[摘要] 肿瘤坏死因子-α是通过结合跨膜受体发挥多种生理作用的多效应细胞因子，本文着重介绍其调节炎性反应、细胞凋亡和促进改善脑缺血方面研究的最新进展。

    [关键词] 肿瘤坏死因子-α(TNF-α)；炎性反应；细胞凋亡；脑缺血

    [中图分类号] R36 [文献标识码] A [文章编号] 1674-4721(2012)07(a)-0018-03

    Pharmacological and Physiological research of TNF-α

    QIU Yanlong1 LI Shuhua2 MU Xiangshan3 ZHANG Jiguo1 CAO Yongcang3

    1.Taishan Medical University Pharmaceutical College, Shandong Province, Tai'an 271000, China; 2.Pharmacy Department, the Fourth People's Hospital of Tai'an City in Shandong Province, Tai'an 271000, China; 3.Pharmacy Department, Chinese Medicine Hospital of Tai'an City in Shandong Province, Tai'an 271000, China ......