[摘要] 目的 比较不同术式对肺癌患者的凝血及炎性因子的影响。 方法 选取2009年9月～2011年11月于本院进行手术治疗的78例肺癌患者为研究对象，将其根据术式分为对照组(开胸手术组)39例和观察组(胸腔镜手术组)39例，对两组患者术前及术后3、7 d的APTT、TT、PT及血清IL-10、CRP、IL-8水平进行比较。 结果 观察组术后3、7 d的APTT、TT、PT及血清IL-10、CRP、IL-8水平均低于对照组，且均呈现先升后降的变化规律，术后比较，均P < 0.05，差异有统计学意义。 结论 腹腔镜手术对肺癌患者的凝血及炎性状态影响均较小。

    [关键词] 开胸手术；腹腔镜手术；肺癌；凝血；炎性状态

    [中图分类号] R734.2 [文献标识码] A [文章编号] 1674-4721(2012)06(a)-0042-02

    Influence of different operations for coagulation and inflammatory factors of patients with lung cancer

    SUN Fubing

    Department of Cardiothoracic Surgey, the People′s Hospital of Neixiang County in Henan Province, Neixiang 474354, China

    [Abstract] Objective To compare the influence of different operations for coagulation and inflammatory factors of patients with lung cancer. Methods Seventy-eight patients with lung cancer were selected as research object in our hospital from September 2009 to November 2011, and they were randomly divided into control group (thoracotomy group) 39 cases and observation group (laparoscopic surgery group) 39 cases ......