阻塞性睡眠呼吸暂停综合征对血糖\血脂的影响(1)
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[摘要] 目的：调查阻塞性睡眠呼吸暂停综合征(OSAS)伴血压升高患者在不同状态下血糖、血脂控制情况。方法：回顾性分析本院2008年3月～2010年5月门诊收治住院的111例30～70岁的患者临床资料，根据8 h的夜间睡眠呼吸监测(PSG)，根据呼吸暂停/低通气指数(AHI)分为两组。病患组71例，对照组40例，并对两组血糖、血脂数值进行比较分析。结果：病例组TC、FBG高于对照组(P<0.05)，低密度脂蛋白LDL较对照组高，但差异无统计学意义。结论：OSAS合并高血压患者出院后血压得到控制，但血糖和血脂有增高趋势；血压正常高值患者出院后血压、血糖、血脂均有增高趋势；OSAS伴高血压患者手术后血压水平得到改善。
[关键词] 阻塞性睡眠呼吸暂停综合征；血糖；血脂
[中图分类号] R56 [文献标识码]A[文章编号]1674-4721(2011)06(a)-046-02
Effect of obstructive sleep apnea syndrome on glucolipid abnormal metabolism
LIN Haitao1, MA Jing2
1. Department of Respiratory Medicine, Central Hospital of Changchun City, Jilin Province, Changchun130051,China; 2. Emergency Department, Changchun Municipal People's Hospital, Jilin Province, Changchun130051,China
[Abstract] Objective: To investigate obstructive sleep apnea syndrome (OSAS) patients with elevated blood pressure in a different state blood glucose and lipid control the situation. Methods: To analyze clinical data of 111 patients 30-70 year-old in our hospital from March 2008 to May 2010 retrospectively, according to 8 hours of nocturnal sleep apnea monitoring (PSG), apnea / hypopnea index (AHI) patients were divided into patient group(71 cases), control group (40 cases), and two groups of blood glucose, lipid profiles were compared. Results: In the patient group TC, FBG were higher than control group (P<0.05), LDL was higher than control group, but there was no significant difference. Conclusion: OSAS patients with hypertension and blood pressure under control after discharge, but tended to increase blood glucose and lipids; patients with high normal blood pressure after discharge, blood pressure, blood glucose, blood lipids have an increasing tendency; OSAS patients with hypertension with blood pressure levels improved after surgery.
[Key words] Obstructive sleep apnea syndrome; Blood glucose; Blood-fat
笔者选择本院2008年3月～2010年5月门诊收住院的111例30～70岁的患者研究对象，进行标准的多导睡眠呼吸监测，依据呼吸暂停/低通气指数(AHI)分为对照组和病例组比较各组之间糖脂水平的差异。
1 资料与方法
1.1 一般资料
选择长春市中心医院门诊及住院的111患者，均符合2003年中华医学会呼吸病学分会诊治指南诊断标准[1]，进行8 h的夜间睡眠呼吸监测，根据AHI结果分为病例组和对照组。其中，病例组71例，平均年龄为(37.30±6.90)岁，对照组40例，平均年龄为(36.63±6.51)岁。所有入选对象均除外严重心脑血管和肾脏并发症，排除慢性肺部病变、神经肌肉疾病、甲状腺疾病、营养代谢疾病及其他内分泌疾病和恶性肿瘤疾病等 ......
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