早发型重度子痫前期62例临床分析(1)
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[摘要] 目的 探讨早发型重度子痫前期的处理方法及对围生期母婴预后的影响。 方法 回顾性分析2005年1月～2010年11月本院产科62例早发型重度子痫前期患者的临床资料，根据发病孕周分为A组(<28周)11例、B组(28～31+6周)30例，C组(32～33+6周)21例。 结果 3组孕产妇并发症发生率比较差异无统计学意义(P > 0.05)；新生儿窒息率及围生儿死亡率随孕龄减小而升高(P < 0.05)，B组期待治疗时间明显长于A、C组(P < 0.05)，A、C组间比较差异无统计学意义(P > 0.05)。 结论 对早发型重度子痫前期患者应严密监护母胎情况，并适时终止妊娠。
[关键词] 早发型重度子痫前期；并发症；母婴结局；临床分析
[中图分类号] R714.24+5 [文献标识码] A [文章编号] 1674-4721(2012)04(a)-0055-02
Clinical analysis of 62 cases with early onset severe pre-eclampsia
HUANG Tao
Dipartment of Obstetrics and Gynecology, Beiliu People′s Hospital of Guangxi Zhuang Autonomous Region, Beiliu 537400, China
[Abstract] Objective To inverstigate the clinical treatment and the impact on the prognosis of perinatal mathers and infants of early onset severe pre-eclampsia. Methods Retrospective study was carried out on 62 patients with early onset severe pre-eclampsia from January 2005 to November 2010. They were divided into three groups according to gestational weeks: group A (<28 weeks), group B (28～31+6 weeks) and group C (32～33+6 weeks). Results The incidence of complication was no significant difference among the three groups (P > 0.05); The rates of neonatal asphyxia and perinatal mortality complications among these three groups was decrease with the increase of gestational (P < 0.05). The duration time of expectant treatment in group B was significantly longer than those in the other two groups (P < 0.05), but there was no significant difference among group A and group C (P > 0.05). Conclusion It is necessary to monitor the conditions of the methers and fetuses close and adopt appropriate methods to teminate pregnancy.
[Key words] Early onset severe pre-eclampsia; Complication; Matemal and child outcome; Clinical analysis
子痫前期为妊娠期高血压疾病(妊高征)之一，也是孕产妇及围生儿死亡的重要原因，尤其是未足月的早发型重度子痫前期，因发病时间早、离足月妊娠较远、程度较重，是妇产科医师面临的难题，处理起来非常棘手，因此在临床上越来越受到重视。目前对早发型重度子痫前期发病时间的界定仍有争议，有学者将32孕周为界限将重度子痫前期分为早发型和晚发型[1]，但国内更多学者倾向于将34孕周前发病的重度子痫前期定义为早发型。本文对在本院住院分娩的孕周在34周以前的62例早发型重度子痫前期患者临床资料进行回顾性分析，主要探讨该病处理方法及不同孕周的临床妊娠结局，现报道如下：
1 资料与方法
1.1 一般资料
所选研究对象2005年1月～2010年11月本院产科的62例重度子痫前期患者，发病时孕龄均不足34周，并符合《妇产科学》[2]第7版重度子痫前期诊断标准 ......
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