无创正压通气治疗COPD合并Ⅱ型呼吸衰竭临床效果分析(1)
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2010年6月25日
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[摘要] 目的:采用回顾性方法比较无创正压通气与有创通气治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭的临床效果,分析治疗的相关因素。方法:2006年1月1日～2008年12月31日,选取本院呼吸内科慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者71例,比较无创正压通气与有创通气治疗的血气和呼吸频率等指标的变化。结果:两组患者通气治疗12 h和通气治疗结束后,在呼吸频率、pH值、PaO2、PaCO2等指标与入院时比较均有改善(P<0.05);通气治疗12 h和结束后无创组和有创组在呼吸频率、pH值、PaO2指标方面差异无统计学意义(P>0.05),两组通气治疗结束后在PaCO2方面存在差异(P<0.05)。应用无创通气治疗时呼吸机相关性肺炎(VAP)的发生较低,无创组患者平均住院时间小于有创组患者。结论:无创正压通气治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭效果明显,且使用方便,患者易接受,还可缩短治疗时间,使部分患者能免于气管插管。
[关键词]无创正压通气;慢性阻塞性肺疾病;Ⅱ型呼吸衰竭
[中图分类号] R563.8 [文献标识码]A [文章编号]1674-4721(2010)06(c)-036-03
Clinical effects of non-invasive positive pressure ventilation and invasive ventilation in COPD with respiratory failure Ⅱ
ZHOU Jianhui,LIU Yang
(People's Hospital of Yiyang City,Hunan Province,Yiyang413001,China)
[Abstract] Objective:To compare retrospective non-invasive positive pressure ventilation and invasive ventilation in chronic obstructive pulmonary disease with respiratory failure Ⅱ clinical effects of treatment related factors. Methods:From January 1,2006 to December 31,2008, selected our hospital of respiratory medicine of chronic obstructive pulmonary disease with respiratory failure in patients with type Ⅱ, 71 cases of relatively non-invasive positive pressure ventilation and invasive ventilation in the treatment of blood gas and breathing frequency were observed. Results:There were ventilation, and ventilation 12 h after treatment, the respiratory rate, pH value, PaO2, PaCO2 other indicators had improved compared with admission (P<0.05); ventilation after 12 h, and invasive non-invasive groups and groups in respiratory rate, pH value, PaO2 indicators between the two groups was no significant difference (P>0.05), the two groups after the end of ventilation and there were differences in PaCO2 (P<0.05). Application of non-invasive ventilation with lower incidence of VAP treatment, non-invasive group were less than the average hospital stay of patients with invasive group. Conclusion:The non-invasive positive pressure ventilation in chronic obstructive pulmonary disease with respiratory failure Ⅱ effect is obvious, and easy to use, easily accepted by patients, but also shorten the treatment time to allow some patients to be free from tracheal intubation ......
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