GE3.0T扩散加权成像高b值在前列腺癌和非癌组织中的诊断价值(1)
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[摘要] 目的：通过对前列腺中央带及外周带ADC值分析，研究其在前列腺癌和非癌组织中的诊断价值。方法：对43例前列腺疾病分类，分为增生组和癌变组，并选取正常对照组，b=1 500 s/mm2。并对正常组、增生组和癌变组的ADC值进行统计学分析。结果：GE3.0T扩散加权成像技术高b值得出的前列腺癌变的ADC值明显低于正常和增生的ADC值，其间比较差异有统计学意义；前列腺中央带和外周带癌变的ADC值差异无统计学意义。结论：GE3.0T扩散加权成像选用高b值得出的ADC值分析结果表明前列腺癌和非癌组织有明显差异，更助于诊断前列腺癌。
[关键词] 前列腺；前列腺癌；磁共振成像；扩散加权成像；表观扩散系数
[中图分类号] R737.25[文献标识码]A [文章编号]1674-4721(2011)04(c)-009-02
High b-values of diffusion-weighted MR Imaging in diagnosis of prostate cancerous and non-cancerous regions by GE3.0T
LIU Jie，ZHANG Hui
Department of Radiology , Shanxi Med University First Hospital，Shanxi Province, Taiyuan 030001, China
[Abstract] Objective: Through the central zone of the prostate peripheral zone and the ADC value analysis, research in prostate cancer and non cancer diagnosis. Methods: 43 cases of prostate disease classification, divided into two groups and the proliferation of cancer group, and selected the normal control group, b=1 500 s/mm2. And the normal group, hyperplasia group and cancer group, ADC values were analyzed statistically. Results: GE3.0T high-b diffusion-weighted imaging of prostate cancer worth the ADC was significantly lower than ADC values of normal and proliferation, during which there was significant difference; prostate central zone and peripheral zone cancer was no significant difference between ADC values. Conclusion: GE3.0T high-b diffusion-weighted imaging should be selected out of analysis showed that ADC values of prostate cancer and non-cancer tissues are significantly different, but also help to diagnose prostate cancer.
[Key words] Prostate; Prostatic carcinoma; MR imaging; Diffusion weighted imaging; Apparent diffusion coefficient
前列腺癌是老年男性最常见的恶性肿瘤[1-2]之一，而扩散加权成像(diffusion weighted imaging, DWI)作为磁共振功能成像中的一种，在前列腺疾病的诊断和研究中, 发挥着越来越重要的地位[3] 。DWI成像以其快速便捷的成像方式，通过反映自由水分子的随机运动状态，可以间接反映组织中水分子所处环境，对前列腺的组织结构和含水量及同年龄段不同的病理状态，特别是对诊断和鉴别前列腺疾病方面越来越受到国内外学者的重视。
1 资料与方法
1.1 一般资料
2010年6～12月在本院行MRI检查的前列腺患者，基本选取身体一般状况良好，无严重心血管病，无肝肾功能障碍，且未进行内分泌、放疗等治疗的患者。体内无金属物(起搏器、心脏支架、金属标记物、手术闭合器及人工瓣膜等) ......
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