盐酸乙酰谷酰胺\甘露醇联合应用治疗颈性眩晕38例临床观察
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[摘要] 目的:观察乙酰谷酰胺、甘露醇联合应用治疗颈性眩晕的临床疗效。方法:采用随机、平行对照试验,将78例颈性眩晕患者分成两组,对照组40例,复方丹参片2片每天3次口服,盐酸氟桂利嗪胶囊 5~10 mg,每晚1次口服,静脉滴注肌苷注射液。试验组38例,在对照组基础上,加用乙酰谷酰胺、甘露醇静脉滴注治疗,两组疗程均为1 周。比较两组临床疗效。结果:治疗1周后,试验组(n=38)的总有效率为94.73%,显效率为42.10%,而对照组(n=42)的总有效率为85.00%,显效率为27.50%,两组间治疗总有效率、显效率比较,均差异有统计学意义(P<0.05)。结论:乙酰谷酰胺、甘露醇联合应用治疗颈性眩晕疗效确切,安全可靠。
[关键词] 乙酰谷酰胺;甘露醇;颈性眩晕;临床观察
[中图分类号] R971 [文献标识码]A[文章编号]1674-4721(2011)07(b)-021-02
Clinical observation of hydrochloric acid acetyl glutamine, mannitol treatment of cervical vertigo combination of 38 cases
FENG Songqing, WU Jinxuan
Internal Medicine Department of People′s Hospital in Duanzhou District, Zhaoqing City, Guangdong Province, Zhaoqing 526040, China
[Abstract] Objective: To observe acetyl glutamine, mannitol treatment of combined the efficacy of cervical vertigo. Methods: A randomized, parallel controlled trial, 78 cases of cervical vertigo patients were divided into 2 groups, control group, 40 cases of compound Danshen tablets 2 tablets 3 times a day orally. Flunarizine hydrochloride capsules 5-10 mg, night one time oral, intravenous infusion of inosine injection. Experimental group of 38 patients in the control group based on the addition of acetyl-glutamine, mannitol infusion therapy, treatment lasted for 1 week. Comparison of two clinical efficacy. Results: 1 week after treatment, the experimental group (n=38) of the total effective rate of 94.73%, markedly effective rate of 42.10%, while the control group (n=42) of the total effective rate of 85.00%, markedly effective rate of 27.50%, total treatment between the two groups efficient, effective rate was significant difference (P<0.05). Conclusion: Acetyl-glutamine, mannitol treatment of cervical vertigo in combination is safely and reliablly.
[Key words] Acetyl glutamine; Mannitol; Cervical vertigo; Clinical observation
颈性眩晕是指颈椎及有关软组织(关节囊、韧带、神经、血管、肌肉等)发生器质性或功能性变化所引起的眩晕,亦称Barre-Lieon综合征。临床治疗手段多样,疗效不一,有以颈石膏固定,颈牵引等物理治疗。有针对内耳血供障碍,改善内耳微循环使用地巴唑、烟酸、培他司汀、氟桂利嗪、复方川芎嗪、复方丹参片、甲磺酸阿米三嗪萝巴新片等药物,有使用前庭镇静剂,如地西泮、异丙嗪、苯海拉明等。现笔者观察了乙酰谷酰胺、甘露醇联合应用治疗颈性眩晕的临床疗效,报道如下:
1 资料与方法
1.1 一般资料
1.1.1 入选标准选取2008年1月~2010年12月 ......
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