盐酸氟西汀与美利曲辛治疗产后广泛性焦虑症对照研究(1)
 |
| 第1页 |
参见附件(1969KB，2页)。
[摘要] 目的：探讨盐酸氟西汀与美利曲辛治疗产后广泛性焦虑症对比情况，对相关治疗提供药物参考。方法：将产后广泛性焦虑症患者80例随机平分为治疗组与对照组各40例，对照组常规给予盐酸美利曲辛治疗，治疗组给予盐酸氟西汀治疗。结果：治疗后治疗组HAMD量表评分与对照组比较差异有统计学意义(P<0.05)，说明治疗组治疗后HAMD量表评分下降优于对照组。治疗组的总有效率为95.0%，对照组总有效率为75.0%，治疗组的临床疗效明显好于对照组(P<0.05)，差异有统计学意义。治疗组未出现不良反应，对照组出现失眠1例，口干1例，未作特殊治疗，症状自行缓解；两组不良反应发生率差异无统计学意义(P>0.05)。结论：相对于美利曲辛来说，盐酸氟西汀治疗产后广泛性焦虑症能有效降低HAMD量表评分，提高治疗有效率，且无明显不良反应，值得推广应用。
[关键词] 产后；广泛性焦虑症；盐酸氟西汀；美利曲辛；HAMD量表评分
[中图分类号] R971 [文献标识码]B[文章编号]1674-4721(2011)08(b)-083-02
Control study of fluoxetine and melitracen in treatment of postpartum generalized anxiety disorder
FU Xuefang, LUO Qin, ZOU Lianying, HE Suqiong
Obstetrics and Gynecology Department of Dongcheng Hospital in Dongguan City, Guangdong Province, Dongguan 523700, China
[Abstract] Objective: To investigate the fluoxetine and melitracen treatment of postpartum comparison of generalized anxiety disorder, drugs for treatment of related references. Methods: 80 patients with postpartum generalized anxiety disorder were randomly divided into the treatment group and control group of 40 patients. The control group were given conventional treatment melitracen hydrochloride, the treatment group were received fluoxetine treatment. Results: After treatment, HAMD scale score compared with the control group was statistically significant (P<0.05), the treatment group HAMD scale scores decreased more than the control group. Treatment group, the total effective rate was 95.0%, the total effective rate was 75.0% in the control group, the clinical efficacy of the treatment group was significantly better than the control group (P<0.05), the difference was statistically significant. Treatment group had no adverse reactions, control group had insomnia 1 case, dry mouth 1 case, who had no special treatment, the symptoms relieved by itself; there was no significant difference of the incidence of adverse reactions between two groups (P>0.05). Conclusion: Comparing with melitracen, the fluoxetine treatment of generalized anxiety disorder after childbirth can reduce the HAMD scale score, improve the treatment efficiency, without significant adverse reactions, it should be widely applied ......
您现在查看是摘要介绍页，详见PDF附件(1969KB，2页)。