冷刀宫颈锥切术诊治宫颈上皮内瘤变的临床分析(1)
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[摘要] 目的:评价冷刀宫颈锥切术对宫颈上皮内瘤变(CIN)的诊治效果。方法:回顾性分析在本院接受诊治的93例宫颈上皮内瘤变癌患者的资料,对比宫颈锥切术和阴道镜下多点宫颈活检组织学诊断结果,评价它们术后的组织学发现和临床结果。结果:93例中有69例(74.2%)宫颈锥切和阴道镜多点活检的病理发现相符合,其余24例(25.8%)不符合。4例(4.3%)未完全切除,但复发率仅为2.2%,治愈率为97.8%。发现3例早期浸润癌。6例随后行子宫切除术。宫颈锥切术相关的主要并发症是出血和宫颈狭窄,5例(5.4%)发生出血,2例(2.2%)发生宫颈狭窄。结论:宫颈锥切诊断宫颈上皮内瘤变比阴道镜下多点活检更准确。宫颈锥切在治疗宫颈上皮内瘤变方面的作用也很重要,如果操作适当其并发症的风险低。它能在疾病诊治过程中提供一个正确的组织学依据,在许多病例中有临床价值。
[关键词] 宫颈上皮内瘤变;冷刀宫颈锥切术;活检;病理
[中图分类号] R737.33[文献标识码]B [文章编号]1674-4721(2011)06(b)-143-03
Diagnostic and therapeutic cold knife conization for cervical intraepithelial neoplasia
FENG Tianen, ZHAI Yaming
Department of 1ST Surgery, Kaifeng Tumour Hospital, Henan Province, Kaifeng 475003, China
[Abstract] Objective: To evaluate the diagnostic and therapeutic efficacy of using cold knife conization for cervical intraepithelial neoplasia (CIN). Methods: The data of 93 cases with CIN diagnosed and treated in our hospital were retrospectively analyzed. The histologic diagnoses from cervical conization and from colposcopic multiple punch biopsies were compared, and then their postoperative histologic findings and clinical outcomes were evaluated. Results: Of the 93 patients, there was a correlation in histologic findings between cervical conization and colposcopic multiple punch biopsies in 69 cases (74.2%), and there was no correlation in the other 24 cases (25.8%). Incomplete excision was performed in 4 cases (4.3%), but the failure rate was only 2.2%; the cure rate was 97.8%. Three cases with early invasive cancer were found. Six patients underwent subsequent hysterectomy. The main complications associated with conization were hemorrhage and cervical stenosis. Bleeding occurred in 5 (5.4%) of the patients, and cervical stenosis occurred in 2 (2.2%).Conclusion:Cervical intraepithelial neoplasia is diagnosed more accurately using conization than by colposcopic multiple punch biopsies. Conization can also play an important role in the treatment for CIN ......
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