p53基因第72位密码子基因多态性(2)
综上所述,p53 codon72Arg/Arg基因型是湖北地区汉族女性发生HPV16相关宫颈癌的重要遗传易感因素,对于制定基因水平的宫颈癌筛查策略有重要意义。[参考文献]
[1]Storey A,Thomas M,Kalita A,et al. Role of a p53 polymorphism in the development of humanpapillomavirus-associated cancer[J]. Nature,1998,393:229-234.
[2]Koushik A,Plat RW,Franco EL. p53 codon 72 polymorphism and cervicalneoplasia:a meta-analysis review[J]. Cancer Epidemiol ......
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