胺碘酮干预治疗恶性室性心律失常及心源性猝死疗效分析(1)
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[摘要] 目的 观察胺碘酮治疗恶性室性心律失常以及心源性猝死的疗效。 方法 将165例ICU伴发恶性室性心律失常住院患者采用随机数字表法分为治疗组和对照组。对照组进行针对原发病及症状体征的综合治疗。治疗组在此基础上加用胺碘酮300 mg/d口服，连服1周后改为100 mg/d，口服，然后将两组患者恶性室性心律失常复发率及心性源猝死发生率进行比较。 结果 治疗组恶性室性心律失常复发率及心性源猝死发生率分别为18.60%和6.98%，均显低于对照组，P < 0.05，差异有统计学意义。 结论 胺碘酮可有效控制恶性室性心律失常以及心源性猝死，临床价值较高。
[关键词] 胺碘酮；恶性心律失常；心源性猝死；ICU
[中图分类号] R972+.2 [文献标识码] A [文章编号] 1674-4721(2012)07(b)-0088-03
Analysis on the effect of amiodarone in the treatment of malignant ventricular arrhythmia and cardiogenic sudden death
CHEN Taizhong
Emergency Department, the TCM Hospital of Huaining County in Anhui Province, Huaining 246121, China
[Abstract] Objective To observe the effect of amiodarone in the treatment of malignant ventricular arrhythmia and cardiogenic sudden death. Methods One hundred and sixty-five patients with malignant ventricular arrhythmias in department of ICU were divided into treatment group and control group according to random number table. The control group were treated with comprehensive treatment based on the primary disease, symptoms and signs, and the treatment group were treated with oral amiodarone 300 mg/d based on the treatment of control group, then they were continuous treated one week, then the dose of amiodarone was decreased to 100 mg/d, then the rates of malignant ventricular arrhythmia recurrence and cardiogenic sudden death of two groups were compared. Results The rates of malignant ventricular arrhythmia recurrence and cardiogenic sudden death of treatment group were 18.60% and 6.98%, they were both lower than those of control group, P < 0.05, there were both significant differences. Conclusion The amiodarone can effectively control the rates of malignant ventricular arrhythmia and cardiogenic sudden death, and its clinical value is higher ......
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