妊娠期生殖道支原体感染的耐药监测(1)
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[摘要] 目的 分析2011年佛山地区妊娠期妇女生殖道支原体感染情况及抗菌药物耐药情况,重点分析阿奇霉素对妊娠期生殖道支原体的耐药情况。 方法 以2011年1~12月本院门诊及住院收治的孕妇为监测对象,统计妊娠期生殖道支原体感染的发生情况,支原体属检测采用支原体分离培养药敏试剂盒,测试12种抗菌药物的敏感性。 结果 妊娠期生殖道支原体感染阳性率为33.76%,其中解脲支原体感染阳性率为33.28%,人型支原体感染阳性率为4.20%,解脲支原体+人型支原体混合感染阳性率为3.72%。12种抗菌药物的耐药率依次为:环丙沙星(58.61%)>红霉素(24.64%)>司巴沙星(19.14%)>罗红霉素(12.44%)>阿奇霉素(11.48%)=克拉霉素(11.48%)>左旋氧氟沙星(11.24%)>氧氟沙星(11.00%)>四环素(6.70%)>强力霉素(3.59%)>美满霉素(2.87%)>交沙霉素(0.48%)。 结论 妊娠期生殖道支原体感染以解脲支原体感染为主,阿奇霉素对生殖道支原体感染仍保持较高的敏感性,可为作治疗妊娠期生殖道支原体感染的首选药物。
[关键词] 生殖道支原体;妊娠期;阿奇霉素;耐药监测
[中图分类号] R714.251 [文献标识码] C [文章编号] 1674-4721(2012)07(a)-0193-03
The resistance monitoring in mycoplasma genitalium infection during gestation period
WU Chuliang1 DENG Shaochang1 GAO Jianbin1 LAI Yu2
1.The Affiliated Nanhai Maternity and Child Care Hospital of Guangzhou University of Chinese Medicine in Guangdong Province, Foshan 528200, China; 2.Guangdong Pharmaceutical University in Guangdong Province, Guangzhou 510006, China
[Abstract] Objective To analyze the situation of mycoplasma genitalium infection during gestation period and the antimicrobial drug resistance in Foshan District in 2011, and focus on the analysis of Azithromycin on the antimicrobial drug resistance situation of mycoplasma genitalium during gestation period. Methods The pregnant women enrolled in our hospital from January to December in 2011 were chosen as the monitoring objects, and the occurrence situation of mycoplasma genitalium infection during gestation period were calculated ......
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