来氟米特对糖尿病肾病大鼠肾脏VEGF表达的影响(3)
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总之,VEGF在DN的发生及发展中起到一定的致病作用。本研究结果证实来氟米特对DN模型的VEGF表达具有一定的调节作用,可以减轻肾脏病变程度及延缓DN向终末期进展,但其具体作用机制有待于进一步研究。
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