[摘要] 目的：探讨急性重度有机磷中毒合并呼吸衰竭的机械通气效果。方法：对66例急性重度有机磷中毒合并呼吸衰竭患者给予急性气管插管、机械通气，选用SIMV+PSV模式，根据血气分析结果调整参数，并同时予清除毒物，阿托品、氯磷定等解毒药物应用及对症支持治疗等。结果：3例患者出现呼吸心跳骤停，死于循环功能衰竭，3例放弃治疗，其余60例治愈(90.9%)，机械通气时间18~145 h，平均46 h，住院6~20 d(平均9 d)，5例并发呼吸机相关性肺炎。结论：机械通气是抢救急性重度有机磷中毒的有力措施，对于提高该类患者的救治成功率有着非常重要的意义。

    [关键词] 有机磷农药中毒；呼吸衰竭；机械通气

    [中图分类号] R595.4 [文献标识码]A[文章编号]1674-4721(2011)02(b)-037-02

    The use of mechanical ventilation of severe organophosphorus insecticides poisoning patients

    XU Huiling

    (Department of Emergency, the First People's Hospital of Lianyungang City, Jiangsu Province, Lianyungang222000,China)

    [Abstract] Objective: To observe the effect of mechanical ventilation in the severe organophosphorus insecticides poisoning. Methods: 66 cases of severe organophosphorus insecticides poisoned patients, who intubed and mechanical ventilated emergency, the ventilation mode was SIMV+PSV, we adjust the parameter on the basis of blood gas analysis, at same time, clear the poison, used drugs like atropine and Pyraloxime Chloride. Results: 3 patients had cardiac arrest and died of the circulation failure, 3 patients gave up the therapy, 60 patients were cured(90.9%). The ventilation time were 18-145 hours ......