentenology,1997,57:241-252.
[3]Jonaitis V,Kiudelis G,Kupcinskas L.Characteristics of patients with erosive and nonerosive GERD in high-helicobacter-pylori prevalence region[J].Dis Esophagus,2004,17(3):223.
[4]姜跃龙,刘新光,许乐.老年反流性食管炎患者幽门螺旋杆菌感染率调查[J].中华老年医学杂志,2006,25(12):908-909.
[5]Manterola C,Munoz S,Grande L,et al.Initial validation of a questionnaire for detecting gastroesophageal reflux diease in epidemiological settings[J].J Clin Epidemiol,2002,55(10):1041-1045.
[6]Pandak WM, Arezo S,Everett S,et al.Short course of omeprazole: abetter first diagnostic approach to noncardiac chest pain than endoscopy, manometry, or 24-hour esophageal PH monitoring[J].J Clin Gastroenerol,2002,35:307-314.
[7]Armstrong D,Benntt JR,Blum AL, et al.The endoscopic assessment of esophagitis: a progress report on observer agreement[J].Gastroenterology,1996,111:85-92.
[8]wain P,Broun G,Gong F,et al.Anendoscopically deliverable tessue- transfixing device for securing biosens ors in the gastrointestinal tract[J].Gastrointest Endosc,1994,40:730-734.
[9]李建业,刘宾.胃镜下胃黏膜折叠缝合术治疗胃食管反流疾病[J].北京医学,2005,27(3):132-134.
[10]廖专,李兆申.胃食管反流病的内镜治疗进展[J].国外医学·消化系疾病分册,2004,24(3):156-159.
(收稿日期:2009-05-25), 百拇医药
5 展望
胃食管反流性疾病有逐年增长的趋势,老年人由于各种原因引起胃肠动力及酸清除能力减退,发病率更高。同时,老年患者GERD的症状不典型,难以与其他疾病相鉴别,容易延误诊治。日后,需要更加完善其检查手段,以及更强有效的制酸剂的问世和其他治疗手段的改进,使GERD的老年患者得到更有效的治疗,以提高其生活质量。
[参考文献]
[1]Fass R,Ofmen JJ.Gastroesophageal reflux disease-should we adopt a new conceptual framework[J].Am J Gastroenterol,2002,97:1901-1909.
[2]Rhodes J,Bernardo DE,Philips SF,et al.Increased reflux of bile into the stomach in patients with gastric ulcer[J].Gastroentenology,1997,57:241-252.
[3]Jonaitis V,Kiudelis G,Kupcinskas L.Characteristics of patients with erosive and nonerosive GERD in high-helicobacter-pylori prevalence region[J].Dis Esophagus,2004,17(3):223.
[4]姜跃龙,刘新光,许乐.老年反流性食管炎患者幽门螺旋杆菌感染率调查[J].中华老年医学杂志,2006,25(12):908-909.
[5]Manterola C,Munoz S,Grande L,et al.Initial validation of a questionnaire for detecting gastroesophageal reflux diease in epidemiological settings[J].J Clin Epidemiol,2002,55(10):1041-1045.
[6]Pandak WM, Arezo S,Everett S,et al.Short course of omeprazole: abetter first diagnostic approach to noncardiac chest pain than endoscopy, manometry, or 24-hour esophageal PH monitoring[J].J Clin Gastroenerol,2002,35:307-314.
[7]Armstrong D,Benntt JR,Blum AL, et al.The endoscopic assessment of esophagitis: a progress report on observer agreement[J].Gastroenterology,1996,111:85-92.
[8]wain P,Broun G,Gong F,et al.Anendoscopically deliverable tessue- transfixing device for securing biosens ors in the gastrointestinal tract[J].Gastrointest Endosc,1994,40:730-734.
[9]李建业,刘宾.胃镜下胃黏膜折叠缝合术治疗胃食管反流疾病[J].北京医学,2005,27(3):132-134.
[10]廖专,李兆申.胃食管反流病的内镜治疗进展[J].国外医学·消化系疾病分册,2004,24(3):156-159.
(收稿日期:2009-05-25), 百拇医药