LEEP在宫颈上皮内瘤样病变治疗中的效果研究(1)
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2010年7月5日
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[摘要] 目的:探讨宫颈环形电切术(LEEP)对宫颈上皮内瘤样病变的治疗效果。方法:采用LEEP术进行治疗宫颈上皮内瘤样病变(CIN)98例,将治疗前后的病理结果进行对比,记录术中情况及术后随访结果。结果:阴道镜活检病理结果与LEEP术后病理结果相符者61例,占62.3%,术后病理降级者22例,占22.4%,升级者15例,占15.3%。两组比较差异有统计学意义(P<0.01)。平均手术时间为6.7 min,常见的术后不良反应有阴道少量血性分泌物、阴道流血、月经期提前、低热。结论:LEEP手术时间短,术中出血量少,操作简便,对病理诊断无影响,治疗CIN效果良好,应注意手术操作手法,减少并发症的发生。
[关键词] 宫颈环形电切术;宫颈上皮内瘤样病变;治疗效果
[中图分类号] R711.74 [文献标识码]A [文章编号]1674-4721(2010)07(a)-051-02
LEEP in cervical intraepithelial lesions and effect of treatment
LIU Min,HE Qiu,XU Huixin,SUN Yali
(Panzhihua City in Sichuan Province General Hospital,climbing Coal Group Inc Panzhihua,Panzhihua 617066,China)
[Abstract] Objective:To investigate the cervical loop electrosurgical excision procedure (LEEP) for cervical intraepithelial lesions treatment.Methods:LEEP procedure for treatment of cervical intraepithelial lesions (CIN) 98 patients before and after the treatment of pathological results were compared,intraoperative conditions and postoperative follow-up results.Results:Colposcopy and LEEP biopsy results consistent with pathological findings in 61 cases,accounting for 62.3%,pathological downgrading in 22 cases,accounting for 22.4%,upgrade 15 cases,accounting for 15.3%.The two groups had significant difference (P<0.01).The mean operative time 6.7 min,after the common adverse reactions were,a small amount of bloody vaginal discharge,vaginal bleeding,menstrual period early,low heat.Conclusion:LEEP surgery a short time,less blood loss,easy operation,no effect on the pathological diagnosis,treatment CIN good effect,should be noted that operative techniques to reduce complications.
[Key words] Cervical loop electrosurgical excision procedure;Cervical intraepithelial lesion;Treatment
宫颈上皮内瘤样病变(cervical intraepithelial neoplasia,CIN)为癌前期病变,CIN发展为原位癌的风险是正常人的20倍,发展为宫颈浸润癌的风险是正常人的7倍。早期诊断与治疗CIN是降低宫颈癌发病率的关键[1]。宫颈环形电切术(loop electrosurgical excision procedure,LEEP)是一种非常精细的手术,不仅对周围组织无损伤,治疗过程无疼痛,术后不留瘢痕,且能较好地避免出血或感染等并发症[2]。笔者观察了LEEP对宫颈上皮内瘤样病变的治疗效果,现报道如下:
1资料与方法
1.1一般资料
选择本院2007年1月～2009年10月经宫颈薄层液基细胞学检查及病理活检诊断为宫颈上皮内瘤样病变者98例,年龄21～52岁,平均(34.5±6.8)岁; CINⅠ级38例,CINⅡ级44例,CINⅢ级16例。98例患者均行LEEP治疗,术后进行常规病理检查。
1.2 治疗方法 ......
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