中药灌肠联合抗生素治疗慢性前列腺炎的疗效观察
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[摘要] 目的：观察中药灌肠联合抗生素治疗慢性前列腺炎的临床疗效。方法：慢性前列腺炎患者176例，随机分成治疗组和对照组，分别给予中药灌肠联合抗生素治疗和单纯抗生素治疗，对比其临床疗效。结果：治疗组90例，治愈40例，有效36例，无效14例，总有效率为84.44%；对照组86例，治愈26例，有效25例，无效35例，总有效率为59.30%。两组比较差异有统计学意义(P<0.05)。结论：抗生素同时辅以中药灌肠治疗慢性前列腺炎能取得更好的疗效。
[关键词] 慢性前列腺炎；抗生素；中药；灌肠
[中图分类号] R697+.33 [文献标识码]B [文章编号]1674-4721(2011)05(c)-081-02
Clinical effect of enema with traditional Chinese medicine in combination with antibiotics in treatment of chronic prostatitis
HAN Tongbin1, HAN Baojian1, QIN Weiya2
1.Department of Urology, the Eighth People's Hospital of Qingdao, Shandong Province, Qingdao 266100, China; 2.Department of Pharmacy, the Eighth People's Hospital of Qingdao, Shandong Province, Qingdao 266100, China
[Abstract] Objective: To evaluate the effects of Enema with ttaditional Chinese medicine in combination with antibiotics in treatment of chronic prostatitis. Methods: 176 patients who were diagnosed as chronic prostatitis were randomly divided into study group (n=90) and control group (n=86). The former received of Enema with traditional Chinese medicine in combination with antibiotics treatment，and the latter only received antibiotics treatment. Results: There were 40 cases of patients were cured and 36 cases of patients were improved，the total effective rate was 84.44% in study group. There were 26 cases of patients were cured and 25 cases of patients were improved, the total effective rate was 59.30% in control group. Conclusion: Enema with traditional Chinese medicine in combination with antibiotics is a safe, effective way of treating chronic prostatitis.
[Key words] Chronic prostatitis; Antibiotics; Traditional Chinese medicine; Enema
慢性前列腺炎是男性生殖系统常见的炎性疾病，症状多样且经常反复发作，目前尚无准确的治疗方法及确切的治疗效果[1]。2009年9月~2010年8月，笔者采用中药灌肠联合抗生素治疗慢性前列腺炎患者90例，单独抗生素治疗86例，进行对比观察，现将结果报道如下：
1资料与方法
1.1一般资料
本组均符合慢性前列腺炎的诊断标准[2]。将就诊患者分为治疗组和对照组，按就诊顺序随机分配。治疗组90例，平均年龄30.2岁(18~52岁)；平均病史1.3年(3个月~8年)；慢性细菌性前列腺炎18例。对照组86例，平均年龄31.4岁(21~51岁)；平均病史1.5年(2.5~9年)；慢性细菌性前列腺炎16例。所有患者均有不同程度尿频、尿急、尿后有白色黏液滴出；有尿痛，腰骶部、会阴、小腹、睾丸胀痛或不适感；并经尿常规化验、B超及肛门指诊，排除尿路感染、结石及前列腺癌等疾病。两组患者在年龄、病程、病情方面具有可比性。
1.2 治疗方法
1.2.1 对照组：慢性细菌性前列腺炎患者根据病原体的不同结合药敏试验而采取不同的抗炎药物治疗，慢性非细菌性前列腺炎患者选取米诺环素。
1.2.2 治疗组：在对照组治疗基础上同时配合中药灌肠，采用桃红四物汤加减，药物组成：桃仁20 g，红花10 g，菊花10 g，丹参30 g，鱼腥草30 g，连翘30 g，地丁30 g，紫花30 g，当归20 g，煎成汤剂100 ml。待自然降温至39~40℃时，嘱患者大便后将一次性导尿管插入直肠腔内约7 cm，将药液经尿管注入直肠腔内行保留灌肠。注药后卧床1 h，1 h内不大便，每天灌肠1次。
上述治疗方法以15 d为1个疗程，治疗2个疗程后统计疗效。
1.3 疗效判定标准
①治愈：前列腺炎所有症状消失，前列腺液常规每个高倍镜视野WBC<10个，卵磷脂小体+++~++++。②好转：前列腺炎症状减轻，前列腺液常规WBC减少，卵磷脂小体增加。③无效：前列腺炎症状无改善，前列腺液检查结果无改善。
1.4统计学方法
采用SPSS 13.0统计软件包进行统计分析，采取卡方检验。P<0.05表明差异有统计学意义。
2 结果
治疗组90例，治愈40例，总有效率为84.44%；对照组86例，治愈26例，总有效率为59 ......
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